Assuntos
Doença das Coronárias , Hipertensão , Infarto do Miocárdio , Anti-Hipertensivos , Humanos , LipídeosAssuntos
Doenças Cardiovasculares/prevenção & controle , LDL-Colesterol/sangue , Complicações do Diabetes/prevenção & controle , Diabetes Mellitus/sangue , Inibidores de Hidroximetilglutaril-CoA Redutases/uso terapêutico , Doenças Cardiovasculares/etiologia , Humanos , Inibidores de Hidroximetilglutaril-CoA Redutases/administração & dosagemAssuntos
Doença da Artéria Coronariana/prevenção & controle , Dislipidemias/tratamento farmacológico , Hiperglicemia/complicações , Hipolipemiantes/uso terapêutico , Doença da Artéria Coronariana/etiologia , Doença da Artéria Coronariana/fisiopatologia , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/fisiopatologia , Dislipidemias/complicações , Dislipidemias/fisiopatologia , Humanos , Hiperglicemia/fisiopatologia , Resistência à Insulina , Fatores de RiscoAssuntos
Anticolesterolemiantes/uso terapêutico , Colesterol/sangue , Doença das Coronárias/prevenção & controle , Hipercolesterolemia/tratamento farmacológico , Educação de Pacientes como Assunto , Guias de Prática Clínica como Assunto , Doença das Coronárias/sangue , Doença das Coronárias/etiologia , Humanos , Hipercolesterolemia/sangue , Hipercolesterolemia/complicações , Fatores de Risco , Estados UnidosRESUMO
IT IS POSSIBLE TO PREDICT THE POPULATION AT RISK FOR ATHEROTHROMBOTIC DISEASE (ATD) WITH HIGH ACCURACY USING ONLY THREE RISK FACTORS: dyslipidemia, cigarette smoking and hypertension. Using a global risk factor graph with the cholesterol retention fraction (CRF, or [low-density lipoprotein cholesterol - high-density lipoprotein cholesterol]/low-density lipoprotein cholesterol) on the vertical axis and systolic blood pressure (SBP) on the horizontal axis, a threshold line can be drawn using CRF-SBP plots (0.74, 100) and (0.49, 140). Eighty-five per cent of all ATD patients in the Bowling Green Study database were observed to lie above this threshold line. Of the 15% of ATD patients with CRF-SBP plots below the threshold line, most were cigarette smokers, leaving only 6% of patients with ATD in the Bowling Green Study database whose risk for ATD could not be predicted by CRF-SBP plot position above the threshold line and/or cigarette smoking status.
RESUMO
BACKGROUND: Greyhounds frequently have laboratory values that are outside reference intervals established for dogs. Our recognition of increased serum creatinine concentrations in several Greyhounds posed a problem when evaluating a Greyhound with suspected renal disease. OBJECTIVE: The purpose of this study was to compare serum creatinine concentrations between Greyhound and non-Greyhound dogs. METHODS: Thirty retired racing Greyhounds and 30 age- and gender-matched control non-Greyhound dogs were evaluated. Serum creatinine concentrations in both groups were measured using a standard biochemical method and compared statistically using a Kruskal-Wallis test. RESULTS: Creatinine concentration was significantly higher in the Greyhounds (P <.01) than in the control group. CONCLUSION: Greyhounds have a higher serum creatinine concentration than do non-Greyhound dogs. This idiosyncrasy should be taken into account when evaluating healthy Greyhounds and those with suspected renal disease.
