1.
Bioorg Med Chem Lett
; 14(16): 4157-60, 2004 Aug 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15261261
RESUMO
The preparation of alpha-methylbenzyl thioureas and their biological activity against varicella zoster virus is described. Several analogs demonstrated IC50s<0.1 microM and their SAR are discussed. These compounds represent a novel class of potent and selective nonnucleoside inhibitors of varicella zoster virus.
