RESUMO
In our study, 7 bioptical specimens of intestinal T-cell lymphoma are described. This tumour occurs in the small intestine of adults who may have a history of malabsorption. The patients present clinically with intestinal perforation, enterorrhagia, or ileus. The gross appearance varies: the tumour may take the form of multiple ulcers or of a huge exulcerated lesion. The cytomorphological features are variable. Bizarre multinucleated cells may be sometimes present. The reactive cellular background is usually dominated by histiocytes or eosinophilic granulocytes. Immunohistochemically, the tumour cells stain in reactions with antibodies to pan T-cell markers, occasionally to CD8 and CD30. The positivity of tumour cells for markers of intraepithelial T-cells and for cytotoxic molecules has been demonstrated previously.
Assuntos
Neoplasias Intestinais/patologia , Intestino Delgado , Linfoma de Células T/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Humanos , Neoplasias Intestinais/diagnóstico , Linfoma de Células T/diagnóstico , Masculino , Pessoa de Meia-IdadeRESUMO
In series of 248 gastric carcinomas from surgical resections the occurence of argyrophil and argentaffin cells was studied. These cells were distinctly more frequent in diffuse than in tubular carcinomas. In all cases with both types of APUD-cells, argyrophil cells were more numerous than argentaffin cells. These tumors are considered to be a variant of current gastric carcinoma, with more pronounced APUD-differentiation of neoplastic cells. This variant stands apart from carcinoid tumors and also from those rare nasal adenocarcinomas with argentaffin cells.
