Diseño y aplicación de un Plan de Cuidados para un paciente pediátrico en el Role2E de Herat (Afganistán) durante los meses de abril y mayo de 2015 / Design and Application of a Care Plan for a paediatric patient in the Role2E of Herat (Afghanistan) in the months of April and May of 2015

El trabajo de enfermería se basa en un método científico, el Proceso de Atención de Enfermería (PAE), que puede aplicarse en cualquier situación y medio. En este artículo, describimos la elaboración e implementación de un Plan de Cuidados de Enfermería para una niña afgana de aproximadamente 2 años, que fue remitida al hospital español desplegado en Herat, Afganistán (Role 2E), en Abril de 2015, para valoración y tratamiento por quemaduras en brazo derecho y región anterior del tórax, tras haberle caído agua hirviendo. Se practicaron curas con sedación (por su corta edad) cada 48 horas. Siguiendo el PAE, se estandarizaron los cuidados a aplicar y se fijaron unas líneas de acción encaminadas a la continuidad de los mismos tras el relevo del personal sanitario español, así como la prevención de futuros problemas derivados de las secuelas de las lesiones

The nurse work is based on a scientific method; the Nursing Process (Proceso de Atención de Enfermería -PAE- in Spanish) which can be applied in every situation and milieu. In this article, we describe the design and implementation of a Nursing Care Plan for a two-year-old Afghan girl who had been sent to the Spanish hospital deployed in Herat, Afghanistan (Role 2E) in April 2015 to be checked and treated of burns on her right arm and anterior chest after hot water had fallen upon her. Due to her short age, dressings with sedation were performed every 48 hours. Acording to the NP, both the care to be applied was established together with the course of action to be followed after the replacement of the Spanish staff in order to prevent future problems directly derived from the consequences of the injuries

IL-15 super-agonist (ALT-803) enhances natural killer (NK) cell function against ovarian cancer.

OBJECTIVE: Natural killer (NK) cells represent a powerful immunotherapeutic target as they lyse tumors directly, do not require differentiation, and can elicit potent inflammatory responses. The objective of these studies was to use an IL-15 super-agonist complex, ALT-803 (Altor BioScience Corporation), to enhance the function of both normal and ovarian cancer patient derived NK cells by increasing cytotoxicity and cytokine production. METHODS: NK cell function from normal donor peripheral blood mononuclear cells (PBMCs) and ovarian cancer patient ascites was assessed using flow cytometry and chromium release assays ±ALT-803 stimulation. To evaluate the ability of ALT-803 to enhance NK cell function in vivo against ovarian cancer, we used a MA148-luc ovarian cancer NOD scid gamma (NSG) xenogeneic mouse model with transferred human NK cells. RESULTS: ALT-803 potently enhanced functionality of NK cells against all ovarian cancer cell lines with significant increases seen in CD107a, IFNγ and TNFα expression depending on target cell line. Function was also rescued in NK cells derived from ovarian cancer patient ascites. Finally, only animals treated with intraperitoneal ALT-803 displayed an NK dependent significant decrease in tumor. CONCLUSIONS: ALT-803 enhances NK cell cytotoxicity against ovarian cancer in vitro and in vivo and is able to rescue functionality of NK cells derived from ovarian cancer patient ascites. These findings suggest that ALT-803 has the potential to enhance NK cell-based immunotherapeutic approaches for the treatment of ovarian cancer.

A new robotic endoscope manipulator. A preliminary trial to evaluate the performance of a voice-operated industrial robot and a human assistant in several simulated and real endoscopic operations.

We report our learning experience in simulated and real surgical tasks with a new voice-controlled robotic endoscope manipulator: an industrial robot with the tool-holder arm modified to support the optic and camera. The manipulator control-card programs have been rewritten to meet the needs of endoscopic surgeons. For this preliminary work, systems engineers with an additional monitor monitored, recorded, and compared the percentage effectiveness and precision of the responses of the robotic and human assistant to successive oral commands during the several different experimental surgical tasks. Simultaneously, to help develop this voice-commanded system for future, more precise robotic manipulation of surgical instruments, they measured the cartesian and spherical coordinates of successive positions of the optic. In unexpectedly difficult experimental conditions, the tireless robot proved more precise and effective than the demonstrably fatigable human: the steadier screen images of the robotic manipulations helped the surgeon tie knots in 7-0 sutures.

Preperitoneal hernioplasty performed with needlescopic instruments (microlaparoscopy).

We treated a series of 30 patients who had a Nyhus type II, III, or IV inguinal hernia without associated pathology by laparoscopic surgery using 2-mm surgical instruments and a modified preperitoneal Dulucq technique. A 30 degrees optic was used, and the repair was reinforced by an accordion-folded, polypropylene mesh introduced through a 10-mm optic needleport. There were no postoperative complications, and all patients were discharged 24 hours after operation. At 6 months there has been no recurrence of hernia. It was evident that the 2-mm procedure produced less surgical trauma.