1.
Nat Prod Commun
; 4(3): 395-8, 2009 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19413120
RESUMO
Three wild strains of C. acutatum have been investigated for their phytotoxic secondary metabolites involved in anthracnose disease. In addition to known compounds, a new macrolide 6 has been isolated and characterized by spectroscopic analysis.
Assuntos
Colletotrichum/química , Macrolídeos/análise , Macrolídeos/isolamento & purificação , Espectroscopia de Ressonância Magnética , Estrutura Molecular
2.
Bioorg Med Chem Lett
; 16(22): 5836-9, 2006 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16950623
RESUMO
A novel metabolite (-)-1 was isolated as its peracetylated derivative, (-)-2-(3',4'-diacetoxyphenyl)-3,4-diacetoxytetrahydrofuran (2), from a strain of the phytopathogenic fungus Colletotrichum gloeosporioides CECT 20122. The synthesis of (-)-1 was carried out by ring-closing metathesis of diene 6 and stereoselective dihydroxylation of a dihydrofuran derivative 7 as key steps. The tetraol (-)-1 showed free radical scavenging activity comparable to that of BHT, caffeic acid or protocatechuic acid.
