Efficacy and safety of endovascular coiling vs surgical clipping for patients with ruptured carotid-ophthalmic aneurysm: A protocol for systematic review and meta-analysis.

BACKGROUND: Carotid-ophthalmic aneurysms are relatively rare, and represent 1% of all intracranial aneurysms. Generally, endovascular coiling and surgical clipping are the 2 most commonly used methods to treat ruptured carotid-ophthalmic aneurysms, it provides the most favorable outcome for a patient. This study aims to assess the efficiency and safety of endovascular coiling vs surgical clipping for patients with a ruptured carotid-ophthalmic aneurysm. METHODS: A comprehensive systematic literature review was done in PubMed, EMBASE, Cochrane Library, Web of Science, Scopus, China National Knowledge Infrastructure (CNKI), and WanFang databases. Only randomized trials that compared endovascular coiling with surgical clipping in patients with ruptured carotid-ophthalmic aneurysm was included. Data was extracted independently by 2 review authors. Moreover, the quality of study and bias risk was evaluated by utilizing an appropriate method. Triallists will be contacted to acquire missing information. The data is presented as risk ratio and mean difference, or standardized mean difference with 95% confidence intervals. RESULTS: The results from the present research shall be published in a peer-reviewed journal. CONCLUSION: The present study summarizes the direct and in-direct evidence to judge the efficiency and safety of these 2 methodologies to treat ruptured carotid-ophthalmic aneurysms and attempt to find the most efficiency and safety therapeutical method. ETHICS AND DISSEMINATION: The present study is a meta-analysis based on published evidence. As a result, ethics approval and patient consent are not needed.

Route-dependent switch between hierarchical and egalitarian strategies in pigeon flocks.

The mechanisms that underlie fascinating inter-individual interactions among animal groups have attracted increasing attention from biologists, physicists, and system scientists. There are two well-known types of interaction patterns: hierarchical and egalitarian. In the former type, individuals follow their leaders, whereas they follow their neighbors in the latter. Using high-resolution spatiotemporal data derived from the free flights of a flock of pigeons, we show that pigeon flocks actually adopt a mode that switches between the two aforementioned strategies. To determine its flight direction, each pigeon tends to follow the average of its neighbors while moving along a smooth trajectory, whereas it switches to follow its leaders when sudden turns or zigzags occur. By contrast, when deciding how fast to fly, each pigeon synthesizes the average velocity of its neighbors. This switching mechanism is promising for possible industrial applications in multi-robot system coordination, unmanned vehicle formation control, and other areas.

A guideline-based decision support system for headache diagnosis.

The ratio of correct diagnosis for primary headache has always been relatively low for general practitioners due to the unacquaintance with headache guideline in Chinese primary hospitals. This study proposed a computerized headache guideline method using SAGE module and developed a decision support system for headache diagnosis, which could be expected to help general practitioners of primary hospitals improve diagnostic accuracy. 282 previously diagnosed cases from EMR were used to evaluate the diagnostic accuracy of the system, the result is: migraine 144/153 (94.1%), tension-type headache 89/100 (89.0%), cluster headache 10/11 (90.9%) and chronic daily headache 53/57(93.0%). The proposed system is in the starting phase of the implementation at the outpatient department of Neurology in Chinese PLA general hospital.

Trail characteristics as correlates of urban trail use.

PURPOSE: The purpose of this study was to identify the environmental correlates of urban trail use. DESIGN: Three multiuse urban trails at least 15 miles in length were selected. Trails were divided into one-half-mile segments (N = 102 total segments) and marked in the field. An audit of each trail was completed identifying built environmental features. A cross-sectional count of trail users was completed at each segment estimating the type of use, age, gender. SETTING: Data collection occurred on urban trails in Chicago, Dallas, and Los Angeles. SUBJECTS: Trained observers counted 17,338 users across the three trails. MEASURES: The SPACES for Trails instrument was used, and a trail count data collection sheet was developed. ANALYSIS: Univariate and multivariate Poisson regressions controlling for location of trail and density of the population within 1 mile of the trail. RESULTS: Positive associations with trail use were observed for mixed views (beta = .33, p < .0001), streetlights (beta = .30, p < .0001), good trail condition (beta = .28, p < .0001), and the presence of cafés (beta = .38, p < .0001) and other trailside facilities (beta =.08, p < .0001). Negative associations were observed for litter (beta = -.22, p < .0001), noise (beta = -.41, p < .0001), higher vegetation density (beta = -. 10, p < .001), drainage features (beta = -.67, p < .0003), natural areas adjacent to the trail (beta = -.39, p < .0001), and tunnel present (beta = -.20, p < .04). CONCLUSIONS: These correlates should be confirmed in other studies and if supported should be considered in the promotion and design of urban trails.