1.
Chem Commun (Camb)
; 57(26): 3279-3282, 2021 Apr 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33651061
RESUMO
A copper-catalyzed borylaminomethylation of multiple carbon-carbon bonds with N,O-acetal and bis(pinacolato)diboron has been disclosed that offers efficient and expedient access to γ-amino boronates. The products contain a valuable amine and boronate, which are amenable to further elaboration, and have versatile synthetic utilities.
2.
Chem Commun (Camb)
; 56(54): 7483-7486, 2020 Jul 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32497160
RESUMO
A copper-catalyzed borylative amidation of vinyl arenes with isocyanates and bis(pinacolato)diboron has been developed. This new protocol, which can be performed on a gram-scale, utilizes isocyanates as simple precursors to provide access to a range of boryl alkyl amides. The products contain valuable amide and boronate, which are amenable for further elaboration, and have versatile synthetic utilities.