Role of TNF-αin retinal neural degeneration diseases / 基础医学与临床

Retinal neural degeneration diseases is one of the main causes of vision loss , TNF-αas an inflammatory cytokine with pleiotropic biological activity , after binding to its receptor by a variety of signaling pathways , may have play critical role in pathogenesis of retinal neural degeneration diseases including glaucoma , ischemic retinop-athy, age-related macular degeneration and retinitis pigmentosa .