Reduced Echocardiographic Inotropy Index after Cardiopulmonary Bypass Is Associated With Complications After Cardiac Surgery: An Institutional Outcomes Study.

OBJECTIVE: Despite advances in echocardiography and hemodynamic monitoring, limited progress has been made to effectively quantify left ventricular function during cardiac surgery. Traditional measures, including left ventricular ejection fraction (LVEF) and cardiac index, remain dependent on loading conditions; more complex measures remain impractical in a dynamic surgical setting. However, the Smith-Madigan Inotropy Index (SMII) and potential-to-kinetic energy ratio (PKR) offer promise as measures calculable during cardiac surgery and potentially predictive of outcomes. Using echocardiographic and hemodynamic monitoring data, the authors aimed to calculate SMII and PKR values after cardiopulmonary bypass and understand associations with postoperative outcomes, adjusting for previously identified risk factors. DESIGN: Observational cohort study. SETTING: Tertiary care academic hospital. PATIENTS: The study comprised 189 elective adult cardiac surgical procedures from 2015-2016. INTERVENTION: None. MEASUREMENTS AND MAIN RESULTS: The primary outcome was postoperative mortality or organ system complication (stroke, prolonged ventilation, reintubation, cardiac arrest, acute kidney injury, new-onset atrial fibrillation). After adjustment, SMII <0.83 W/m2 independently predicted the primary outcome (adjusted odds ratio 2.19, 95% confidence interval 1.08-4.42); whereas PKR, LVEF, and cardiac index demonstrated no associations. When SMII and PKR were incorporated into a EuroSCORE II risk model, predictive performance improved (net reclassification index improvement 0.457; p = 0.001); whereas a model incorporating LVEF and cardiac index demonstrated no improvement (0.130; p = 0.318). CONCLUSION: The present study demonstrated that SMII, but not PKR, as a measure of cardiac function was associated with major complications. The study's data may guide investigations of more suitable perioperative goal-directed therapies to reduce complications after cardiac surgery.

Suture-button construct for interosseous ligament reconstruction in longitudinal radioulnar dissociations: a biomechanical study.

PURPOSE: Longitudinal radioulnar dissociation is a triad of injuries consisting of distal radioulnar joint disruption, interosseous ligament complex (IOLC) tear, and radial head fracture. This renders the forearm longitudinally unstable, resulting in proximal migration of the radius and ulnar-sided wrist degeneration. We hypothesized that reconstruction of the central band of the IOLC in cadaver forearms using a Mini-TightRope suture-button construct would restore native forearm stability. METHODS: We implanted 8 fresh-frozen cadaver arms with steel beads into the distal radius and ulna, mounted them on an MTS machine, and cyclically loaded them from 13 N distraction to 130 N compression. Bead motion was recorded fluoroscopically and analyzed using Image-Pro Express software. We measured distal ulnar forces using strain gauge transducers. Longitudinal radioulnar dissociation injuries were created by radial head excision and complete IOLC and triangular fibrocartilage complex disruption. At each stage, arms were tested with and without a radial head implant. We reconstructed the central band of the IOLC using a Mini-TightRope and tightened until the distal radioulnar joint was reduced fluoroscopically. We used multiple-comparison analysis of variance with Tukey's Honestly Significant Difference test for statistical analysis. RESULTS: The intact arms had an average radioulnar axial displacement of 0.7 ± 0.8 mm and distal ulnar impaction force of 16.7 ± 11.1 N (per 100 N of axial load on the forearm). After destabilization, the radioulnar displacement increased to 10.7 ± 3.9 mm (p < .001) and ulnar load increased 312%, to an average of 52.2 ± 25.7 N (p < .001). After IOLC reconstruction, average displacement decreased to 2.2 ± 0.9 mm with a distal ulnar load of 19.05 ± 13.5 N (not significantly different from intact arms). CONCLUSIONS: In this cadaveric study, Mini-TightRope IOLC reconstruction with or without a radial head prosthesis significantly reduced distal ulnar impaction forces to that of the native forearm, while limiting radioulnar displacement to near-anatomic levels.