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1.
Polymers (Basel) ; 16(10)2024 May 10.
Artigo em Inglês | MEDLINE | ID: mdl-38794553

RESUMO

This study details the synthesis and performance evaluation of a novel lightweight thermal and acoustic insulation material, resulting from the combination of a scleroglucan-based hydrogel and recycled rigid polyurethane waste powder. Through a sublimation-driven water-removal process, a porous three-dimensional network structure is formed, showcasing notable thermal and acoustic insulation properties. Experimental data are presented to highlight the material's performance, including comparisons with commercially available mineral wool and polymeric foams. This material versatility is demonstrated through tunable mechanical, thermal and acoustic characteristics, achieved by strategically adjusting the concentration of the biopolymer and additives. This adaptability positions the material as a promising candidate for different insulation applications. Addressing environmental concerns related to rigid polyurethane waste disposal, the study contributes to the circular economy.

2.
Math Biosci Eng ; 6(3): 493-508, 2009 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-19566122

RESUMO

Implantation of drug eluting stents following percutaneous transluminal angioplasty has revealed a well established technique for treating occlusions caused by the atherosclerotic plaque. However, due to the risk of vascular re-occlusion, other alternative therapeutic strategies of drug delivery are currently being investigated. Polymeric endoluminal pave stenting is an emerging technology for preventing blood erosion and for optimizing drug release. The classical and novel methodologies are compared through a mathematical model able to predict the evolution of the drug concentration in a cross-section of the wall. Though limited to an idealized configuration, the present model is shown to catch most of the relevant aspects of the drug dynamics in a delivery system. Results of numerical simulations shows that a bi-layer gel paved stenting guarantees a uniform drug elution and a prolonged perfusion of the tissues, and remains a promising and effective technique in drug delivery.


Assuntos
Angioplastia Coronária com Balão/métodos , Oclusão Coronária/terapia , Stents Farmacológicos/normas , Modelos Cardiovasculares , Angioplastia Coronária com Balão/instrumentação , Angioplastia Coronária com Balão/normas , Simulação por Computador , Análise de Elementos Finitos , Humanos
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