Pseudoaneurysm as an unusual complication in bone lengthening.

One of the risks of distraction osteogenesis-based techniques is the development of vascular complications, such as pseudoaneurysms associated with the osteotomies performed or the fixation elements of the external fixator used in the procedure. Pseudoaneurysm are formed when the tunica adventitia of the artery is injured, resulting in a gradual and persistent blood extravasation into the surrounding tissues that is encapsulated and connected to the arterial lumen. This report describes a rare case of a late-presentation pseudoaneurysm in the anterior tibial artery resulting from a tibial lengthening procedure aimed at addressing a leg length discrepancy in a 57-year-old female with severe peripheral neuropathy resulting from long-standing poorly controlled diabetes mellitus. We describe the diagnostic process, the treatment options and confirm how the shape of the bony callus can be a reliable indicator of this pathology, as has already been described in the literature.

Use of cryopreserved human amniotic membrane in the treatment of skin ulcers secondary to calciphylaxis.

Calciphylaxis is a rare condition characterized by skin ulceration and necrosis as a result of vascular calcification of the small and medium blood vessels of skin and subcutaneous tissues. It mainly occurs in patients with advanced chronic kidney disease and sometimes leads to complications with a fatal outcome. In this report, we describe the case of a 67-year-old male patient with end stage renal disease presenting painful skin ulcers on his lower limbs. The lesions had progressively grown and were associated to severe pain and decreased quality of life. The ulcers did not respond to conventional treatments and the patient underwent skin biopsy of these lesions obtaining anatomopathological findings compatible with calciphylaxis. In this report, we present an innovative treatment for skin ulcers secondary to calciphylaxis using cryopreserved amniotic membrane (AM) as a dressing in order to promote epithelialization of the wounds. After four applications, healing of the main ulcer and reduction in pain was achieved. In summary, applying cryopreserved AM probed to be a promising strategy to reduce pain and to enhance epithelialization and healing of chronic non-responsive ulcers in calciphylaxis.

Primer caso en la Región de Murcia (España) de linfoma anaplásico de células grandes asociado a implantes mamarios / First case in region of Murcia (Spain) of breast implant-associated anaplastic large cell lymphoma

El linfoma anaplásico de células gigantes asociado a implantes mamarios es una entidad extremadamente rara de la que, hasta enero de 2019, han sido diagnosticados 656 casos en 34 países con 17 muertes comunicadas. Se postula que su etiología es el resultado de una reacción a un cuerpo extraño como la prótesis y la inflamación crónica persistente que se deriva. Presentamos el primer caso de esta patología diagnosticado y tratado en la Región de Murcia, España. Se trata de una paciente con seroma crónico recidivante que aparece a los 5 años de la colocación de implantes mamarios tras diagnóstico y tratamiento por cáncer de mama. El diagnóstico definitivo se obtuvo en el estudio anatomopatológico e inmunohistoquímico de la cápsula periprotésica tras cirugía de retirada de implantes y capsulectomía completa bilateral. Se administró quimioterapia postoperatoria por recomendación del Comité de Tumores hospitalario

Breast implant-associated large cell anaplastic lymphoma is an extremely rare entity of which, until January 2019, 656 cases have been diagnosed in 34 countries with 17 reported deaths. It's etiology is postulated as the result of a foreign body reaction to the implant and the resultant chronic and persistent inflammation. We present the first case of this pathology diagnosed and treated in the Region of Murcia, Spain. A patient with chronic relapsing seroma that appears 5 years after breast implant placement after diagnosis and treatment for breast cancer. The definitive diagnosis was obtained in the pathological and immunohistochemical study of the periprosthetic capsule after implant removal surgery and bilateral complete capsulectomy. Postoperative chemotherapy was administered on the recommendation of the hospital Tumor Committee