[Paraneoplastic limbic encephalitis and lung cancer]. / Encefalitis límbica paraneoplásica y cáncer de pulmón.

Paraneoplastic limbic encephalitis (PLE) is a disorder characterized by severe cognitive dysfunction and seizures. It is usually associated with small cell lung carcinoma. Diagnosis is difficult because clinical markers are often lacking, and symptoms usually precede the diagnosis of cancer. Serological detection of antineuronal antibodies can be useful. We describe a patient with symptoms of limbic encephalitis, negative for paraneoplastic antibodies, in whom lung cancer was detected.

Encefalitis límbica paraneoplásica y cáncer de pulmón / Paraneoplastic limbic encephalitis and lung cancer

La encefalitis límbica paraneoplásica (ELP) es una entidad caracterizada por severos déficits cognitivos y crisis convulsivas. Suele asociarse a carcinoma de células pequeñas de pulmón. El diagnóstico de ELP es difícil, ya que los marcadores clínicos a menudo están ausentes, y los síntomas suelen preceder al diagnóstico del cáncer. La detección de anticuerpos antineuronales puede resultar útil. Presentamos un paciente con síntomas de encefalitis límbica, con anticuerpos paraneoplásicos negativos, en el que se detectó un cancer de pulmón (AU)

[Lemièrre's syndrome. Report of 2 new cases and review of the literature]. / Síndrome de Lemièrre. Descripción de dos nuevos casos y revisión de la literatura.

Septic thrombophlebitis of internal jugular vein following oropharyngeal infections, referred to as postanginal sepsis, was first described at the beginning of the century by Lemièrre. For diagnostic of Lemièrre's syndrome, distant metastatic abscesses from septic embolization are required. These are placed most frequently in the lungs, but also occurred in soft tissues. Two cases of this unusual syndrome seen in a year period, are reported in this brief communication. We described the first liver metastatic infection, in the syndrome. Successful result was observed when we use a low molecular weight heparin as treatment in the septic thrombophlebitis of internal jugular vein.

Mujer joven con múltiples lesiones ocupantes de espacio en el sistema nervioso central / Young woman with multiple space-occupying lesions in the central nervous system

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Síndrome de Lemièrre. Descripción de dos nuevos casos y revisión de la literatura / Lemièrre's syndrome. Description of two new cases and bibliographyc review

La tromboflebitis séptica de la vena yugular interna como complicación de las infecciones orofaríngeas, tras un cuadro de sepsis postangina, fue descrita por primera vez a principios de siglo por Lemièrre. Para el diagnóstico de este síndrome, se requiere la existencia de abscesos metastásicos a distancia. Estos se localizan más frecuentemente a nivel pulmonar, pero también se han descrito en tejidos blandos. En este trabajo presentamos dos nuevos casos de este infrecuente síndrome, observados en el período de un año. En nuestro conocimiento, no han sido descritos anteriormente abscesos metastásicos hepáticos en este cuadro, que observamos en uno de nuestros pacientes. También aportamos nuestra experiencia en el tratamiento con heparina de bajo peso molecular de la tromboflebitis venosa yugular, que forma parte de este síndrome (AU)

Septic thrombophlebitis of internal jugular vein following oropharyngeal infections, referred to as postanginal sepsis, was first described at the begining of the century by Lemièrre. For diagnostic of Lemièrre`s syndrome, distant metastatic abscesses from septic embolization are required. These are placed most frequently in the lungs, but also ocurred in soft tissues. Two cases of this inusual syndrome seen in a year period, are reported in this brief communication. We described the first liver metastatic infection, in the syndrome. Successful result was observed when we use a low molecular weight heparin as treatment in the septic thrombophlebitis of internal jugular vein (AU)

Varón de 62 años con lesiones cutáneas de larga evolución: un diagnóstico a primera vista / 62-year old male patient with long-term evolving cutaneous lesions: diagnosis at first glance

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Enema opaco

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Brucelosis aguda e infección por el virus de la inmunodeficiencia humana. Situación actual / Acute brucellosis and human inmunodeficiency virus infection update

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[Acute rhabdomyolytic alcoholic myopathy associated with acute alcoholic hepatitis]. / Miopatía aguda etílica rabdomiolítica asociada a hepatitis alcohólica aguda.

Acute rhabdomyolysis (ARM) is a clinico-biological syndrome characterized by the lesion of the skeletal muscle resulting in a disorder of the permeability at the membrane of the muscle cells, with the release of intracellular substances to the plasma, mainly proteins and ions. We present the case of a chronic alcoholic patient which, after a period of several days in which he increased his consumption of alcohol, developed clinical signs of acute rhabdomyolytic alcoholic myopathy (AREM) associated to acute alcoholic hepatitis (AAH). In the review of the literature, we did not find any description of the association between AREM and acute hepatitis of alcoholic origin. We consider the nonspecificity of the clinical signs of the AREM and we suggest the systematic assessment of creatine-phosphokinase in patients at risk.

[Infrequent clinical presentation of Askin's tumor]. / Tumor de Askin de presentación clínica infrecuente.

Malign small cell tumors in the thoracopulmonary region is a tumor of neuroectodermic origins with polymorphous and infrequent presentation. It is mostly found among young people, developing an aggressive and severe course. It is a small cell tumor involving small quantities of cytoplasm without glucogen, round or oval nucleus with disperse chromatin, and little prominent nucleolus without tendency of manifesting pseudo red spots, being PAS negative. Two cases which initially resembled pleuropulmonary infection are presented. Case 1: Sixteen year old male. Presented with a high fever, pleuritic thoracic pain, and a cough with little expectoration. He was diagnosed with severe pulmonary infection and parapneumonic right pleural discharge. His condition improved with antibiotic treatment, but the cough persisted. Thoracoabdominal echography showed right pleural discharge and possible hepatic mass. Surgical intervention was performed. Askin's tumor was detected by biopsy. He began treatment with chemotherapy. Case 2: Thirty-four year old woman. Presented with non-productive cough, pleuritic thoracic pain, and high fever. In the thoracic TAC, there was right pleural discharge along with images suggesting hypodense mass. Given the patient's lack of response to antibiotics, a thoracotomy was performed. The anatomopathological diagnosis was Atkin's tumor. After beginning treatment, the patient died after ten days.