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2.
PLoS One ; 16(6): e0252862, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34111187

RESUMO

The amount, size, complexity, and importance of Knowledge Graphs (KGs) have increased during the last decade. Many different communities have chosen to publish their datasets using Linked Data principles, which favors the integration of this information with many other sources published using the same principles and technologies. Such a scenario requires to develop techniques of Linked Data Summarization. The concept of a class is one of the core elements used to define the ontologies which sustain most of the existing KGs. Moreover, classes are an excellent tool to refer to an abstract idea which groups many individuals (or instances) in the context of a given KG, which is handy to use when producing summaries of its content. Rankings of class importance are a powerful summarization tool that can be used both to obtain a superficial view of the content of a given KG and to prioritize many different actions over the data (data quality checking, visualization, relevance for search engines…). In this paper, we analyze existing techniques to measure class importance and propose a novel approach called ClassRank. We compare the class usage in SPARQL logs of different KGs with the importance ranking produced by the approaches evaluated. Then, we discuss the strengths and weaknesses of the evaluated techniques. Our experimentation suggests that ClassRank outperforms state-of-the-art approaches measuring class importance.


Assuntos
Biologia Computacional/métodos , Bases de Dados Factuais , Humanos , Reconhecimento Automatizado de Padrão , Semântica
3.
BMC Biol ; 19(1): 12, 2021 01 22.
Artigo em Inglês | MEDLINE | ID: mdl-33482803

RESUMO

BACKGROUND: Pandemics, even more than other medical problems, require swift integration of knowledge. When caused by a new virus, understanding the underlying biology may help finding solutions. In a setting where there are a large number of loosely related projects and initiatives, we need common ground, also known as a "commons." Wikidata, a public knowledge graph aligned with Wikipedia, is such a commons and uses unique identifiers to link knowledge in other knowledge bases. However, Wikidata may not always have the right schema for the urgent questions. In this paper, we address this problem by showing how a data schema required for the integration can be modeled with entity schemas represented by Shape Expressions. RESULTS: As a telling example, we describe the process of aligning resources on the genomes and proteomes of the SARS-CoV-2 virus and related viruses as well as how Shape Expressions can be defined for Wikidata to model the knowledge, helping others studying the SARS-CoV-2 pandemic. How this model can be used to make data between various resources interoperable is demonstrated by integrating data from NCBI (National Center for Biotechnology Information) Taxonomy, NCBI Genes, UniProt, and WikiPathways. Based on that model, a set of automated applications or bots were written for regular updates of these sources in Wikidata and added to a platform for automatically running these updates. CONCLUSIONS: Although this workflow is developed and applied in the context of the COVID-19 pandemic, to demonstrate its broader applicability it was also applied to other human coronaviruses (MERS, SARS, human coronavirus NL63, human coronavirus 229E, human coronavirus HKU1, human coronavirus OC4).


Assuntos
COVID-19/patologia , Genômica/métodos , Bases de Conhecimento , Proteômica/métodos , SARS-CoV-2/fisiologia , COVID-19/metabolismo , COVID-19/virologia , Coronavirus/genética , Coronavirus/fisiologia , Infecções por Coronavirus/metabolismo , Infecções por Coronavirus/patologia , Infecções por Coronavirus/virologia , Genoma Viral , Humanos , Internet , Pandemias , SARS-CoV-2/genética , Proteínas Virais/genética , Proteínas Virais/metabolismo , Fluxo de Trabalho
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