Factores asociados a mortalidad en pacientes Covid-19 en un Hospital del norte de Perú / Factors associated with mortality in Covid-19 patients in a Hospital in northern Peru

Objetivo. Determinar los factores de riesgo sociodemográficos y clínicos relacionados con la mortalidad en pacientes COVID-19 en un Hospital del norte de Perú. Material y Métodos: la investigación se llevó a cabo en un Hospital del norte de Perú. La población la constituyeron 208 Historias Clínicas de pacientes COVID-19 atendidos entre Marzo a Julio del 2020. La variable independiente fueron los factores sociodemográficos tales como la edad, sexo y el estado civil y los factores clínicos como antecedentes epidemiológicos, los factores de riesgo (co-morbilidades) y el estado de salud y la variable dependiente fue la mortalidad Covid-19. Resultados: La mortalidad COVID-19 alcanzó al 46,20 % en pacientes mayores 65 años (51,90 %), de sexo masculino (60,40 %) y casados (65,40 %), con antecedentes epidemiológicos (37,5%), y factores de riesgo (comorbilidad) un 74,50 %, principalmente asociados con hipertensión arterial (8,2%), obesidad (3,4%) y diabetes mellitus II (1,9%), y comorbilidades indeterminadas (Otras) un 6,7%. No se presentó mortalidad en los pacientes cuyo estado de salud era Estable, mientras que los pacientes con estado de salud reservado y fallecieron representaron un 46,2%. Conclusión: La mortalidad por COVID-19 alcanzó un 46,20%; mayores de 65 años (51,90 %), de sexo masculino (60,40 %) y casados (65,40 %). Se encontró relación significativa entre factores sociodemográficos como la edad, factores clínicos (comorbilidad), en su mayoría hipertensión arterial, obesidad y diabetes mellitus II, y pacientes con estado de salud reservado con la mortalidad del COVID-19.

Objetive. To determine the sociodemographic and clinical risk factors related to mortality in COVID-19 patients in a Hospital in northern Peru. Material and Methods: the research was carried out in a Hospital in the north of Peru. The population was made up of 208 Clinical Histories of COVID-19 patients seen between March and July 2020. The independent variable was sociodemographic factors such as age, sex and marital status, and clinical factors such as epidemiological history, risk factors (co-morbidities) and health status and the dependent variable was Covid-19 mortality. Results: COVID-19 mortality reached 46.20% in patients older than 65 years (51.90%), male (60.40%) and married (65.40%), with an epidemiological history (37.5%) , and risk factors (comorbidity) 74.50%, mainly associated with arterial hypertension (8.2%), obesity (3.4%) and diabetes mellitus II (1.9%), and indeterminate comorbidities (Others) 6.7%. There was no mortality in patients whose health status was Stable, while patients with reserved health status and who died represented 46.2%. Conclusion: mortality from COVID-19 reached 46.20%; older than 65 years (51.90%),male(60.40%) and married (65.40%). A significant relationship was found between sociodemographic factors such as age, clinical factors (comorbidity), mostly arterial hypertension, obesity and diabetes mellitus II, and patients with a reserved health status with the mortality of COVID-19.

Hepatosplenic abscesses in an immunocompetent child with cat-scratch disease from Peru.

BACKGROUND: Cat-scratch disease (CSD) is a zoonotic infection caused by Bartonella henselae and B. clarridgeiae. The typical manifestations of CSD include regional lymphadenitis and fever. However, CSD can have a wide variety of clinical manifestations that can lead to incorrect diagnoses and prolonged hospital stays. CASE PRESENTATION: We present a case of a 3-year-old boy admitted to the pediatric service due to prolonged fever and abdominal pain. He received empirical antimicrobial treatment due to suspicion of infection. Abdominal ultrasound showed hepatosplenic abscesses. An IFA detected the presence of IgG antibodies against B. henselae (1:256). Patient was successfully treated with azithromycin and discharged after 7 weeks. CONCLUSIONS: Hepatosplenic abscesses in CSD are rarely reported, particularly in immunocompetent children, with this, only 36 cases in PubMed, Web of Sciences and Scopus bibliographical databases. High rate of suspicion and serological tests availability are of utmost importance in order to detect it and treat it successfully and promptly.

Características clínicas y epidemiologícas de la meningoencefalitis tuberculosa en menores de 14 años en edad. Hospital Belén de Trujillo 1984-2003 / Clinical and epidemiological characteristics of the tuberculous meningoencephalitis in patients younger than fourteen years old in Belen Hospital de Trujillo. 1984-2003

Con el objeto de conocer cuáles son las características clínicas y epidemiológicas de la meningoencefalitis tuberculosa en pacientes menores de 14 años hospitalizados en el Hospital Belén de Trujillo entre los años 1984 y 2003 se realizó un estudio descriptivo restrospectivo revisando historias clínicas de archivo, incluyendo en el estudio a 21 pacientes que tuvieron un puntaje según criterios de Stegen Y Toledo igual a mayor de 7 o características compatibles del líquido cefalorraquideo. El 55 por ciento fueron pacientes del sexo masculino, el 66,67 por ciento fueron desnutridos, el 80.95 por ciento de condición socioeconómica baja, el 57,14 por ciento procedieron de zona urbano marginal, el 80,95 por ciento tubieron contacto tuberculoso, el 57,14 por ciento habían sido vacunados con BCG PPD mayor de 10 mm en 52,38 por ciento radiografía de torax anormal en 23,80 por ciento y baciloscopía positiva de líquido cefalorraquídeo en 19,04 por ciento. Los hallazgos clínicos más frecuentes fueron: transtornos de conciencia (90,47 por ciento), fiebre (85,71 por ciento), hiporexia (80,95 por ciento), decaimiento (71,42 por ciento), signos meningeos (66,66 por ciento), deficit motor (57,14 por ciento) y cefalea (47,61). Se encontraron 2 pacientes fallecidos.

In order to know which are the clinical and epidemic characteristics of the tuberculous meningoencefalitis in patients under 14 years hospitalized in Trujillo's Belen Hospital between 1984 and 2003 it was carried out the descriptive restospective study analizing medical records, including 21 patients that has a score of 7 or higher according to Stegen and Toledo criterio. or compatible features of cerebrospinal fluid. 55 per cent were male, 66.67 per cent were undernourished, 80.95 per cent of low socioeconomic level, 57.14 per cent came from marginal urban area, 80.95 per cent had contact with tuberculosis, 57.14 per cent had been vaccinated with BCG PPD higher than 10 mm in 52.38 per cent abnormal x-ary of torax in 23.80 per cent and posiitive baciloscopía of cerebrospinal fluid in 19.04 per cent. The mots frequent clínical finding were: concientious dysfunction (90.47 per cent), fever (85.71 per cent), hyperoxia (80.95 per cent), malaise (71,42 per cent) meningeal signs (66,66 per cent) palsy (57, 14 per cent) and headache (47,61 per cent). 2 patients died (9,53 percent)