Epidemiologia de traumatismo craniencefálico em um hospital / Epidemiology of cranioencephalic trauma in a hospital

OBJETIVO: Analisar o perfil epidemiológico de vítimas de traumatismo craniencefálico. MÉTODOS: Estratificação de uma amostra de 4.466 pacientes com traumatismo craniencefálico de um hospital de Uberlândia (MG), entre 2010 e 2015, acordo com a ocorrência anual. Os pacientes foram divididos em grupos de idade e sexo, utilizando o Excel. RESULTADOS: Os homens foram as principais vítimas dos traumatismos craniencefálicos em todas as faixas etárias e em todos os anos analisados neste estudo, principalmente em idades inferiores a 40 anos. CONCLUSÃO: O sexo masculino e a idade até 40 anos tendem a ser fatores risco para o traumatismo craniencefálico. Os resultados desta análise podem justificar medidas de prevenção direcionadas para este grupo de risco, no sentido de reduzir a morbimortalidade.(AU)

OBJECTIVE: To analyze the epidemiological profile of cranioencephalic trauma (CET) patients. METHODS: Stratification of a sample of 4,466 patients with cranioencephalic trauma of a hospital in the city of Uberlândia, state of Minas Gerais, between 2010 and 2015, according to an yearly occurrence. The patients were divided in in age and gender groups, with the use of Excel. RESULTS: Men were the main victims of cranioencephalic trauma in all age groups and in all the years analyzed in this study, especially in the ages below 40 years. CONCLUSION: Males and ages up to 40 years tend to be at risk for cranioencephalic trauma. The results of this analysis may warrant prevention measures directed to this risk group to reduce morbidity and mortality.(AU)

Are the severe injuries of cutaneous leishmaniasis caused by an exacerbated Th1 response?

American tegumentary leishmaniasis (ATL) is a disease whose clinical features are strongly related to the type of immune response it induces. Herein we report an atypical presentation of cutaneous leishmaniasis in a woman with a severe and extensive sore located in her leg, and we describe the differences between the usual local immune response in ATL and the local immune response in this patient. We observed an intense inflammatory response characterized by Th1 cells and cytokines with conspicuous expression of Toll-like receptor 3 (TLR-3). Few parasites were present, but there was an extensive tissue damage. We also discuss the immunological factors that could be related to the atypical presentation.

[Transverse minilaparotomy as an access route in right colon disease: a valid alternative to midline laparotomy]. / La minilaparotomia trasversale come via di accesso nella patologia del colon destro: una valida alternativa alla laparotomia mediana.

AIMS OF THE STUDY: 1. To evaluate the feasibility and appropriateness of transverse right minilaparotomy for right colectomy and lymphadenectomy. 2. To identify the clinical advantages, if any, of this access route compared to the more traditional midline incision. PATIENTS: 44 patients with right colon adenocarcinoma undergoing colonic resection via a transverse or midline laparotomy. METHODS: The transverse incision starts 1 cm above the umbilicus, running from the midline to the anterior axillary line. RESULTS: 17 (39%) transverse minilaparotomies and 27 (51%) midline laparotomies were performed, respectively. The mean operative time was 107 min for patients with the transverse incision and 157 min. for those with midline laparotomy. Twelve out of 17 patients (70%) with the transverse incision experienced no or only mild pain as against 11 out of 27 patients (41%) with midline laparotomy. Bowel function was slightly faster in the first group of patients, though the difference was not statistically significant. Forty-seven percent of patients with transverse minilaparotomy were discharged within 8 days postoperatively as against 4% with midline laparotomy (P = 0.001). No major complications occurred in the first group, while 2 patients (7%) operated on via the midline laparotomy experienced complications (haemorrhage, deep venous thrombosis). CONCLUSION: Although this is a preliminary study in only 44 patients, our results support the idea that transverse minilaparotomy is a less traumatic access route to the right colon, in addition to offering an adequate exposure of the operative field, faster postoperative recovery and a shorter hospital stay. We believe it to be a good alternative to midline laparotomy for right colon surgery.