Assuntos
Pneumotórax , Edema Pulmonar , Drenagem , Humanos , Oxigênio/uso terapêutico , Edema Pulmonar/terapiaRESUMO
We studied 32 patients, aged 7 to 17 years, with clinical symptoms of perennial allergic rhinitis, isolated (n = 21) or associated with asthma (n = 11), all of them with positive skin test and specific serum IgE for Dermatophagoides pteronyssinus (Dpt). The control group consisted of 10 children aged 7 to 16 years, with no personal or family history of allergy and with negative skin tests and negative specific serum IgE for mites. Total and specific IgE measurements in nasal secretion and nasal provocation testing (NPT) were also performed with increasing concentrations of Dermatophagoides pteronyssinus (Dpt) extracts. The nasal response was evaluated using a clinical score and active anterior rhinomanometry. The levels of total and specific IgE in nasal secretion were higher in patients with allergic rhinitis than in individuals from the control group. The NPT presented a significant correlation with clinical symptoms, skin tests and specific serum IgE. None of the individuals from the control group presented a positive NPT. No generalized reactions or bronchial response at the immediate phase of NPT were observed. The NPT constitutes a safe, dependable investigative procedure of nasal reactivity to a specific allergen, presenting a good sensitivity and specificity when compared to the other methods classically used in allergy studies.
Assuntos
Testes de Provocação Nasal , Rinite Alérgica Perene/diagnóstico , Adolescente , Alérgenos/imunologia , Antígenos de Dermatophagoides , Criança , Glicoproteínas/imunologia , Humanos , Imunoglobulina E/análise , Manometria , Mucosa Nasal/imunologia , Mucosa Nasal/metabolismo , Testes de Provocação Nasal/estatística & dados numéricos , Valor Preditivo dos TestesRESUMO
The protective role of salivary IgA in dental caries has not been completely demonstrated, so, in order to elucidate this point, we evaluated 15 totally and partially IgA-deficient children in terms of the following variables: dental caries indexes, bacterial plaques, number of Streptococcus mutans and Lactobacillus in the saliva, and titers of IgA, IgG and IgM anti-Streptococcus mutans antibodies in the saliva. Age-matched healthy children served as the control group. IgA-deficient children showed caries scores lower than those of the healthy children; in addition, no statistical difference was found between amount of dental plaque and numbers of the bacteria in saliva. The totally IgA-deficient children presented IgM in levels much higher than the healthy children (p < 0.05). These data could indicate a compensation for the IgA deficiency by IgM.
