[Functional results after shoulder hemiarthroplasty for proximal humerus fracture: experience in our center]. / Resultados funcionales tras hemiartroplastía de hombro por fractura de húmero proximal: experiencia en nuestro centro.

INTRODUCTION: shoulder hemiarthroplasty is being relegated as a treatment for non-osteosynthetic proximal humerus fractures. Our objective is to analyze the functional results of patients treated with hemiarthroplasty for this reason in our hospital. MATERIAL AND METHODS: cross-sectional descriptive study that includes patients operated between February 2016 and November 2021; 24 patients, with an average follow-up of 44.6 months. Active joint balance, the Constant-Murley test, the DASH questionnaire and current pain (VAS) were collected. The radiographic parameters analyzed were the number of fracture fragments and the consolidation of the tuberosities. RESULTS: a mean of 71.65 ± 13.75 was obtained in the Constant-Murley and 18.14% ± 13.92 in the DASH. For shoulder flexion, the mean was 108.75° ± 41.26; 104.5° ± 43.68 for abduction and 33° ± 14.73 for external rotation. About internal rotation, 60% of the patients reached the scapular plane. Average VAS was 1.25 ± 1.74. Consolidated tuberosities in 90.5%. There were no significant differences comparing the Constant-Murley test, DASH or rotations between both, over and under 65 years old group of patients. Those over 65 years of age obtained a mean flexion of 125.91° ± 26.82 whereas those under 87.78° ± 26.82 (p = 0.038). The mean abduction in those over 65 was 125.45 ± 28.94 vs 78.89 ± 46.29 in the young group (p = 0.012). CONCLUSION: hemiarthroplasty provides quality of life with acceptable functionality and good pain control, therefore it should continue to be an alternative to consider in selected patients.

INTRODUCCIÓN: la hemiartroplastía de hombro está siendo relegada como tratamiento de fracturas de húmero proximal no osteosintetizables. Nuestro objetivo es analizar los resultados funcionales de los pacientes tratados con hemiartroplastía por este motivo en nuestro centro. MATERIAL Y MÉTODOS: estudio descriptivo transversal que incluye a los pacientes intervenidos entre Febrero de 2016 y Noviembre de 2021; 24 pacientes, con un seguimiento medio de 44.6 meses. Fueron recogidos el balance articular activo, el test de Constant-Murley, el cuestionario DASH y el dolor actual (EVA). Como parámetros radiográficos se analizó el número de fragmentos de fractura y la consolidación de las tuberosidades. RESULTADOS: se obtuvo una media de 71.65 ± 13.75 en el Constant-Murley y de 18.14% ± 13.92 en el DASH. Para flexión de hombro la media fue de 108.75° ± 41.26; 104.5° ± 43.68 para abducción y 33° ± 14.73 para rotación externa. En rotación interna 60% llegaba hasta plano interescapular. EVA medio de 1.25 ± 1.74. Tuberosidades consolidadas en 90.5%. No hubo diferencias significativas entre el Constant-Murley, DASH ni rotaciones de pacientes mayores y menores de 65 años. Los mayores de 65 años obtuvieron flexión media de 125.91° ± 26.82 y los menores de 87.78° ± 26.82 (p = 0.038). La abducción media en mayores de 65 fue de 125.45 ± 28.94 versus 78.89 ± 46.29 en el grupo joven (p = 0.012). CONCLUSIÓN: la hemiartroplastía otorga calidad de vida con aceptable funcionalidad y buen control del dolor, por lo que debe continuar siendo una alternativa a tener en cuenta en pacientes seleccionados.

Síndrome de Alicia en el País de las Maravillas como primera y única manifestación de un ictus isquémico / Alice in Wonderland syndrome as the initial and sole manifestation of ischaemic stroke

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Infectious complications related to external ventricular shunt. Incidence and risk factors. / Complicaciones infecciosas relacionadas con el drenaje ventricular externo. Incidencia y factores de riesgo.

OBJECTIVE: Infectious complications related to external ventricular shunt (ICREVS) are a main problem in neurocritical intensive care units (ICU). The aim of the review is to assess the incidence of ICREVS and to analyse factors involved. METHODS: Retrospective analysis, adult polyvalent ICU in a third level reference hospital. Patients carrying external ventricular shunt (DVE) were included. Those patients with central nervous system infection diagnosed prior DVE placement were excluded. RESULTS: 87 patients were included with 106 DVE. Most common admittance diagnosis was subarachnoid haemorrhage (49.4%). 31 patients with 32 DVE developed an ICREVS. Infection rate is 19.5 per 1000 days of shunt for ICREVS and 14 per 1000 days for ventriculitis. 31.6% of the patients developed ICREVS and 25.3% ventriculitis. Patients who developed ICREVS presented higher shunt manipulations (2.0 ± 0.6 vs. 3.26 ± 1.02, p=0.02), shunt repositioning (0.1 ± 0.1 vs. 0.2 ± 0.1) and ICU and hospital stay (29.8 ± 4.9 vs 49.8 ± 5.2, p<0.01 y 67.4 ± 18.8 vs. 108.9 ± 30.2, p=0.02. Those DVE with ICREVS were placed for longer not only at infection diagnosis but also at removal (12.6 ± 2.1 vs. 18.3 ± 3.6 and 12.6 ± 2.1 vs. 30.4 ± 7.3 days, p<0.01). No difference in mortality was found. CONCLUSIONS: One out of three patients with a DVE develops an infection. The risk factors are the number of manipulations, repositioning and the permanency days. Patients with ICREVS had a longer ICU and hospital average stay without an increase in mortality.

[Validity of airway predictors in outpatient medicine]. / Validez de los predictores de vía aérea difícil en medicina extrahospitalaria.

Isolation of the airway sometimes determines the survival or death of the patient. To anticipate the presence of a difficult airway (DA) there are a number of indicators that are validated for hospitals: Mallampati, sternum and thyromental distance, interdental distance and Cormack grade. The aim of this study is to evaluate the use of these indicators in the ambulatory setting and to know the incidence of DA. This data was collected from 324 intubations. Most patients were males (65.2%). The average age of the population was 63 years and no significant difference in age between DA and DA was found. A DA presence of 20.7% was objectified and an alternative device utilization of 21.4%. The thyromental distance was abnormal in 59% of patients and sternomentonal distance in 56.4% but neither showed an association with the presence of DA (p = 0.681 and p = 0.415 respectively). Interdental distance was less than 3 cm if presence is associated with DA (p = 0.005). The sensitivity and specificity of all measures are low. According to our series the sternum and thyromental distance are not useful in the ambulatory setting, but interdental distance is useful for predicting a DA.

Disartria y mareo persistente con estudio neurológico previo: hasta dónde seguir investigando / Acute persistent dysarthria and dizziness with previous neurogical study: is it enough to establish a diagnosis?

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[Recurring neuromyelitis without optic neuritis: a case report]. / Neuromielitis recidivante sin neuritis optica: a proposito de un caso.

INTRODUCTION: Neuromyelitis optica, or Devic's disease, is an inflammatory, demyelinating disease of the central nervous system that selectively affects the optic nerves and the spinal cord, with a high rate of relapses. Anti-aquaporin-4 (AQP4) antibodies are a highly specific marker for this condition. CASE REPORT: A 66-year-old female with longitudinally extensive dorsal transverse myelitis with complete remission following steroidal treatment and later acute relapse, with palsy in one limb. The differential diagnoses considered included a spinal tumour and arteriovenous malformation of the spinal cord. Being positive for AQP4 was the decisive factor in the final diagnosis. CONCLUSIONS: Early detection of anti-AQP4 antibodies together with appropriate immunotherapy can be the key to a better prognosis. An early diagnosis is essential to be able to start treatment at an early stage and thus prevent relapses and severe sequelae.

Infarto cerebral tras quimioterapia con cisplatino-gemcitabina: probable causa-efecto / Cerebral infarction after cisplatin-gemcitabine chemotherapy: probable cause-effect

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Migraine and hypercoagulable states in ischemic stroke.

BACKGROUND: Whether migraine is associated with a higher prevalence of hypercoagulable states (HS) in ischemic stroke patients is unknown. METHODS: This was a prospective study of patients under 55 years of age with brain ischemia. A systematic questionnaire addressed the antecedent of migraine with aura (MA) or without aura (MO). We investigated the presence of HS by an extensive battery of haematological tests. The presence of patent foramen ovale (PFO) was assessed by trans-oesophageal echocardiography. RESULTS: A total of 154 patients (95 men; mean ± SD age, 44.12 ± 8.4 years) were included; 44 had migraine, 15 had MA. HS were more frequent in the migraine than non-migraine group (38.6% vs. 16.4%, p < 0.01). The multivariate analysis showed that MO was associated with a 2.88-fold (95% CI, 1.14 to 7.28) increased risk of HS diagnosis. However, in the group of patients with brain infarction under 50 years old, MA, but not MO, was independently associated with HS (OR 6.81; 95% CI, 1.01 to 45.79). CONCLUSION: In young patients with ischemic stroke, migraine may be associated with a higher frequency of HS.

[Restless legs syndrome. Features and impact on sleep]. / Síndrome de piernas inquietas. Características e impacto sobre el sueño.

INTRODUCTION: Restless legs syndrome (RLS) is a chronic neurological disorder that has a negtive influence on sleep. We describe clinical spectrum, polysomnogram and impact on sleep of patients' series with RLS. METHODS: We studied 49 patients with RLS. We analyse socio- demographic information, clinical features, therapy and impact on sleep. We realized differents questionnaire: Index of Severity of Sleep, Epworth Scale, Index-RLS, Questionnaire Quality of Life-RLS and Questionnaire from limitation of laboral productivity. RESULTS: Mean age is 60.33+/-14.27 with similar distribution enter gender. They presented a positive family history in 36,73% with predominant in early onset of symptoms. Secondary causes more frequent associated were rheumatoid arthritis, iron-deficiency, uremia, pregnancy and polineuropathy. Significative prevalence of insomnia (73,43%) and periodic limb movement disorder (51,02%), obstructive sleep apnea syndrome (22,45%) and hipersomnia (22,45 %). Pharmacological treatment more used were dopaminergic drugs. We didn't find significant stadistic differences enter clinical feature and therapy, so tendency to better quality of life with dopaminergic drugs. CONCLUSIONS: It's an neurological disorder with important delay in diagnosis. Early detection is needed because important impact on sleep efficiency and quality of life, and improvement with therapy, solely dopaminergic drugs.

[Opsoclonus-myoclonus-ataxia syndrome: two anatomo-clinical case reports]. / Sindrome opsoclono-mioclono-ataxia: dos casos anatomoclinicos.

INTRODUCTION: Opsoclonus-myoclonus-ataxia syndrome (OMAS) is characterised by the acute or subacute development of chaotic eye movements and diffuse myoclonus. On some occasions it is associated with ataxia and encephalopathy. In adults there are multiple causations and a possible paraneoplastic origin must always be taken into account. CASE REPORTS: We report two cases of OMAS of a paraneoplastic origin with a post mortem study. In the first case, the syndrome was associated to a small-cell carcinoma in the lungs, and in the second patient it was associated to a digestive lymphoma. Neuroimaging studies did not reveal any kind of alterations in either of the two cases. In our cases, none of the antibodies that are relatively frequently associated to this syndrome were found. In both of them, an immunomodulator treatment regimen was established; only the patient with the lymphoma showed an initial improvement with antineoplastic therapy. In the pathological study, alterations were observed in the brain stem, and in the second patient alterations were also found in the cerebellum. CONCLUSIONS: This is a rare condition that obliges the specialist to think in order to reach a correct diagnosis, and to search for the primary tumour and establish early treatment in order to bring about an improvement and even the remission of the neurological signs and symptoms. The pathological findings are not pathognomonic, but they are typical of this syndrome.

Síndrome opsoclono-mioclono-ataxia: dos casos anatomoclínicos / Opspclonus. Myoclonuz-ataxia syndrome: Two anatomo-clinical case reports

Introducción. El síndrome opsoclono-mioclono-ataxia (SOMA) se caracteriza por el desarrollo agudo o subagudode movimientos oculares caóticos y mioclono difuso. En algunas ocasiones, asocia ataxia y encefalopatía. En el adulto existen múltiples etiologías, y hay que tener siempre en cuenta el posible origen paraneoplásico. Casos clínicos. Presentamos dos casos de SOMA de origen paraneoplásico con estudio post mortem. En el primer caso, el síndrome se asoció a un carcinomade células pequeñas de pulmón, y en el segundo paciente a un linfoma digestivo. Los estudios de neuroimagen no mostraron alteraciones en ninguno de los dos casos. No se descubrió en nuestros casos ninguno de los anticuerpos asociados con relativa frecuencia a este síndrome. En ambos se pautó tratamiento inmunomodulador; únicamente el paciente con linfoma mejoró inicialmente con el tratamiento antineoplásico. En el estudio anatomopatológico se observaron alteraciones en el tronco del encéfalo, y en el segundo paciente también en el cerebelo. Conclusión. Se trata de una entidad rara, en la que hay que pensar para lograr un diagnóstico correcto, búsqueda del tumor primario y su tratamiento precoz, con el fin de producir mejoría e inclusoremisión del cuadro neurológico. Los hallazgos anatomopatológicos no son patognomónicos, pero sí típicos de este síndrome

Introduction. Opsoclonus-myoclonus-ataxia syndrome (OMAS) is characterised by the acute or subacute development of chaotic eye movements and diffuse myoclonus. On some occasions it is associated with ataxia and encephalopathy. In adults there are multiple causations and a possible paraneoplastic origin must always be taken into account. Case reports. Wereport two cases of OMAS of a paraneoplastic origin with a post mortem study. In the first case, the syndrome was associated to a small-cell carcinoma in the lungs, and in the second patient it was associated to a digestive lymphoma. Neuroimaging studies did not reveal any kind of alterations in either of the two cases. In our cases, none of the antibodies that are relativelyfrequently associated to this syndrome were found. In both of them, an immunomodulator treatment regimen was established; only the patient with the lymphoma showed an initial improvement with antineoplastic therapy. In the pathological study, alterations were observed in the brain stem, and in the second patient alterations were also found in the cerebellum. Conclusions. This is a rare condition that obliges the specialist to think in order to reach a correct diagnosis, and to search forthe primary tumour and establish early treatment in order to bring about an improvement and even the remission of the neurological signs and symptoms. The pathological findings are not pathognomonic, but they are typical of this syndrome

Síndrome de piernas inquietas. Características e impacto sobre el sueño / Restless legs síndrome. Features and impacto on sleep

Introducción. El síndrome de piernas inquietas (SPI) es un trastorno neurológico crónico que afecta de forma negativa al sueño. El objetivo principal es determinar las características clínicas, polisomnográficas, la eficacia de los tratamientos empleados y el impacto sobre el sueño de una serie de pacientes. Métodos. Estudiamos 49 pacientes con SPI. Se recoge información sociodemográfica, datos clínicos y polisomnográficos, tratamientos empleados y el impacto sobre el sueño. Se realizaron diferentes encuestas: índice de severidad de sueño (ISS), escala de Epworth, cuestionario de evaluación sobre el SPI (IRLS), cuestionario de calidad de vida del SPI (QoL-RLS) y cuestionario sobre la limitación de la productividad laboral (LPL). Resultados. La edad media es de 60,33±14,27 años, con distribución por sexos similar. Presentan una historia familiar positiva el 36,73 %, con predominio en el grupo de inicio precoz de los síntomas. Las causas secundarias más frecuentemente asociadas son la artritis reumatoide, ferropenia, uremia, embarazo y polineuropatía. Prevalencia significativa del insomnio (73,47%) y de los movimientos periódicos de extremidades (MMPE) (51,02%), y también síndrome de apnea obstructiva del sueño (22,45%) e hipersomnia (22,45%). El tratamiento farmacológico más empleado son los agonistas dopaminérgicos. No encontramos diferencias estadísticamente significativas entre la evolución clínica y el tratamiento empleado, aunque una tendencia a mejor calidad de vida con agonistas dopaminérgicos. Conclusiones. Se trata de una enfermedad con un tiempo de demora en el diagnóstico nada desdeñable. Tiene gran importancia su detección precoz dado el impacto que produce sobre la eficiencia del sueño y la calidad de vida, y la eficacia que demuestran los tratamientos empleados, fundamentalmente los agonistas dopaminérgicos (AU)

Introduction: Restless legs syndrome (RLS) is a chronic neurological disorder that has a negtive influence on sleep. We describe clinical spectrum, polysomnogram and impact on sleep of patients' series with RLS. Methods: We studied 49 patients with RLS. We analyse socio- demographic information, clinical features, therapy and impact on sleep. We realized differents questionnaire: Index of Severity of Sleep, Epworth Scale, Index-RLS, Questionnaire Quality of Life-RLS and Questionnaire from limitation of laboral productivity. Results: Mean age is 60.33+/-14.27 with similar distribution enter gender. They presented a positive family history in 36,73% with predominant in early onset of symptoms. Secondary causes more frequent associated were rheumatoid arthritis, iron-deficiency, uremia, pregnancy and polineuropathy. Significative prevalence of insomnia (73,43%) and periodic limb movement disorder (51,02%), obstructive sleep apnea syndrome (22,45%) and hipersomnia (22,45 %). Pharmacological treatment more used were dopaminergic drugs. We didn't find significant stadistic differences enter clinical feature and therapy, so tendency to better quality of life with dopaminergic drugs. Conclusions: It's an neurological disorder with important delay in diagnosis. Early detection is needed because important impact on sleep efficiency and quality of life, and improvement with therapy, solely dopaminergic drugs (AU)

Contribución al estudio de la contractilidad del suelo pélvico / Contribution to the pelvic floor contractility analysis

Objetivo. Realizar un estudio instrumental tonimétrico de la contractilidad del suelo pélvico (elemento que creemos podría ser necesario en el mantenimiento de sus funciones fisiológicas normales) y su correlación con distintos parámetros. Material y método. Cumplimentación de un cuestionario y realización de un examen ginecológico que incluye una tonimetría perineal para la recogida de las variables del estudio. Comparación estadística de la fuerza muscular entre dos poblaciones similares, con la única diferencia de que una de ellas se encontraba en posparto inmediato. Además, se trató de correlacionar este parámetro con distintas variables: edad, índice de masa corporal (IMC), práctica deportiva y distintos factores ginecoobstétricos. Resultados. La media de la fuerza muscular en ambos grupos es similar y se sitúa por encima de la media de referencia. Por el contrario, no es suficiente para realizar un correcto bloqueo perineal al esfuerzo (sobre todo en la población en posparto inmediato). No existe correlación entre las variables estudiadas y la fuerza muscular del suelo pélvico en ninguna de las dos poblaciones. Conclusiones. El parto no está relacionado, en modo alguno, con la fuerza de contracción del suelo pélvico, y se muestra como un parámetro totalmente independiente. Este hecho, unido a la imposibilidad de buena parte de la población (incluso joven y asintomática) de realizar un correcto bloqueo perineal, nos lleva a afirmar que no tiene ningún sentido realizar en el posparto la tan extendida reeducación del suelo pélvico basada, prioritariamente o de forma exclusiva, en la mejora de la fuerza muscular del mismo

Aim. To perform an instrumental study (tonimetric test) of the pelvic floor contractility (element that we consider may be necessary for the maintenance of its normal physiological functions) and its correlation with different parameters. Material and method. To fill out a questionnaire together with a gynecological examination that includes a perineal tonimetric test in order to collect the study variables. Statistical comparison of muscular strength in two similar patient groups, with the only difference that one of them is composed of women in immediate postpartum period. In addition, a correlation was performed between this parameter and some different variables such as body mass index (BMI), sports activity and several gynecological factors. Results. Mean muscular strength in both patient groups is similar and above the mean reference. Nevertheless, it is not high enough to achieve correct perineal blockage with stress (especially among patients in immediate postpartum period). There is no correlation between any of the variables studied and pelvic floor muscular strength in either of the patient groups. Conclusions. Partum and strength of contraction of pelvic floor are not related in any case and must be considered as totally independent variables. This fact, together with the impossibility for the majority of the population (even for young and asymptomatic individuals) to perform correct perineal blockage, has led us to conclude that there is no reason to use the so extended practice of pelvic floor re-education as a priority treatment or exclusive one for muscular strength enhancement during the postpartum period

[Effectiveness of a programme of intensive tobacco counselling by nursing professionals]. / Efectividad de un programa de consejo antitabaco intensivo realizado por profesionales de enfermería.

OBJECTIVE: To determine the effectiveness of a systematic intensive tobacco counselling programme conducted by nursing professionals. DESIGN: Randomised clinical trial with control. SETTING: Primary care nursing and medical consultations. PARTICIPANTS: Smokers requesting help in our centre's medical clinics during the recruitment period, up to the sample size required (125). Inclusion criteria were: aged between 18 and 70, people who smoked during the preceding month any number of cigarettes a day, and a score over 7 on the Richmond test. INTERVENTIONS: The patients recruited were randomised, according to the clinic from which they came, to the group that received brief counselling from the doctor (control group) or to the group that received brief counselling plus nursing follow-up (intervention group). Follow-up visits were programmed in this latter group for up to 3 months after giving up smoking. MAIN MEASUREMENTS: Abstinence at 12 and 24 months. RESULTS: The effectiveness of the intervention considered as the rate of abstinence at 12 months was 13.8% (95% CI, 6.5-24.7) in the control group and 6.7% (95% CI, 1.8-16.2) in the intervention group, with no significant differences between the two. CONCLUSIONS: In smokers seen in primary care, the effectiveness of a programme of intensive tobacco counselling by nursing staff is no more effective than the doctor's brief, one-off counselling. Brief counselling has a better cost-effectiveness relationship than intensive counselling.

Efectividad de un programa de consejo antitabaco intensivo realizado por profesionales de enfermería

Objetivo. Determinar na efectividad de un programa de consejo antitabaco intensivo, sistemático, realizado por profesionales de enfermería. Diseño. Ensayo clínico controlado y aleatorizado. Emplazamiento. Consultas de medicina y enfermería de atención primaria. Participantes. Fumadores que demandaron asistencia en las consultas de medicina de nuestro centro durante el período de captación, hasta alcanzar el tamaño muestral requerido (125 pacientes). Los criterios de inclusión fueron: edad entre 18 y 70 años, personas que fumaron diariamente durante el último mes cualquier cantidad de cigarillos y puntuación del test de Richmond > 7. Intervenciones. Los pacientes captados se asignaron de forma aleatoria, según la consulta de la que procedían, al grupo que recibía consejo breve por parte del médico (grupo control) o al grupo que recibía consejo breve más seguimiento por enfermería (grupo intervención). En este grupo se programaron visitas de seguimiento hasta 3 meses después de dejar de fumar. Mediciones principales. Abstinencia a los 12 y 24 meses. Resultados. La efectividad de la intervención, considerada como la tasa de abstinencia a los 12 meses, fue del 13,3 por ciento (intervalo de confianza [IC] del 95 por ciento, 6,5-24,7) en el grupo control y del 6,7 por ciento (IC del 95 por ciento, 1,8-16,2 en el grupo intervención, sin diferencias significativas entre ellos. Conclusiones. La efectividad de un programa de consejo antitabaco intensivo realizado por enfermería no es más efectivo que el consejo breve aislado del médico en fumadores atendidos en atención primaria. El consejo breve tiene una mejor relación coste-efectividad que el intensivo.(AU)