RESUMO
Langerhans cell histiocytosis (LCH) is a rare disorder defined by the abnormal proliferation of Langerhans cells. While LCH can present at any age, it is classically described as a pediatric condition, and is therefore overlooked in the adult patient. Additionally, depending on tumor burden and location, LCH can manifest with a host of oral and systemic symptoms which further confuses the clinical presentation and ultimate diagnosis.The authors present a unique report of an elderly Hispanic male diagnosed with mandibular LCH who sought primary tumor excision after neoadjuvant chemotherapy. In this study, a fibula-free flap was used for subsequent reconstruction.The purpose of the study is 2-fold: to highlight the variability of LCH in both patient symptomatology and demographics, as well as the role of plastic reconstructive surgery in definitive LCH management, particularly in the setting of single system unifocal disease.
Assuntos
Histiocitose de Células de Langerhans/diagnóstico por imagem , Histiocitose de Células de Langerhans/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Doenças RarasRESUMO
The study of the lymphatic system has a lengthy history, with many notable medical minds making important contributions. We now appreciate that this system is an essential component of the immune system, as well as vital to the maintenance of fluid homeostasis within the body. A good knowledge of the lymphatic system is clinically important concerning cancer, edema, surgery, and the immune response. This article reviews the history of the evolution and discovery of the lymphatic system.
Assuntos
Anatomia/história , Sistema Linfático/anatomia & histologia , História do Século XVI , História do Século XVII , História do Século XVIII , História do Século XIX , História do Século XX , História Antiga , HumanosRESUMO
This review focuses on how the study of anatomy in India has evolved through the centuries. Anatomical knowledge in ancient India was derived principally from animal sacrifice, chance observations of improperly buried human bodies, and examinations of patients made by doctors during treatment. The Vedic philosophies form the basis of the Ayurvedic tradition, which is considered to be one of the oldest known systems of medicine. Two sets of texts form the foundation of Ayurvedic medicine, the Susruta Samhita and the Charaka Samhita. The Susruta Samhita provided important surgical and anatomical information of the understanding of anatomy by Indians in the 6th century BCE. Here we review the anatomical knowledge known to this society.
