Effects of weight loss on dynamic hyperinflation in obese women asthmatics.

Obese adults with asthma are more likely to develop dynamic hyperinflation (DH) and expiratory flow limitation (EFL) than nonobese asthmatics, and weight-loss seems to improve the breathing mechanics during exercise. However, studies evaluating the effect of weight loss on DH in obese adults with asthma have not been performed. We sought to evaluate the effect of a weight loss program on DH in obese adults with asthma. Forty-two asthma patients were enrolled in a weight loss program (diet, psychological support, and exercise) and were subsequently divided into two groups according to the percentage of weight loss: a ≥5% group ( n = 19) and a <5% group ( n = 23). Before and after the intervention, DH and EFL (constant load exercise), health-related quality of life (HRQoL), asthma control, quadriceps muscle strength and endurance, body composition, and lung function were assessed. Both groups exhibited a decrease of ≥10% in inspiratory capacity (DH) before intervention, and only the ≥5% group showed clinical improvement in DH compared with the <5% group postintervention (-9.1 ± 14.5% vs. -12.5 ± 13.5%, respectively). In addition, the ≥5% group displayed a significant delay in the onset of both DH and EFL and a clinically significant improvement in HRQoL and asthma control. Furthermore, a correlation was observed between reduced waist circumference and increased inspiratory capacity ( r = -0.45, P = 0.05) in the ≥5% group. In conclusion, a weight-loss of ≥5% of the body weight improves DH, which is associated with waist circumference in obese adults with asthma. In addition, the group with greater weight-loss showed a delayed onset of DH and EFL during exercise and improved asthma clinical control and HRQoL. NEW & NOTEWORTHY This is the first study to evaluate dynamic hyperinflation (DH) after a weight loss program in obese patients with asthma. Our results demonstrate that moderate weight loss can improve DH in obese patients with asthma that is associated with a decrease in abdominal fat. Moreover, a minimum of 5% in weight loss delays the onset of DH and expiratory flow limitation besides inducing a clinical improvement in asthma quality of life and clinical control.

Exercise Improves Physical Activity and Comorbidities in Obese Adults with Asthma.

INTRODUCTION: Obese adults with asthma have an increased number of comorbidities and reduced daily life physical activity (DLPA), which may worsen asthma symptoms. Exercise is recommended to improve asthma outcomes; however, the benefits of exercise for psychosocial comorbidities and physical activity levels in obese adults with asthma have been poorly investigated. OBJECTIVE: This study aimed to assess the effects of exercise on DLPA, asthma symptoms, and psychosocial comorbidities in obese adults with asthma. METHODS: Fifty-five grade II obese adults with asthma were randomly assigned to either a weight loss program + exercise program (WL + E group, n = 28) or a weight loss program + sham (WL + S group, n = 27). The WL + E group incorporated aerobic and resistance muscle training into the weight loss program (nutrition and psychological therapies), whereas the WL + S group performed breathing and stretching exercises. DLPA, asthma symptoms, sleep quality, and anxiety and depression symptoms were quantified before and after treatment. RESULTS: After 3 months, the WL + E group presented a significant increase in daily step counts (3068 ± 2325 vs 729 ± 1118 steps per day) and the number of asthma symptom-free days (14.5 ± 9.6 vs 8.6 ± 11.4 d·month) compared with the WL + S group. The proportion of participants with improvements in depression symptoms (76.4% vs 16.6%) and a lower risk of developing obstructive sleep apnea (56.5% vs 16.3%) was greater in the WL + E group than that in the WL + S group (P < 0.05). Significant improvements in sleep efficiency (6.6% ± 5.1% vs 1.3% ± 4.7%) and latency (-3.7 ± 5.9 vs 0.2 ± 5.6 min) were also observed in the WL + E group. CONCLUSIONS: Our results strongly suggest that exercise training plus a weight loss program improves DLPA, sleep efficiency, and depression and asthma symptoms in obese adults with asthma.

Dynamic hyperinflation and exercise limitations in obese asthmatic women.

Obese individuals and patients with asthma can develop dynamic hyperinflation (DH) during exercise; however, no previous study has investigated DH as a factor associated with reduced exercise capacity in obese asthmatic women. The aim of the present study was to examine the occurrence of DH and exercise limitations in obese asthmatics. Obese grade II [obese group (Ob-G); BMI 35-39.9 kg/m2; n=36] and nonobese [nonobese group (NOb-G); BMI 18.5-29.9 kg/m2; n=18] asthmatic patients performed a cardiopulmonary test to quantify peak V̇o2 and a submaximal exercise test to assess DH. Anthropometric measurements, quadriceps endurance, and lung function were also evaluated. A forward stepwise regression was used to evaluate the association between exercise tolerance (wattage) and limiting exercise factors. Fifty-four patients completed the protocol. The Ob-G (n = 36) presented higher peak V̇o2 values but lower power-to-weight ratio values than the NOb-G (P <0 .05). DH was more common in the Ob-G (72.2%) than in the NOb-G (38.9%, P < 0.05). The Ob-G had a greater reduction in the inspiratory capacity (-18 vs. -4.6%, P < 0.05). Exercise tolerance was associated with quadriceps endurance (r = 0.65; p<0.001), oxygen pulse (r = 0.52; p=0.001), and DH (r = -0.46, P = 0.005). The multiple regression analysis showed that the exercise tolerance could be predicted from a linear association only for muscular endurance (r = 0.82 and r2 = 0.67). This study shows that dynamic hyperinflation is a common condition in obese asthmatics; they have reduced fitness for activities of daily living compared to nonobese asthmatics. However, peripheral limitation was the main factor associated with reduced capacity of exercise in these patients.NEW & NOTEWORTHY This is the first study to investigate the occurrence of dynamic hyperinflation (DH) in obese asthmatics. Our results demonstrate that obese asthmatics present a higher frequency and intensity of DH than nonobese asthmatics. We also show that physical deconditioning in this population is linearly associated with cardiac (O2 pulse), respiratory (DH), and peripheral muscle (resistance) limitation. However, multiple linear regression demonstrated that peripheral muscle limitation may explain the exercise limitation in this population.

Validade de medidas autorreferidas de massa e estatura e seu impacto na estimativa do estado nutricional pelo índice de massa corporal / Validity of self-reported measures of weight and height and its impact on nutritional status prediction by body mass index

Introdução: medidas autorreferidas de massa e estatura têm sido utilizadas para avaliação do estado nutricional em estudos epidemiológicos. Objetivo: verificar a validade da massa e da estatura autorreferidas, bem como do índice de massa corporal (IMC) obtido com estes valores. Método: participaram 395 homens e 549 mulheres . Os dados foram coletados entre estudantes da Universidade Santa Cecília - Santos. Todos os sujeitos referiam a sua massa e estatura, para a realização das medidas em seguida.Utilizou-se o teste t de Student para amostras dependentes para comparação das médias, a correlação linear de Pearson (r) e Coeficiente de Correlação Intraclasse (R) entre as duas formas de obtenção dos resultados. Resultados: os homens autorreferiram de forma válida tanto sua massa (p=0,125; r=0,963; R=0,912) quanto sua estatura (p=0,058; r=0,974; R=0,921), validando a avaliação do estado nutricional. Já as mulheres tenderam a subestimar sua massa corporal (p=0,000; r=0,882; R=0,888) e superestimar sua estatura (p=0,000; r=0,854; R=0,814), causando subestimativa no valor de IMC. Conclusão: para o grupo estudado não seria válido utilizar as medidas autorreferidas de massa e estatura das mulheres para estimativa do seu estado nutricional pelo índice de massa corporal.(AU)

INTRODUCTION: the nursing staff must inform parents with children suffering from congenital heart defects regarding their needs related to this situation. The most common needs are the seven, as follows: Information related to cardiopathy, promotion of physical activities, adequate diet, care with buccal health, prevention of infectious endocarditis, care during cyanosis crisis and drug administration. OBJECTIVE: to characterize how much information these parents have regarding this disorder. METHOD: systematic mapping on the literature in MEDLINE, Cochrane, CINAHL, LILACS and SciELO databases, from 1997 to 2007, obtaining 17 papers. RESULTS: the following needs, cyanosis crisis, promotion of physical activities and drug administration, were not adequately studied. The majority amongst the 17 papers was concentrated on the remaining four needs. Beside this, parent's knowledge is not satisfactory and is fragmented. It happens either in developed countries as well as in the underdeveloped ones. In general, care is performed by nurses, dental physicians and physicians. Training programs for parents are scarce and only one is described as successful. Changes are mandatory in terms of reorganization of services involving training and support for parents. Besides, validation of programs and protocols of care to promote training and development is required. These programs must be flexible to allow adaptation to clinical situation and to social, cultural and economic determinant factors acting on the family.(AU)

Validade de medidas autorreferidas de massa e estatura e seu impacto na estimativa do estado nutricional pelo índice de massa corporal / Validity of self-reported measures of weight and height and its impact on nutritional status prediction by body mass index

Introdução: medidas autorreferidas de massa e estatura têm sido utilizadas para avaliação do estado nutricional em estudos epidemiológicos. Objetivo: verificar a validade da massa e da estatura autorreferidas, bem como do índice de massa corporal (IMC) obtido com estes valores. Método: participaram 395 homens e 549 mulheres . Os dados foram coletados entre estudantes da Universidade Santa Cecília - Santos. Todos os sujeitos referiam a sua massa e estatura, para a realização das medidas em seguida.Utilizou-se o teste t de Student para amostras dependentes para comparação das médias, a correlação linear de Pearson (r) e Coeficiente de Correlação Intraclasse (R) entre as duas formas de obtenção dos resultados. Resultados: os homens autorreferiram de forma válida tanto sua massa (p=0,125; r=0,963; R=0,912) quanto sua estatura (p=0,058; r=0,974; R=0,921), validando a avaliação do estado nutricional. Já as mulheres tenderam a subestimar sua massa corporal (p=0,000; r=0,882; R=0,888) e superestimar sua estatura (p=0,000; r=0,854; R=0,814), causando subestimativa no valor de IMC. Conclusão: para o grupo estudado não seria válido utilizar as medidas autorreferidas de massa e estatura das mulheres para estimativa do seu estado nutricional pelo índice de massa corporal.