[Combined treatment of recurrent ovarian cancer using citoreductive surgery and intraoperative hypertermical introabdominal hyper fusion].

This article analyses results of combined treatment of 40 female patients' age 28-73 (average 55) years with recurrent ovarian cancer who were treated in the Lviv state oncologist regional medically-diagnostic center from 2008 to 2010 year, using citoreductial interferes and introoperational pyrexias introabdominal hyper fusion.

[Resection of the liver combined with chemotherapy for the optimization of treatment in patients with metastatic colorectal cancer].

Anatomic hepatic resection is considered now a "gold standard" in the treatment of patients, suffering metastatic colorectal cancer (CRR) because it secures 23-35% survival solely and 35-58% in combination with chemotherapy. The immediate results of cornbined treatment and its impact on survival of patients, suffering CRR with hepatic metastases, were studied up. In Lvivskiy Oncological Centre and Zaporizhskiy Oncological Dispensary in 2000-2009 yrs there was conducted combined treatment of 60 patients, suffering metastatic CRR. Combined treatment consisted of the large bowel tumor extirpation, hepatic resection and adjuvant chemotherapy (ACT). Median of overall survival in patients after combined treatment conduction had constituted 24.1 mo. The trustworthy improvement of late follow-up results was stimulated by combined application of hepatic resection with ACT. Small rate of complications and low postoperative lethality were noted.

[Stages of breast cancer].

A comparative analysis of several systems of the assessment of the degree of spreading of malignant process is presented in the article. Stage principles of malignant neoplasms, which are used by the National Cancer Register do not respond current requirements as these principles do not single out preinvasive carcinoma and even more patients with I and II stages malignant neoplasms are brought into one group. Last reduction of the International TNM breast cancer classification (2002, TNM-6) reflects further progress in understanding biology of this localization and possibilities of the diagnostics. This classification differs considerably from previous reductions (TNM-4 and TNM-5) and especially Soviet classification dated 1985. The study carried out by the authors showed importance of differential approach to the assessment of regional lymphatic nodes lesion on depending their quantity (in diapason from 1 to 3; 4-9; 10 and more). The authors stated in the article that there is a certain discrepancy of some clinical and pathohistological parameters (N not equal to pN) in the last reduction of TNM classification of breast cancer and interpretation of some categories of the system is over-complex.

[The use of enterosorption and plasmapheresis during the chemotherapy of lung cancer patients]. / Zastosuvannia enterosorbtsiï ta plazmaferezu v protsesi khimioterapiï khvorykh na rak leheniv.

As many as 44 patients with stage IIIB and IV carcinoma of the lung (n = 27 and 17 respectively) were studied for clinical and laboratory manifestations of endogenous intoxication syndrome during the administration of CAPF chemotherapy treatments. The use for detoxicating purposes of siliceous enterosorbents and plasmapheresis both alone and combined resulted in alleviation of gastrointestinal and hematological complications and permitted improving the quality of the patients' lives.