RESUMO
We investigated the feasibility of using 123I-iodoantipyrine (123I-IAP) and 99mTc-labeled macroaggregated albumin (99mTc-MAA) to describe and compare the distributions of perfusion and water content in lung injuries. These radiopharmaceuticals were administered to 9 rabbits, 5 control and 4 with lung injuries. Isolated lungs were imaged by a scintillation gamma camera. The distribution of 123I-IAP outlined the entire lung mass whereas perfusion defect in the distribution of 99mTc-MAA was seen clearly in the case of severe lung injury.
Assuntos
Água Extravascular Pulmonar/metabolismo , Circulação Pulmonar , Edema Pulmonar/diagnóstico por imagem , Animais , Antipirina/análogos & derivados , Feminino , Técnicas In Vitro , Radioisótopos do Iodo , Coelhos , Cintilografia , Agregado de Albumina Marcado com Tecnécio Tc 99mRESUMO
The effect of ingesting cellulose, pectin, and psyllium with orally administered lactose in water or milk was tested in six lactose malabsorbers. Breath hydrogen tests were used to evaluate lactose malabsorption and mouth-to-cecum transit times. Addition of psyllium significantly reduced the breath hydrogen response, and symptoms in each subject; whereas, less diminution of expired hydrogen was seen after cellulose or pectin was added. The effect of each fiber on gastric emptying rates of an equal volume liquid meal was evaluated in three volunteers. Pectin had no effect, while the cellulose and psyllium modestly delayed emptying at approximately 30 min.