Postoperative Analgesic Effect of Bilateral Quadratus Lumborum Block (QLB) for Canine Laparoscopic Ovariectomy: Comparison of Two Concentrations of Ropivacaine.

The aim of this study was to evaluate the effect of the transverse quadratus lumborum block (QLBLQL-T) on time to the first postoperative rescue analgesia in dogs submitted to laparoscopic ovariectomy. A total of twenty-three female dogs were included. Dogs were randomly assigned to receive a bilateral QLBLQL-T, performed either with 0.3 mL kg-1 ropivacaine 0.5% [group QLB0.5% (n = 8)] or with ropivacaine 0.33% [group QLB0.33% (n = 8)] or a fentanyl-based protocol [group No-QLB (n = 7)]. Dogs were premedicated intravenously (IV) with fentanyl 5 mcg kg-1, general anesthesia was induced IV with propofol and maintained with sevoflurane. Invasive mean arterial pressure (MAP) values were recorded five minutes before and five minutes after performing the QLBLQL-T. The short-form of the Glasgow composite measure pain scale was used every hour after extubation, and methadone 0.2 mg kg-1 was administered IV when pain score was ≥5/24. Kolmogorov-Smirnov test, ANOVA test combined with Tukey post hoc test, Student's T-test and Chi-square test were used to analyze data; p < 0.05. Time from QLBLQL-T to the first rescue analgesia was significantly longer in QLB0.5% than in group QLB0.33% and No-QLB. MAP pre- and post-block decreased significantly only in group QLB0.33%.

Saphenous and Sciatic Nerve Blockade with and without Obturator Nerve Block for Tibial Plateau Levelling Osteotomy Surgery in Dogs: A Randomized Controlled Trial.

The objective of our study was to compare the efficacy of sciatic and saphenous ultrasound nerve blocks with and without US-guided obturator nerve block in dogs undergoing tibial-plateau-levelling-osteotomy (TPLO) surgery. This study was developed in two phases: identification of an ultrasound window in the inguinal region for obturator nerve block and utilization of it in dogs undergoing TPLO. Dogs were assigned randomly to one of two groups: one received the three blocks with 0.5% ropivacaine (ON group) and the second one (NoON group) with NaCl instead of ropivacaine for the obturator block. In phase 1, the obturator nerve was visible between the pectineus and the abductor muscles and was approached using an in-plane technique. It was possible to use the ultrasound window for phase two. The number of dogs that received at least one bolus of intraoperative rescue analgesia in the NoON group (12/15 dogs) was significantly higher (p = 0.003) in comparison with the ON group (4/15). An ultrasound window to block the obturator nerve in the inguinal compartment with an in-plane technique was found. The use of this approach could produce adequate analgesia with less motor function impairment in dogs for TPLO surgery.

Through the Newsfeed Glass: Rethinking Filter Bubbles and Echo Chambers.

In this paper, we will re-elaborate the notions of filter bubble and of echo chamber by considering human cognitive systems' limitations in everyday interactions and how they experience digital technologies. Researchers who applied the concept of filter bubble and echo chambers in empirical investigations see them as forms of algorithmically-caused systems that seclude the users of digital technologies from viewpoints and opinions that oppose theirs. However, a significant majority of empirical research has shown that users do find and interact with opposing views. Furthermore, we argue that the notion of filter bubble overestimates the social impact of digital technologies in explaining social and political developments without considering the not-only-technological circumstances of online behavior and interaction. This provides us with motivation to reconsider this notion's validity and re-elaborate it in light of existing epistemological theories that deal with the discomfort people experience when dealing with what they do not know. Therefore, we will survey a series of philosophical reflections regarding the epistemic limitations of human cognitive systems. In particular, we will discuss how knowledge and mere belief are phenomenologically indistinguishable and how people's experience of having their beliefs challenged is cause of epistemic discomfort. We will then go on to argue, in contrast with Pariser's assumptions, that digital media users might tend to conform to their held viewpoints because of the "immediate" way they experience opposing viewpoints. Since online people experience others and their viewpoints as material features of digital environments, we maintain that this modality of confronting oneself with contrasting opinions prompts users to reinforce their preexisting beliefs and attitudes.