RESUMO
For 12 years, recombination rate was assessed in Drosophila melanogaster males exposed on a thermoelectric power station (TPS) of Moscow. In 1994, experiments were also carried out on another Moscow TPS for comparison. The recombination frequency in exposed males was two- or threefold higher than in the control sample. Recombination frequencies observed in different years did not significantly differ from each other. Likewise, no significant difference was observed for the results obtained on two TPSs. A dramatic increase in recombination frequency in flies exposed on TPS was considered as an adequate response to high concentrations of effective mutagens discharged by TPS.
Assuntos
Drosophila melanogaster/genética , Animais , Masculino , Moscou , Recombinação GenéticaRESUMO
We studied recombination in Drosophila melanogaster males exposed in a thermoelectric power station in Moscow for six years and, for comparison, in another thermoelectric power station during 1994. The frequency of recombination in the experimental males was two to three times that in the control. The annual differences in the frequency of recombination in the experimental males were not statistically significant. The differences between the data obtained for two different thermoelectric power stations were not statistically significant as well. A marked increase in the frequency of recombination in the D. melanogaster males exposed at thermoelectric power stations may be considered as an adequate reaction to the presence of a sufficient amount of effective mutagens in discharges of thermoelectric power stations.
Assuntos
Poluentes Atmosféricos/efeitos adversos , Mutagênese/efeitos dos fármacos , Recombinação Genética/efeitos dos fármacos , Animais , Cromossomos/genética , Drosophila melanogaster , Masculino , Moscou , Mutagênese/genética , Centrais Elétricas , Recombinação Genética/genética , Fatores de TempoAssuntos
Enzimas/genética , Genes Dominantes , Genes Letais , Heterozigoto , Voo Espacial , Animais , Drosophila melanogaster , Frequência do GeneRESUMO
For four years, genetic recombination was studied in Drosophila melanogaster males kept at a thermoelectric power station (TPS) in Moscow; a TPS located in another city district was taken for comparison in 1994. It was found that, in the experimental males, recombination frequency was two- to threefold higher than in the control flies. Temporal variations in recombination frequency during four years were not statistically significant. The data obtained at the two TPSs also did not significantly differ from each other. The considerable increase of the recombination frequency in Drosophila kept at the TPS may be considered an appropriate response to exposure to effective mutagens that were abundant in the TPS discharges.
Assuntos
Drosophila melanogaster/genética , Campos Eletromagnéticos , Monitoramento Ambiental/métodos , Recombinação Genética , Animais , Masculino , Moscou , Mutagênicos/toxicidade , Federação RussaAssuntos
Drosophila melanogaster/genética , Recombinação Genética , Voo Espacial , Ausência de Peso , Animais , Masculino , MutaçãoRESUMO
An experiment with Drosophila melanogaster males was performed aboard the Artificial Satellite "Kosmos-1667". Mutagenic effects of a 7-day space flight on intergene recombination in chromosome 2 were studied. The space flight factors decreased the frequency of recombination. A model experiment on a laboratory centrifuge demonstrated insignificant increase in recombination frequency caused by acceleration.
Assuntos
Drosophila melanogaster/genética , Recombinação Genética , Voo Espacial , AnimaisAssuntos
Troca Genética , Drosophila melanogaster/genética , Voo Espacial , Animais , Gravitação , MasculinoRESUMO
Effects of space flight factors on chromosomal nondisjunctions, breaks and mitotic recombination in Drosophila melanogaster males were studied. It was shown that space flight conditions increased the frequencies of nondisjunctions, breaks and mitotic recombination in chromosomes. It was established that the vibration and acceleration effects could not serve to explain the data obtained. On the basis of these data, it may be suggested that weightlessness and cosmic radiation are the main factors which are responsible for the effects observed.
Assuntos
Aberrações Cromossômicas , Drosophila melanogaster/genética , Não Disjunção Genética , Recombinação Genética , Voo Espacial , Animais , Cruzamentos Genéticos , MasculinoRESUMO
Two experiments with Drosophila melanogaster males were performed aboard the Salyut 6 orbital station. Mutagenic effects of a 8 day space flight on sex chromosome nondisjunction and intergene recombination in chromosome II were studied. The space flight factors (SFF) increased the frequency of chromosome nondisjunction and recombination. The model experiments showed that the combined effects of vibration and acceleration do not cover the whole spectrum of space flight mutagenic factors. These data suggest that heavy space ions are mainly responsible for the observed effect.
