[Optimization of eccentric rotation gamma-irradiation of the ribs]. / Optimizatsiia ékstsentricheskogo rotatsionnogo gamma-oblucheniia reber.

The authors developed a method of eccentric rotation therapy of the ribs by the Aspekt-I optimization program using for irradiation the Altai-MT gamma-apparatus with an automated control system. A mean fractionation regimen (5 fractions of 4 Gy daily) was used. An analgesic effect for 5-10 days was observed in all patients, a complete effect--1-1.5 mos. after treatment.

[Use of shielding blocks for field formation in gamma teletherapy]. / Ispol'zovanie zashchitnykh blokov dlia formirovaniia polei pri distantsionnoi gamma-terapii.

Based on experimentally obtained dose distributions for irregular fields formed on the Rokus-M apparatus by means of shield blocks, a formula for the manual calculation of a dose rate in the open part of an irregular field was proposed. The formula makes use of the tissue air ratio and takes into account change of an equivalent field area in case of the use of central, shifted and edge blocks or their combinations.

[Method of gamma teletherapy in prostatic cancer]. / Metodika distantsionnoi gamma-terapii raka predstatel'noi zhelezy.

Three variants of gamma-beam therapy of prostatic cancer were worked out on the basis of a thorough topometric preparation, an analysis of dose distributions using computer, and taking account of tumor dissemination. It has been shown that moving one- or two-field gamma-beam therapy is indicated in cases when tumor lies within the limits of the prostate only. When it affects regional lymph nodes the combination of moving gamma-beam therapy with static 4-field cross irradiation with the ratio of doses from the front and back fields 2:1 is recommended. When tumor involves the nearest lymphatic collectors gamma-beam therapy is supplemented by estrogens with stage-by-stage irradiation of primary tumor, regional lymph nodes (by the above schemes) and the paraaortal group of lymph nodes from 2 opposite shaped fields, a focal dose to these nodes being 30-40 Gy only. The summary focal dose to the regional lymph nodes is 45-50 Gy, to primary tumor 65-70 Gy. The above variants of gamma-beam therapy were used for the treatment of 69 patients with prostatic cancer, Stages II-IV. Not a single patient developed marked reactions and late complications 6-36 mos. after therapy, 61% of the patients lived over 3 yrs.