RESUMO
The effects of platinum nanoparticles on the morphological structures of the solid phase of blood serum and the tone of cerebral microvessels as indicators of the dynamics of homeostasis were studied on outbred albino male rats (n=40) weighing 300-350 g. Platinum nanoparticles were injected to experimental animals in 1 ml of physiological saline. For systemic BP measurements and blood sampling, the femoral artery was isolated and catheterized. The study of solid phase structures of blood serum was conducted by the method of cuneiform dehydration. The results showed that injection of platinum nanoparticles significantly affected the body of experimental animals.
Assuntos
Encéfalo/diagnóstico por imagem , Artérias Cerebrais/diagnóstico por imagem , Meios de Contraste/química , Fluxometria por Laser-Doppler/métodos , Nanopartículas Metálicas/química , Platina/química , Animais , Animais não Endogâmicos , Velocidade do Fluxo Sanguíneo/fisiologia , Circulação Cerebrovascular/fisiologia , Meios de Contraste/administração & dosagem , Masculino , Nanopartículas Metálicas/administração & dosagem , Platina/administração & dosagem , RatosRESUMO
The authors analyze their personal observations of 76 patients with limited pyo-destructive diseases of the kidneys and perirenal space and describe the results of a minimally invasive method of treatment of this category of patients. Positive results were noted in 94% of the patients. The absence of complications, low lethality (1.5%), technical simplicity allow this method to be considered as the most adequate to modern requirements.
