[Lung cancer according to autopsy data from the Pathologicoanatomical Institute in Hradec Králové (Czechoslovak SSR) for 1978]. / Rak legkikh po sektsionnomu materialu patologoanatomicheskogo instituta v Gradtse Kralove (ChSSR) za 1978 g.

The analysis of autopsy materials for the year revealed 75 cases of pulmonary carcinoma, predominantly in men (10.9:1). Particular attention was paid to the association of pulmonary carcinoma with the duration and intensity of cigarette smoking by the patients. The results of the comparison of these data suggest that the majority of men (94.1%) dying of pulmonary carcinoma had been inveterate smokers who had smoked on an average 388,000 cigarettes during their lifetime. A high per cent of pulmonary carcinoma among other fatal diseases and a significant number of cases of this disease unrecognized before death were noted.

[Pancreatic lesion in newborn mice caused by Coxsackie B1 virus]. / Povrezhdenie podzheludochnoi zhelezy novorozhdennykh myshei, vyzvannoe virusom Koksaki B1.

Changes in the pancreatic gland manifested by necrosis of excretory cells and marked atrophy of insulae with the loss of beta-cells producing insulin were observed experimentally in suckling mice infected with Coxsackie B1 virus. It is suggested that the above changes of the pancreas may be a model of human diseases caused by Coxsackie viruses, including a model of development of some cases of diabetes.

[The stratified tuberculoma caused by Mycobacterium kansasii with cavitation (author's transl)]. / Das durch Mycobacterium kansasii hervorgerufene, geschichtete Tuberkulom mit Zerfallshöhle.

Report on a 39 years old female textile worker with an acute cavity. M. kansasii was repeatedly isolated by cultivation from the sputum. The patient became negative by treatment with INH, SM, PAS, Ethionamide, but the cavity persisted. Therefore seven months after the onset of the disease the left upper lobe was resected. A colliquative Stratified tuberculoma and some lesions of caseated bronchitis and peribronchitis were found in the neigh bourhood. Clusters and microcolonies of M. kansasii could be observed as well in the wall of the cavity as in the centre of caseated bronchial lesions. The mycobacteria had a characteristic shabe of long segmentated rods. All about the microcolonies situated in the lumina of small bronchi and bronchioli caseated lesions were present, surrounded by specific granular tissue consisting of epithelial cells, some Langhans giant cells, lymphocytes and fibrocytes. The alterations caused by M. kansasii did not differ from those lesions caused by M. tuberculosis (human.) formerly described as stratified tuberculoma and caseated bronchial lesions with mycobacteria centrally located.