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Clin Toxicol (Phila) ; 46(3): 250-3, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17852157

RESUMO

BACKGROUND: Phenol (carbolic acid, a higher alcohol) has been used for local analgesic therapy for a long time. Several complications of phenol therapy can occur by exposure through inhalational, oral, and dermal routes. Renal and pulmonary toxicity arising from the exposure to injectable phenol, however, has only been reported in a few case reports. CASE PRESENTATION: A 50-year-old man inadvertently received 10 cc of 89% phenol injection. It resulted in the development of acute respiratory and renal failure requiring intubation and hemodialysis, respectively. He improved clinically with the recovery of renal function. However, the chest x-ray and CT scan showed persistent nodular pulmonary infiltrates which resolved by six months. CONCLUSION: We report here an unusual case of acute respiratory and acute renal failure following accidental overdose of phenol. The case highlights potential development of multiple organ failure with persistence of organ dysfunction, an unusual danger associated with the overdose of injectable phenol for neurolysis.


Assuntos
Analgésicos/intoxicação , Dor/complicações , Fenóis/intoxicação , Doença Aguda , Injúria Renal Aguda/induzido quimicamente , Injúria Renal Aguda/fisiopatologia , Adulto , Analgésicos/uso terapêutico , Overdose de Drogas , Serviços Médicos de Emergência , Humanos , Testes de Função Renal , Pulmão/diagnóstico por imagem , Masculino , Dor/tratamento farmacológico , Fenóis/uso terapêutico , Diálise Renal , Insuficiência Respiratória/induzido quimicamente , Insuficiência Respiratória/fisiopatologia , Tomografia Computadorizada por Raios X
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