A long-term follow-up of allergic diseases in Iceland.

INTRODUCTION: Allergic disorders are an increasing health problem in many countries, in particular among children. We have evaluated the prevalence and manifestations of allergy in a cohort of young Icelanders for more than two decades. Variations in the epidemiology and clinical expression of allergy in different communities may help to identify etiological factors contributing to these disorders. METHODS: A cohort of 179 children has been monitored for allergic manifestations for two decades, at the ages of two, four, eight, and 15 years, and most recently at the age of 21 years involving 120 of the participants. RESULTS: Cumulative prevalences of 40%, 45%, and 29% have been observed, respectively, for rhinoconjunctivitis, eczema, and asthma during the study period. None had developed rhinoconjunctivitis at the age of about 2 years, but the point prevalence gradually increased to 33% at the age of 21 years. Conversely, the prevalence of eczema was 31% at the age of 2 years, but gradually declined to 8% at the age of 21 years. The prevalence of asthma peaked at 28% at the age of 4 years, but declined thereafter and has remained stable at about 13% from the age of eight to 21 years. DISCUSSION: The prevalence of allergic diseases is high in Iceland among children and young individuals. Asthma and atopic eczema are very common in childhood, but decreases with age while the prevalence of rhinoconjunctivitis increases markedly. The very high and increasing prevalence of rhinoconjunctivitis among 15- to 21-year-old individuals is noteworthy.

An increasing incidence of mastoiditis in children in Iceland.

The incidence of mastoiditis, a known complication of otitis media, may reflect the incidence and treatment of otitis media. The aim of the study was to evaluate the incidence of mastoiditis in Iceland, especially in children, and the possible correlation with antibiotic usage. Patients with mastoiditis during 1984-2002 were identified and information on antibiotic usage in children in the y 1989-2002 was obtained. 84 patients were diagnosed with mastoiditis during 1984-2002, 52 (62%) of whom were less than 18 y of age. 26 (50%) children were less than 3 y of age. During the y 1999-2002, 28 children were diagnosed with mastoiditis, of whom 15 (54%) were diagnosed with otitis media within a week prior to admission. 11 (73%) were treated with antibiotics and 4 (27%) were not. During 1989-2002 a correlation was detected between decreased antibiotic usage in children and increased incidence of mastoiditis (r=-0.68; p=0.007). Following changes in guidelines for antibiotic prescriptions for otitis media in Iceland during the 1990s, antibiotic usage decreased but the incidence of mastoiditis increased. It is uncertain if this is a causal relationship. It is important to treat otitis media correctly while being alert for complications, especially in young children.

[Mastoiditis in children in Iceland]. / Stikilbólga hjá börnum á Islandi.

INTRODUCTION: Mastoiditis is an infection in the mastoid process and is a complication of otitis media. Studies have revealed that the incidence might be increasing with altered antibiotic usage. The aim of the current study was to describe the epidemiology, clinical symptoms and treatment of mastoiditis in Iceland during the last two decades with special emphasis on children and to study possible correlations between antibiotic use and incidence of mastoiditis. PATIENTS AND METHODS: Information on patients diagnosed with mastoiditis during the period 1984-2002 at The Children's Hospital Iceland, The Department of Paediatrics, Landakoti and Landspitali--University Hospital Iceland was gathered and clinical data were recorded from patients records of children diagnosed with mastoiditis during 1999-2002. Information on antibiotic use during the years 1989-2002 was obtained from the Ministry of Health in Iceland. RESULTS: Eighty-four patients were diagnosed with mastoiditis during the period 1984-2002. Of those, 52 (62%) were children less than 18 years of age. The mean age of those children was 2 years and 8 months. Boys were 58%. Twenty six (50%) of the children were less than three years old. During the years 1999-2002, a total of 28 children were diagnosed; the mean age was 2 years and 2 months. Fifteen children (54%) sought medical attention within a week prior to admission to hospital and had been diagnosed with otitis media. Eleven children (73%) were appropriately treated with antibiotics prior to the diagnosis of mastoiditis but four (27%) received no antibiotics. During the period 1989-2002, a statistically significant correlation was detected between decreased antibiotic use among children and increasing incidence of mastoiditis (r=-0.68; p=0.007). DISCUSSION: Following changes in guidelines for antibiotic prescriptions for otitis media in Iceland during the nineties, antibiotic use in children decreased at the same time as the incidence for mastoiditis increased. It is uncertain, however, if a causal relationship exists. It is important to diagnose and appropriately treat otitis media, while staying alert for serious complications, especially in young children.