RESUMO
Antimicrobial resistance is a widespread global health problem. The presence of resistant bacteria and antibiotic resistance genes has been demonstrated not only in humans but also in animals, including pets. Stray cats share the urban environment with people and pets. This may facilitate transmission of resistant bacteria and resistance genes between stray animals, people and domestic animals. Several studies have investigated the role of stray cats as a fecal carrier of ESBL-producing bacteria. However, there are many genes and resistance mechanisms that can be detected in commensal E. coli, which, because of its genetic plasticity, is considered an indicator for monitoring antibiotic resistance. In this study, rectal swabs were collected from stray cats from colonies and shelters in the city of Monza (Monza Brianza, Italy) to isolate commensal E. coli. Phenotypic tests, such as the minimum inhibitory concentration (MIC) and the double disc test (DDST), and molecular analyses to detect antimicrobial resistance genes (ARGs) were used to study the resistance of these isolates. The results obtained confirm that stray cats can carry ESBL-producing E. coli (6.7%) and genes conferring resistance to other important antibiotic classes such as tetracyclines and sulfonamides.
RESUMO
Introducción El cáncer de mama es el más frecuente en mujeres, aunque es de baja incidencia en pacientes jóvenes. Objetivos Analizar retrospectivamente las biopsias realizadas en pacientes menores de 35 años, en el Grupo Médico Rostagno en el período comprendido entre enero de 2010 y enero de 2015, clasificarlas según edad, presentación clínica e imagenológica y realizar una correlación anátomo-radiológica. Material y método Se estudiaron 381 biopsias realizadas a pacientes de hasta 35 años en el período comprendido entre enero de 2010 y enero de 2015. Resultados La mayoría de las biopsias 247(66%) se realizaron en pacientes mayores de 30 años. Únicamente 28 (8%) fueron clínicamente palpables. Sobre el total, 328 (89%) correspondieron a lesiones nodulares diagnosticadas por ecografía, según categoría bi-rads; 187 (50%) se clasificaron bi-rads 4. Por otra parte, 301 (81%) fueron core biopsia bajo guía ecográfica. Únicamente 20 (5%) fueron malignas, y el carcinoma más frecuente fue el Carcinoma Ductal Infiltrante (55%). Conclusiones Las pacientes jóvenes presentan, en su mayoría, lesiones nodulares, con una baja incidencia de lesiones malignas. La lesión maligna más frecuente fue el Carcinoma Ductal Infiltrante tipo nos de alto grado histológico
Introduction Breast cancer is the most frequent in women, although it is of low incidence in young patients. Objectives To analyze retrospectively biopsies performed in patients under 35 years of age, classify them according to age, clinical and imaging presentation and perform an anatomo-radiological correlation. Materials and method We studied 381 biopsies performed on patients up to 35 years of age in the period between January 2010 and January 2015. Results The majority of biopsies 247 (66%) were performed in patients older than 30 years, only 28 (8%) were clinically palpable. 328 (89%) corresponded to nodular lesions, diagnosed by ultrasound, according to bi-rads category 187 (50%) were classified bi-rads 4. 301 (81%) were Core biopsy under ultrasound guidance. Only 20 (5%) were malignant, and the most frequent carcinoma was Infiltrating Ductal Carcinoma (55%). Conclusions Young patients have mostly nodular lesions, with a low incidence of malignant lesions. The most frequent malignant lesion was nos type Infiltrating Ductal Carcinoma of high histological grade
