The Comparison of Age-related Change in Retinal Nerve Fiber Layer and Ganglion Cell Complex Thicknesses between Glaucoma Suspects and Healthy Individuals.

Aim: The purpose of this study is to investigate the difference of change in the retinal nerve fiber layer (RNFL) and the ganglion cell complex (GCC) thickness according to age in glaucoma suspect individuals and healthy subjects. Materials and methods: Thicknesses of RNFL and GCC were measured with spectral domain optical coherence tomography (SD-OCT) in glaucoma-suspected individuals and healthy subjects. The differences in age, overall mean, four quadrants, and 12 clock-hour sectors of RNFL and overall mean, superior half, and inferior half GCC thicknesses between glaucoma suspects and healthy participants were analyzed and compared using linear regression analyses. Results: There were 201 glaucoma-suspect individuals and 121 healthy subjects with a mean age of 38.89 and 40.26 years, respectively (p = 0.27). The mean overall RNFL thickness was found to be 97.76 and 97.43 µm in healthy individuals and glaucoma suspects (p = 0.72). The mean overall GCC thickness was found to be 111.30 and 104.67 µm in healthy individuals and glaucoma suspects, respectively (p < 0.001). There was a 0.11 µm decrease per year found in overall GCC thickness in glaucoma suspects and 0.23 µm decreases per year in overall GCC thickness in healthy individuals (p < 0.001). There was a 0.02 µm decrease per year found in overall RNFL thickness in glaucoma suspects and a 0.29 µm decrease per year in overall RNFL thickness in healthy individuals (p < 0.001). However, these per-year decreases in GCC thickness glaucoma suspects and healthy individuals were not found to be statistically significant (p = 0.21); on the other hand, this difference for RNFL thickness was significant (p < 0.001). Conclusion: It was found that the thicknesses of RNFL and GCC were different between glaucoma suspects and healthy individuals. However, age-related decay in the RNFL and GCC thicknesses was not uniform in healthy individuals and glaucoma suspects. Clinical significance: It was found that the RNFL thickness and GCC thickness were lower in glaucoma suspects than in healthy controls eyes. However, an age-related decrease of RNFL and GCC thicknesses were found to be less in glaucoma suspects compared with healthy controls. How to cite this article: Firatli G, Elibol A, Altinbas E, et al. The Comparison of Age-related Change in Retinal Nerve Fiber Layer and Ganglion Cell Complex Thicknesses between Glaucoma Suspects and Healthy Individuals. J Curr Glaucoma Pract 2023;17(1):22-29.

Assessment of risk factors on eye dryness in young adults using visual display device in both contact lens wearers and non-wearers.

PURPOSE: Researchers are interested in examining the impact of visual display devices (VDDs) on the development of dry eye illness because their use is becoming more common among college students. The goal of this study was to see if there was a link between certain risk factors and the development of eye dryness in VDDs using young adults who wore contact lenses and those who did not. METHODS: The self-administrated survey was hosted in Google Forms, sent via e-mail to the participants. It consisted of two parts of assessing different risk factors (i.e., environmental conditions, angle of gaze, and years of VDD use) with contact lens use and Ocular Surface Disease Index (OSDI) questionnaire. The OSDI scores of the entire sample who suffer from dry eye and the subgroup using contact lenses were calculated. The relationship between different risk factors with the OSDI scores was also assessed. RESULTS: A total of 274 young adults from college students and academic staff (216 female, 58 male) were suffering from eye dryness. Eighty-eight of the 274 participants wore contact lenses. The mean OSDI scores of the 274 young adults were 32.92. Mean OSDI scores in contact lens wearers and non-wearers were 34.36 and 32.24, respectively (p < 0.01). There was a statistically significant relationship between OSDI score and indoor environmental conditions in computer using VDD group. Using a computer in a dark environment and above the line of sight resulted in a higher OSDI scores. Females who wore contact lenses while using a computer for more than three years had significantly higher OSDI scores than non-wearer females. Tablet type VDD use increased the mean ODSI scores of the contact lens wearers significantly. CONCLUSIONS: Dry eye symptoms were shown to be increased in the contact lens wearer group with the increased duration of computer VDD use, decreased indoor environmental brightness conditions, and above the line of sight.

Clinical outcomes of single-bundle versus double-bundle ACL reconstruction in adolescent elite athletes: A retrospective comparative study.

OBJECTIVE: The aim of the study was to evaluate the single bundle (SB) and double bundle (DB) anterior cruciate ligament (ACL) reconstruction in terms of graft survival, complications, and patient reported functional outcomes in adolescent athletes. METHODS: In this retrospective study, 89 elite adolescent athletes who underwent either SB or DB ACL reconstruction were included. All patients were then divided into two groups: group 1 including 51 patients with SB ACL reconstruction (31 male, 20 female; mean age = 15.4 ± 1.03 years) and group 2 including 38 patients with DB ACL (30 male, 8 female; mean age = 15.7 ± 1.3 years). Clinical data were obtained, comprising skeletal maturity, sports type, ACL reconstruction technique, Lachman scores, KT-1000™ arthrometer measurement, additional meniscal procedures as well as International Knee Documentation Committee (IKDC) score, Cincinnati score, and graft size. RESULTS: The mean follow-up period was 53.1 ± 8.6 months in group 1 and 46.4± 9.1 months in group 2 (P = 0.61). The type of ACL reconstruction technique (SB or DB), gender, skeletal maturity, sports type, additional meniscal procedures and Lachman scores were not associated with the re-rupture of the ACL (P > 0.05). Moreover, ACL reconstruction technique did not effect the rate of re-rupture of an ACL. There were 21 re-ruptures (23.5%) and 11 (12.3%) contralateral ACL ruptures in total. Among 21 reruptures, 12 of them were in the DB group while nine of them in the SB group (P > 0.05). The groups did not differ with respect to age, the injured side, the time from injury to surgery, the postoperative follow-up time, or the preoperative physical examination results KT-1000 device (SSD), Cincinnati score, IKDC objective and subjective score,Lachman test and pivot-shift test). CONCLUSION: There are no differences in the re-rupture of an ACL, patient reported outcomes, and complications in adolescent elite players, when either an SB or DB technique is performed. LEVEL OF EVIDENCE: Level III, Therapeuthic Study.

Partial Rotator Cuff Repair With Superior Capsular Reconstruction Using the Biceps Tendon Is as Effective as Superior Capsular Reconstruction Using a Tensor Fasciae Latae Autograft in the Treatment of Irreparable Massive Rotator Cuff Tears.

BACKGROUND: Several treatment options are available for stable massive rotator cuff tears, including partial repair with or without tissue augmentation, tendon transfer, superior capsular reconstruction (SCR), and reverse shoulder arthroplasty. PURPOSE/HYPOTHESIS: The purpose of this study was to compare the outcomes and effectiveness of partial rotator cuff repair with SCR using the long head of the biceps tendon (PRCR-SCRB) and SCR with a tensor fasciae latae autograft (SCRTF) for the treatment of rotator cuff tears with severe fatty degeneration. The hypothesis of this study was that SCRTF would be superior to PRCR-SCRB in functional and anatomic outcomes. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: A total of 26 consecutive patients with massive and fatty degenerative rotator cuff tears were treated surgically. Patients were divided into either the PRCR-SCRB group (n = 14) or SCRTF group (n = 12). Functional outcomes were assessed at final follow-up, and the acromiohumeral distance (AHD) was measured. RESULTS: All functional scores significantly improved in both groups at final follow-up. The PRCR-SCRB group showed better overall outcomes in terms of the visual analog scale for pain; American Shoulder and Elbow Surgeons score; and Quick Disabilities of the Arm, Shoulder and Hand, but these differences were not statistically significant. Better outcomes were found for only the AHD for the PRCR-SCRB group without statistical significance (P = .4). No statistical difference was found in terms of retear rate. CONCLUSION: PRCR-SCRB had comparable outcomes and improvement in AHD compared with SCRTF without the need for additional graft harvesting.