RESUMO
A case of ulcerative proctitis complicating chrysotherapy for rheumatoid arthritis and a literature review of gold induced enterocolitis is presented. Only 26 patients have been reported with this complication. No specific therapy is available, except supportive measures and cessation of gold therapy.
Assuntos
Colite Ulcerativa/induzido quimicamente , Tiomalato Sódico de Ouro/efeitos adversos , Artrite Reumatoide/tratamento farmacológico , Colite Ulcerativa/patologia , Diarreia/induzido quimicamente , Tiomalato Sódico de Ouro/uso terapêutico , Humanos , Mucosa Intestinal/patologia , Masculino , Melena/induzido quimicamente , Pessoa de Meia-Idade , Proctite/induzido quimicamente , Reto/patologiaRESUMO
We report on a case of adriamycin cardiotoxicity occurring in a five-year-old boy treated for rhabdomyosarcoma. In addition to the usual features of myofibrillary degeneration associated with adriamycin, extreme endocardial fibrosis and mural thrombosis affecting the apical segments of both ventricles but particularly the left ventricle was seen at necropsy. The changes resembled classical endomyocardial fibrosis.
Assuntos
Cardiomiopatias/induzido quimicamente , Doxorrubicina/efeitos adversos , Fibrose Endomiocárdica/induzido quimicamente , Cardiomiopatias/patologia , Pré-Escolar , Fibrose Endomiocárdica/patologia , Ventrículos do Coração/patologia , Humanos , Masculino , Microscopia Eletrônica , Miocárdio/ultraestruturaRESUMO
When isolated from the female genital tract, diphtheroids are usually regarded as commensal organisms. Corynebacterium kutscheri however is a pathogen in laboratory rodents. We report a case in which C. kutscheri was isolated as a pure culture from the umbilical cord and from other surface sites in an infant. Histological examination of the cord and membranes demonstrated the organisms within these fetal tissues. The organisms evoked a fetal cellular response. The importance of recognising commensals as potential pathogens in states of altered host resistance in stressed.
