RESUMO
During the summer of 1992 renal failure was diagnosed in 232 grazing cattle in 85 herds on the west coast of Norway. The salient clinical signs were depression, anorexia and melaena or fresh blood in the faeces; diarrhoea was also commonly observed. The serum concentrations of creatinine, urea, magnesium and phosphorus, and the activities of glutamate dehydrogenase, aspartate aminotransferase and creatine kinase were above normal and the serum calcium concentration was below normal. Post mortem examinations consistently revealed renal tubular necrosis. In some cases there was liver necrosis and also erosions at the base of the tongue, in the oesophagus and in the jejunum and colon. The toxicity was probably caused by the plant Narthecium ossifragum (bog asphodel).
Assuntos
Doenças dos Bovinos/etiologia , Intoxicação por Plantas/veterinária , Plantas Tóxicas , Insuficiência Renal/veterinária , Animais , Bovinos , Doenças dos Bovinos/epidemiologia , Doenças dos Bovinos/patologia , Noruega/epidemiologia , Intoxicação por Plantas/complicações , Intoxicação por Plantas/epidemiologia , Intoxicação por Plantas/etiologia , Insuficiência Renal/complicações , Insuficiência Renal/epidemiologia , Insuficiência Renal/etiologiaRESUMO
The transmission of pathogenic bacteria from animals to humans is widely studied because of its public health importance. In this study, we show the transmission of Salmonella typhimurium from cattle which had received no growth-promoting antibiotics to humans who had direct contact with the ill animals. On one cattle farm, the veterinarian attending the sick animals became ill, and two other individuals living on the farm later developed salmonellosis. The strains isolated from both humans and animals at one farm were identical as to antibiotic susceptibility and phage type, and they were specifically traced by the presence of a common 24-megadalton plasmid. Restriction enzyme digests of this plasmid from both human and animal strains were identical. At another farm, tetracycline-resistant S. typhimurium strains possessing a different profile (eight plasmids) were isolated from both animals and humans. The tetracycline-resistant clone was also isolated from animals at a third farm, but with animals and humans having no known contact with those of the other two farms.
Assuntos
Plasmídeos , Salmonelose Animal/transmissão , Infecções por Salmonella/transmissão , Salmonella typhimurium/genética , Animais , Tipagem de Bacteriófagos , Bovinos , Doenças dos Bovinos/microbiologia , Clonagem Molecular , Conjugação Genética , DNA Bacteriano/análise , Resistência Microbiana a Medicamentos , Humanos , Noruega , Infecções por Salmonella/microbiologia , Salmonelose Animal/microbiologia , Salmonella typhimurium/classificação , Salmonella typhimurium/efeitos dos fármacos , Salmonella typhimurium/isolamento & purificação , Tetraciclina/farmacologiaRESUMO
Intravenous injections of disintegrated cells of Escherichia coli in chickens were almost constantly followed by extensive lesions in pulmonary arteries; the alterations consisted of mural fibrinoid necrosis, sometimes with slight intramural occurrence of mononuclear inflammatory cells and eosinophils. Massive perivascular accumulations of the same cell types were also very common findings. Affected arteries were frequently occluded by precipitates, predominantly consisting of the injected material, which were rapidly replaced by proliferating endothelial cells, resulting in obliterative lesions, where giant cells sometimes occurred. The conclusion was drawn that the arterial lesions could most adequately be categorized as hypersensitivity angiitis.
