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1.
Acta Radiol ; 64(6): 2126-2131, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-36991329

RESUMO

BACKGROUND: Projection radiography and, more recently, computed tomography (CT) play an important role in forensic age estimation. Both in terms of general criminal responsibility and government regulations concerning refugee care, it is important to differentiate correctly between youths and adults. A disadvantage of age estimation in CT is the ionizing radiation exposure. PURPOSE: To investigate how far the CT dose can be reduced without losing diagnostic confidence in assessing the different stages of ossification of the medial clavicle. MATERIAL AND METHODS: We prospectively scanned 25 postmortem cases with a fixed parameters protocol (FPP) and a care dose modulation protocol (CDMP) for different scan parameters. Two radiologists assessed the diagnostic image quality using a 5-point Likert scale. Inter-reader agreement was evaluated with Cohen's kappa. Differences in doses between FPP and CDMP were assessed with the one-tailed t-test. RESULTS: The best combination of diagnostic image quality and lowest radiation dose was obtained using a CDMP with 100 kV and 40 mAs and an FPP with 100 kV and 30 mAs. Doses for 120 kV were significantly higher (one-tailed P < 0.001). The diagnostic image quality for 80 kV was insufficient overall. DISCUSSION: Our results confirm that CT imaging at 100 kV allows a sufficient image quality that is diagnostic for age estimation in the ossification of the medial clavicle.


Assuntos
Clavícula , Redução da Medicação , Adulto , Adolescente , Humanos , Clavícula/diagnóstico por imagem , Estudos Prospectivos , Determinação da Idade pelo Esqueleto/métodos , Tomografia Computadorizada por Raios X/métodos , Epífises/diagnóstico por imagem , Doses de Radiação
2.
PLoS One ; 15(1): e0221544, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31986149

RESUMO

BACKGROUND: Computed tomography (CT) images of livers may show a hypo-attenuated structure alongside the falciform ligament, which can be a focal fatty pseudolesion and can mimic a malignancy. The preferred location is on the right parafissural site, ventral in segment IVa/b. The etiology is not clear, nor is it known how the histology of this location develops. These are evaluated in this study. METHODS: 40 adult cadavers with autopsy and / or postmortem CT in a university hospital and a forensic center were included. Liver biopsies were taken at the left side of the falciform ligament as control, and at the right side as the possible precursor of a pseudolesion; these were examined for collagen and fat content. Cadavers with steatotic (>5% fat) or fibrotic (>2% collagen) control samples were excluded. RESULTS: Significantly more collagen was present in the right parafissural liver parenchyma: median 0.68% (IQR: 0.32-1.17%), compared to the left side 0.48% (IQR: 0.21-0.75%) (p 0.008), with equal fat content and CT attenuation values. The etiophysiology goes back to the demise of the umbilical venes in the early embryonic and neonatal period. CONCLUSIONS: The right parafissural area contains more collagen and an equal amount of fat compared to the control left side. This supports the hypothesis of delayed, 'third' inflow: the postnatal change in blood supply from umbilical to portal leaves the downstream parafissural area hypoperfused leading to hypoxia which in turn results in collagen accumulation and the persistence of paraumbilical veins of Sappey.


Assuntos
Colágeno/metabolismo , Diagnóstico Diferencial , Fígado Gorduroso/diagnóstico , Neoplasias Hepáticas/diagnóstico , Fígado/diagnóstico por imagem , Adulto , Autopsia , Biópsia , Cadáver , Fígado Gorduroso/diagnóstico por imagem , Fígado Gorduroso/patologia , Feminino , Humanos , Ligamentos/diagnóstico por imagem , Ligamentos/patologia , Fígado/metabolismo , Fígado/patologia , Neoplasias Hepáticas/diagnóstico por imagem , Neoplasias Hepáticas/patologia , Masculino , Mesentério/diagnóstico por imagem , Mesentério/patologia , Pessoa de Meia-Idade , Veia Porta/diagnóstico por imagem , Veia Porta/patologia , Umbigo/diagnóstico por imagem , Umbigo/patologia
3.
Int J Legal Med ; 134(3): 1175-1183, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31602494

RESUMO

INTRODUCTION: Modern forensic investigations increasingly revert to 3D imaging techniques, such as computed tomography, magnetic resonance imaging, and 3D surface imaging. Findings are therefore often based on 3D data sets; however, this information is commonly reported and communicated within 2D imagery. The use of interactive 3D PDFs is already established in the scientific community but has yet to be implemented in the field of forensic medicine. METHODS AND MATERIALS: Three example cases were chosen to serve as exemplary data for the most commonly applied imaging techniques in postmortem imaging. 3D surface models were created from postmortem magnetic resonance imaging (PMMR), postmortem computed tomography (PMCT), and 3D surface imaging data sets. RESULTS: PMMR revealed a space-occupying subdural hemorrhage that led to ipsilateral compression of the brain tissue of the right hemisphere. PMCT displayed a defect in the skull on the left side of the temporal bone. 3D surface imaging data displayed a patterned discoloration on the inside of the left forearm. DISCUSSION: Interactive 3D PDFs offer the possibility to communicate 3D information to the reader while maintaining all the benefits of a regular 2D PDF. With Adobe Acrobat, the reader can interactively navigate through 3D data sets and create sufficient depth cues to generate a realistic 3D perception of the data. CONCLUSION: The interactive 3D PDF is a useful extension of standard 2D PDFs and has the potential to communicate 3D data to the reader in a more complete, more comprehensible, and less subjective manner than 2D PDFs.


Assuntos
Autopsia , Apresentação de Dados , Imageamento Tridimensional , Relatório de Pesquisa , Software , Documentação/métodos , Medicina Legal , Humanos
4.
BIS, Bol. Inst. Saúde (Impr.) ; 21(2): 50-66, dez. 2020.
Artigo em Português | Sec. Est. Saúde SP, CONASS, SESSP-ISPROD, Sec. Est. Saúde SP, SESSP-ISACERVO | ID: biblio-1361548

RESUMO

Este artigo tem como objetivo apresentar a história, trajetórias e movimentos do Coletivo Intercambiantes Brasil nos campos da Saúde Mental, álcool e outras drogas, sob a perspectiva contra hegemônica e emancipatória com as pessoas que habitam as ruas, valorizando as possibilidades dos encontros potentes e transformadores.


Assuntos
Psicotrópicos , Pessoas Mal Alojadas , Redução do Dano , Saúde Mental
5.
Forensic Sci Int ; 303: 109942, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31586908

RESUMO

BACKGROUND: Rib fractures are common and potentially life-threatening. Fast and correct detection as well as comprehensive visual overview of rib fractures are of clinical and forensic importance. This study compared two computed tomography (CT) reformation methods, curved planar reformation (CPR) with conventional multiplanar reformation (MPR), regarding detection of rib fractures in different readers. METHODS: Twelve postmortem CT datasets were retrospectively assessed for rib fractures using CPR and MPR. After defining the gold-standard regarding side, level, localization, and quantity of fractures, four reader groups per two readers consisting of radiologists, trauma surgeons, forensic pathologists, and laypersons, were evaluated for sensitivity, proportion of false positives, time to fracture detection, and subjective preference. RESULTS: Overall sensitivity for fracture detection did not vary significantly between both methods. However, it was significantly higher in trauma surgeons and laypersons when reading CPR compared to MPR (70.7% vs. 62.0%, p=0.038 and 33.7% vs. 22.1%, p=0.003 respectively). It was significantly lower in radiologists (63.8% vs. 76.8%, p=0.001). Forensic pathologists performed similarly with both methods (53.6% vs. 56.5%, p=0.549). All non-radiologists preferred the use of CPR (75%). All readers found CPR to provide better visual overview (100%). CONCLUSION: CPR may increase rib fracture detection rates of non-radiologists (i.e. trauma surgeons and laypersons) and provides a better visual overview. However, radiologists achieve higher fracture detection rates when allowed to work with the software tools they are more experienced with. The overall sensitivity was improvable and better visualization methods are warranted in order to avoid misdiagnosis and medicolegal errors regarding rib fracture detection.


Assuntos
Fraturas das Costelas/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Adulto , Idoso , Estudos Transversais , Reações Falso-Positivas , Feminino , Humanos , Imageamento Tridimensional , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Patologistas , Radiologistas , Cirurgiões , Adulto Jovem
6.
Eur Radiol ; 29(7): 3458-3466, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30796576

RESUMO

OBJECTIVE: The aims of this study were (1) to provide an overview of craniocervical magnetic resonance imaging (MR) findings following nonfatal strangulation (NFS), (2) to detect the time dependency of the presence of these findings, and (3) to explore the additional value of MR with regard to the forensic interpretation of NFS. METHODOLOGY: All 633 victims of manual strangulation between October 2011 and March 2018 were examined, including the case history and external findings. Following written consent, 114 cases were included in the study. The duration between the event, clinical forensic examination, and MR was noted. Radiologic images were reviewed by a clinical and a forensic radiologist. RESULTS: The case group consisted of 90 women and 24 men with a mean age of 32.5 years. Delimitable external findings were present in 93% (N = 106) of cases. MR yielded a positive finding in 43% of cases (N = 49). There was no significant difference in the mean time interval between examinations between MR-positive and MR-negative cases. Perilaryngeal fluid accumulation was associated with difficulty swallowing and victims put in a chokehold. All cerebral MR were unremarkable, except for one patient with edema of the corpus callosum. CONCLUSIONS: The role of craniocervical MR following NFS is currently limited, particularly with regard to the forensic interpretation of NFS. MR may reveal internal injury in victims who report subjective symptoms of airway compression and in those who were placed in a chokehold. The presence of MR findings is not dependent on immediate examinations following the assault. KEY POINTS: • Magnetic resonance imaging does not currently provide additional value for the estimation of the severity of nonfatal manual strangulation. • Magnetic resonance imaging of the neck may reveal internal injury in cases without external findings, particularly in victims placed in a chokehold and with symptoms of airway compression. • The incidence of carotid artery dissections and laryngeal fractures is low in victims of nonfatal manual strangulation.


Assuntos
Asfixia/diagnóstico , Vértebras Cervicais/patologia , Imageamento por Ressonância Magnética/métodos , Lesões do Pescoço/diagnóstico , Crânio/patologia , Adolescente , Adulto , Idoso , Asfixia/etiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Lesões do Pescoço/complicações , Adulto Jovem
7.
Br J Radiol ; 91(1084): 20170479, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29327945

RESUMO

OBJECTIVE: The purpose was to evaluate the presence of gas in the tissue adjacent to the laryngeal structures, "the gas bubble sign", in cases of hanging as a diagnostic indicator of neck trauma. METHODS: In this study, post-mortem CT (PMCT) scans and autopsies of 35 victims of hanging were examined to reveal age-dependent changes, laryngeal fracture, fracture location and the presence of gas. A matched group with cardiac arrest or intoxication was used as controls (n = 35). An autopsy was performed in each case. RESULTS: Incomplete suspension was the most common method in hanging. The thyroid horns (90.5%) were identified as the most vulnerable location for fractures. Laryngeal deformity and dislocation, which was only detected on PMCT, was observed in 57.1% and was concomitant with fractures in 83.3%. Laryngeal fractures are more common with advanced age (>40 years, 88.9%) and less common in younger subjects (<40 years, 29.4%). The gas bubble sign with regard to laryngeal fractures yielded a sensitivity of 79.2%, a positive predictive value of 95%, a specificity of 90.9%, a negative predictive value of 34.5% and an accuracy of 83%. CONCLUSION: The complex evaluation of the larynx is profoundly supported by PMCT and the detection of the gas bubble sign as a diagnostic indicator of neck trauma. This relevant diagnostic finding might aid in not only post-mortem cases but also clinical cases, for patients who survive an assault to the neck. Advances in knowledge: (1) The gas bubble sign is a diagnostic indicator of neck trauma in not putrefied bodies. (2) PMCT supports evaluation of trauma to the neck in hanging tremendously. (3) The diagnostic finding of gas located at the laryngeal structures may not only aid in post-mortem cases but also clinical cases of people who survive an assault to the neck.


Assuntos
Asfixia , Autopsia , Fraturas Ósseas/diagnóstico por imagem , Gases , Osso Hioide/diagnóstico por imagem , Osso Hioide/lesões , Laringe/diagnóstico por imagem , Laringe/lesões , Tomografia Computadorizada por Raios X , Adulto , Idoso , Causas de Morte , Feminino , Humanos , Imageamento Tridimensional , Masculino , Pessoa de Meia-Idade , Sensibilidade e Especificidade , Suicídio
8.
J Forensic Leg Med ; 54: 96-101, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29348074

RESUMO

Image registration software is frequently used in clinical radiology, e.g., for follow-up diagnosis. To a certain extent, the radiological identification of decedents (RadID) is comparable to a clinical follow-up diagnosis, in that two datasets from different dates are compared in terms of their anatomical characteristics (e.g., paranasal sinuses) or surgical implants. Due to the increasing use of computed tomography (CT) for head examinations in clinical radiology and the increased use of postmortem CT (PMCT) in forensic imaging, the comparison of three-dimensional (3D) clinical CT (termed as antemortem CT (AMCT) in this article) and PMCT datasets for RadID is becoming increasingly practical. In particular, the comparison of paranasal sinuses in AMCT and PMCT imaging is considered a suitable and reliable modality for RadID. However, previous publications regarding RadID based on comparisons of 3D datasets have not considered the implementation of image registration to provide software-side support for RadID. This article demonstrates and evaluates the use of a standard medical image registration procedure for RadID by comparing paranasal sinuses.


Assuntos
Imageamento Tridimensional , Seios Paranasais/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Antropologia Forense/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Sensibilidade e Especificidade
9.
Am J Forensic Med Pathol ; 38(4): 339-344, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28737525

RESUMO

This forensic case presents unique postmortem imaging of a "drug mule" with fatal intoxication due to cocaine leakage on postmortem computed and magnetic resonance (MR) tomography compared with autopsy.Imaging by postmortem computed and MR tomography was performed before autopsy, histology, and toxicology were commissioned. Forensic imaging revealed 91 hyperdense, uniformly shaped body packs with signs of leakage, which was confirmed by autopsy. Postmortem MR imaging displayed the rarely described hypointense appearance of the body packs in T1- and T2-weighted sequences. Toxicology stated the dosage of cocaine intoxication as lethal.This case provides an opportunity to image internal cocaine drug containers on postmortem computed and MR tomography. The cause of death could be determined based on imaging and the radiological morphology of these packs by both imaging methods.


Assuntos
Transporte Intracorporal de Contrabando , Cocaína/intoxicação , Trato Gastrointestinal/diagnóstico por imagem , Trato Gastrointestinal/patologia , Entorpecentes/intoxicação , Autopsia/métodos , Tráfico de Drogas , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada Multidetectores
10.
Forensic Sci Med Pathol ; 13(2): 170-176, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28352988

RESUMO

The aim of the study was to evaluate unenhanced postmortem computed tomography (PMCT) in cases of non-traumatic hemopericardium by establishing the sensitivity, specificity and accuracy of diagnostic criteria for the differentiation between aortic dissection and myocardial wall rupture due to infarction. Twenty six cases were identified as suitable for evaluation, of which ruptured aortic dissection could be identified as the underlying cause of hemopericardium in 50% of the cases, and myocardial wall rupture also in 50% of the cases. All cases underwent a PMCT and 24 of the cases also underwent one or more additional examinations: a subsequent autopsy, or a postmortem magnetic resonance (PMMR), or a PMCT angiography (PMCTA), or combinations of the above. Two radiologists evaluated the PMCT images and classified each case as "aortic dissection", "myocardial wall rupture" or "undetermined". Quantification of the pericardial blood was carried out using segmentation techniques. 17 of 26 cases were correctly identified, either as aortic dissections or myocardial ruptures, by both readers. 7 of 13 myocardial wall ruptures were identified by both readers, whereas both readers identified correctly 10 of 13 aortic dissection cases. Taking into account the responses of both readers, specificity was 100% for both causes of hemopericardium and sensitivity as well as accuracy was higher for aortic dissections than myocardial wall ruptures (72.7% and 87.5% vs 53.8% and 75% respectively). Pericardial blood volumes were constantly higher in the aortic dissection group, but a statistical significance of these differences could not be proven, since the small count of cases did not allow for statistical tests. This study showed that diagnostic criteria for the differentiation between ruptured aortic dissection and myocardial wall rupture due to infarction are highly specific and accurate.


Assuntos
Aneurisma Aórtico/diagnóstico por imagem , Dissecção Aórtica/diagnóstico por imagem , Ruptura Cardíaca/diagnóstico por imagem , Infarto do Miocárdio/diagnóstico por imagem , Derrame Pericárdico/etiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Volume Sanguíneo , Angiografia por Tomografia Computadorizada , Feminino , Patologia Legal , Humanos , Angiografia por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Sensibilidade e Especificidade
11.
AJR Am J Roentgenol ; 208(2): 233-240, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27824494

RESUMO

OBJECTIVE: The 3D volume-rendering technique (VRT) is commonly used in forensic radiology. Its main function is to explain medical findings to state attorneys, judges, or police representatives. New visualization algorithms permit the generation of almost photorealistic volume renderings of CT datasets. The objective of this study is to present and compare a variety of radiologic findings to illustrate the differences between and the advantages and limitations of the current VRT and the physically based cinematic rendering technique (CRT). MATERIALS AND METHODS: Seventy volunteers were shown VRT and CRT reconstructions of 10 different cases. They were asked to mark the findings on the images and rate them in terms of realism and understandability. RESULTS: A total of 48 of the 70 questionnaires were returned and included in the analysis. On the basis of most of the findings presented, CRT appears to be equal or superior to VRT with respect to the realism and understandability of the visualized findings. Overall, in terms of realism, the difference between the techniques was statistically significant (p < 0.05). Most participants perceived the CRT findings to be more understandable than the VRT findings, but that difference was not statistically significant (p > 0.05). CONCLUSION: CRT, which is similar to conventional VRT, is not primarily intended for diagnostic radiologic image analysis, and therefore it should be used primarily as a tool to deliver visual information in the form of radiologic image reports. Using CRT for forensic visualization might have advantages over using VRT if conveying a high degree of visual realism is of importance. Most of the shortcomings of CRT have to do with the software being an early prototype.


Assuntos
Autopsia/métodos , Imageamento Tridimensional/métodos , Tomografia Computadorizada por Raios X/métodos , Interface Usuário-Computador , Gravação em Vídeo/métodos , Medicina Legal , Projetos Piloto
12.
Am J Forensic Med Pathol ; 37(4): 227-230, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27489091

RESUMO

Forensic autopsy is still the criterion standard in legal investigations. Currently, notable transformation is occurring because postmortem imaging is being increasingly endorsed. This article highlights the effectiveness of postmortem computed tomography angiography by using a new contrast medium mixture as a solitary tool to define the cause and manner of death in a ruptured cerebral aneurysm case. Based on the imaging results, autopsy was not mandated and the case was closed.


Assuntos
Aneurisma Roto/diagnóstico por imagem , Angiografia por Tomografia Computadorizada , Meios de Contraste , Aneurisma Intracraniano/diagnóstico por imagem , Evolução Fatal , Feminino , Patologia Legal , Humanos , Soluções Isotônicas , Pessoa de Meia-Idade , Tomografia Computadorizada Multidetectores , Ruptura Espontânea , Hemorragia Subaracnóidea/diagnóstico por imagem , Hemorragia Subaracnóidea/etiologia , Ácidos Tri-Iodobenzoicos
13.
Am J Forensic Med Pathol ; 37(4): 264-269, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27571174

RESUMO

The purpose of this study was to investigate papilledema (PA) as a diagnostic criterion for the presence of antemortem or agonal cerebral edema despite normal postmortem brain swelling on postmortem magnetic resonance imaging (PMMR) in comparison with conventional autopsy.One hundred subjects with head PMMR and autopsy were included in this study. The sensitivities, spec icities, positive predictive values (PPVs), negative predictive values (NPVs), and accuracies were calculated in terms of the PA, PMMR, and cerebral edema on autopsy. Spearman r tests were used to analyze the linear correlations of PA and the radiological and autoptic determination of cerebral edema.In autopsy, the sensitivity regarding the presence of PA and cerebral edema was 66.2% (PPV, 70.5%), and specificity was 48.6% (NPV, 28.3%), with an overall accuracy of 60%. On PMMR, the sensitivity was 86.6% (PPV, 95%). The specificity was 90.9% (NPV, 34%), with an overall accuracy of 88%. The Spearman correlation revealed a statistically significant result (P < 0.001), which indicated a strong linear correlation of the presence of PA and cerebral edema with the autopsy results and the PMMR results.The presence of PA may aid in the diagnoses of cerebral edema despite normal postmortem brain swelling based on PMMR.


Assuntos
Edema Encefálico/diagnóstico , Imageamento por Ressonância Magnética , Papiledema/patologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Causas de Morte , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Mudanças Depois da Morte , Valor Preditivo dos Testes , Estudos Retrospectivos , Sensibilidade e Especificidade , Adulto Jovem
14.
Forensic Sci Med Pathol ; 12(3): 304-11, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27427196

RESUMO

A case of fatal poisoning by ingesting formic acid, diphenhydramine, and ethanol by a 25-year-old woman who committed suicide is presented. Prior to autopsy, postmortem computed tomography and postmortem magnetic resonance tomography were performed and revealed severe damage to the stomach, the left thoracic wall, and parts of the liver. Imaging detected acid-induced fluid-fluid level within the thoracic cavity (fat-equivalent fluid and necrotic pleural effusion). This case report illustrates that postmortem cross-sectional imaging may facilitate dissection of severely damaged or complex regions, and may provide additional information compared to autopsy and toxicological examinations alone.


Assuntos
Queimaduras Químicas/diagnóstico por imagem , Depressores do Sistema Nervoso Central/intoxicação , Difenidramina/intoxicação , Etanol/intoxicação , Formiatos/intoxicação , Hipnóticos e Sedativos/intoxicação , Adulto , Queimaduras Químicas/patologia , Feminino , Patologia Legal , Humanos , Imageamento por Ressonância Magnética , Tomografia Computadorizada Multidetectores , Suicídio
15.
Forensic Sci Med Pathol ; 12(3): 336-42, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27421263

RESUMO

INTRODUCTION: Post-mortem computed tomography guided placement of co-axial introducer needles allows for the extraction of tissue and liquid samples for histological and toxicological analyses. Automation of this process can increase the accuracy and speed of the needle placement, thereby making it more feasible for routine examinations. To speed up the planning process and increase safety, we developed an algorithm that calculates an optimal entry point and end-effector orientation for a given target point, while taking constraints such as accessibility or bone collisions into account. TECHNIQUE: The algorithm identifies the best entry point for needle trajectories in three steps. First, the source CT data is prepared and bone as well as surface data are extracted and optimized. All vertices of the generated surface polygon are considered to be potential entry points. Second, all surface points are tested for validity within the defined hard constraints (reachability, bone collision as well as collision with other needles) and removed if invalid. All remaining vertices are reachable entry points and are rated with respect to needle insertion angle. Third, the vertex with the highest rating is selected as the final entry point, and the best end-effector rotation is calculated to avoid collisions with the body and already set needles. DISCUSSION: In most cases, the algorithm is sufficiently fast with approximately 5-6 s per entry point. This is the case if there is no collision between the end-effector and the body. If the end-effector has to be rotated to avoid collision, calculation times can increase up to 24 s due to the inefficient collision detection used here. In conclusion, the algorithm allows for fast and facilitated trajectory planning in forensic imaging.


Assuntos
Patologia Legal/métodos , Agulhas , Radiografia Intervencionista , Robótica , Manejo de Espécimes/métodos , Algoritmos , Automação , Humanos , Manejo de Espécimes/instrumentação , Tomografia Computadorizada por Raios X
16.
Leg Med (Tokyo) ; 20: 68-74, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27161927

RESUMO

PURPOSE: The purpose of this study was to evaluate the feasibility of diagnosing fatal pulmonary thromboembolism (PTE) with unenhanced postmortem computed tomography (PMCT). MATERIALS AND METHODS: Twelve cases with autopsy confirmed PTE and matched controls (n=19) were retrospectively examined for PTE signs on PMCT. The following variables were evaluated: edema of the lower extremities (areal and Hounsfield Unit measurements) and observer dependent patterns of the morphology of the sedimentation in the pulmonary arteries and trunk. RESULTS: The median absolute difference between the areal measurements of the right and left lower leg and thigh and the attenuation of the popliteal adipose tissue did not differ significantly between the groups. In contrast, the categorical assessment of soft tissue edema in the lower extremities was significantly different. A statistically significant difference could also be found in the shape of the vascular content within the pulmonary trunk and arteries. CONCLUSION: PTE may be assessed on unenhanced PMCT using diagnostic clues such as a distinct pattern of the pulmonary artery content and the presence of perivascular edema in the lower extremities.


Assuntos
Embolia Pulmonar/diagnóstico , Tomografia Computadorizada por Raios X/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Diagnóstico , Estudos de Viabilidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
17.
Leg Med (Tokyo) ; 17(6): 493-8, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26593996

RESUMO

PURPOSE: The aim of this study was to evaluate the utility of cardiac postmortem magnetic resonance (PMMR) to perform routine measurements of the ventricular wall thicknesses and the heart valves and to assess if imaging measurements are consistent with traditional autopsy measurements. METHODS: In this retrospective study, 25 cases with cardiac PMMR and subsequent autopsy were included. The thicknesses of the myocardial walls as well as the circumferences of all heart valves were measured on cardiac PMMR and compared to autopsy measurements. Paired samples T-test and the Wilcoxon-Signed rank test, were used to compare autopsy and cardiac PMMR measurements. For exploring correlations, the Pearson's Correlation coefficient and the Spearman's Rho test were used. RESULTS: Cardiac PMMR measurements of the aortic and pulmonary valve circumferences showed no significant differences from autopsy measurements. The mitral and tricuspid valves circumferences differed significantly from autopsy measurements. Left myocardial and right myocardial wall thickness also differed significantly from autopsy measurements. Left and right myocardial wall thickness, and tricuspid valve circumference measurements on cardiac PMMR and autopsy, correlated strongly and significantly. CONCLUSION: Several PMMR measurements of cardiac parameters differ significantly from corresponding autopsy measurements. However, there is a strong correlation between cardiac PMMR measurements and autopsy measurements in the majority of these parameters. It is important to note that myocardial walls are thicker when measured in situ on cardiac PMMR than when measured at autopsy. Investigators using post-mortem MR should be aware of these differences in order to avoid false diagnoses of cardiac pathology based on cardiac PMMR.


Assuntos
Autopsia , Valvas Cardíacas/anatomia & histologia , Imageamento por Ressonância Magnética , Patologia Legal , Humanos , Mudanças Depois da Morte , Estudos Retrospectivos
18.
Forensic Sci Med Pathol ; 11(4): 589-95, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26434653

RESUMO

PURPOSE: Documentation of forensic radiological observations in postmortem imaging of electrical injuries is not common yet and is less prevalent compared to other forms of burn injuries. However, electrical injuries have high morbidity and mortality. The objective of this case report was the visualization and evaluation of unique electrocution-related injuries by postmortem contrast and non-contrast enhanced imaging compared to a forensic autopsy. METHODS: Forensic imaging included whole-body postmortem computed tomography (PMCT), PMCT-angiography (PMCTA), postmortem magnetic resonance tomography (PMMR), and PMMR-angiography (PMMRA). Initial external inspection and subsequent autopsy were performed. RESULTS: Imaging results revealed intestinal mucosal pathologies, particularly of the gastric vascular integrity and remarkable rhabdomyolysis of the striated muscles of the extremities. Furthermore, PMCT and PMCTA revealed a hepatic lesion with perihepatic free fluid. The results from external inspection and autopsy correlated to the well-known pathologies of electrocution in the course of a high-voltage incident. CONCLUSION: Postmortem imaging visualized electrocution-related injuries and aided substantially in the medico-legal investigation. These findings, particularly of the rhabdomyolysis in magnetic resonance tomography, may support the future image interpretation of cases with electrical injuries-in the living and the deceased.


Assuntos
Diagnóstico por Imagem , Traumatismos por Eletricidade/diagnóstico por imagem , Traumatismos por Eletricidade/patologia , Imagem Corporal Total , Adulto , Intoxicação Alcoólica/complicações , Evolução Fatal , Patologia Legal , Humanos , Imageamento Tridimensional , Masculino , Radiografia , Rabdomiólise/patologia
19.
Am J Forensic Med Pathol ; 36(3): 153-61, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26132433

RESUMO

PURPOSE: In traumatic brain injury, diffusion-weighted and diffusion tensor imaging of the brain are essential techniques for determining the pathology sustained and the outcome. Postmortem cross-sectional imaging is an established adjunct to forensic autopsy in death investigation. The purpose of this prospective study was to evaluate postmortem diffusion tensor imaging in forensics for its feasibility, influencing factors and correlation to the cause of death compared with autopsy. METHODS: Postmortem computed tomography, magnetic resonance imaging, and diffusion tensor imaging with fiber tracking were performed in 10 deceased subjects. The Likert scale grading of colored fractional anisotropy maps was correlated to the body temperature and intracranial pathology to assess the diagnostic feasibility of postmortem diffusion tensor imaging and fiber tracking. RESULTS: Optimal fiber tracking (>15,000 fiber tracts) was achieved with a body temperature at 10°C. Likert scale grading showed no linear correlation (P > 0.7) to fiber tract counts. No statistically significant correlation between total fiber count and postmortem interval could be observed (P = 0.122). Postmortem diffusion tensor imaging and fiber tracking allowed for radiological diagnosis in cases with shearing injuries but was impaired in cases with pneumencephalon and intracerebral mass hemorrhage. CONCLUSIONS: Postmortem diffusion tensor imaging with fiber tracking provides an exceptional in situ insight "deep into the fibers" of the brain with diagnostic benefit in traumatic brain injury and axonal injuries in the assessment of the underlying cause of death, considering influencing factors for optimal imaging technique.


Assuntos
Lesões Encefálicas/patologia , Imagem de Tensor de Difusão , Fibras Nervosas/patologia , Adolescente , Adulto , Idoso , Axônios/patologia , Temperatura Corporal , Encéfalo/patologia , Estudos de Viabilidade , Feminino , Patologia Legal , Humanos , Masculino , Pessoa de Meia-Idade , Mudanças Depois da Morte , Estudos Prospectivos , Substância Branca/patologia , Adulto Jovem
20.
Forensic Sci Med Pathol ; 11(2): 162-7, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25724838

RESUMO

The aim of this study was to evaluate the diagnostic criteria and to identify the radiological signs (derived from known radiological signs) for the detection of aortic dissections using postmortem computed tomography (PMCT). Thirty-three aortic dissection cases were retrospectively evaluated; all underwent PMCT and autopsy. The images were initially evaluated independently by two readers and were subsequently evaluated in consensus. Known radiological signs, such as dislocated calcification and an intimomedial flap, were identified. The prevalence of the double sedimentation level in the true and false lumen of the dissected aorta was assessed and defined as a postmortem characteristic sign of aortic dissection. Dislocated calcification was detected in 85% of the cases with aortic calcification; whereas in 54% of the non-calcified aortas, the intimomedial flap could also be recognized. Double sedimentation was identified in 16/33 of the cases. Overall, in 76% (25/33) of the study cases, the described signs, which are indicative for aortic dissection, could be identified. In this study, three diagnostic criteria of aortic dissection were identified using non-enhanced PMCT images of autopsy-confirmed dissection cases.


Assuntos
Aorta/lesões , Aortografia , Autopsia/métodos , Tomografia Computadorizada por Raios X , Sedimentação Sanguínea , Patologia Legal , Humanos , Estudos Retrospectivos , Túnica Íntima/diagnóstico por imagem , Túnica Íntima/lesões , Túnica Média/diagnóstico por imagem , Túnica Média/lesões , Calcificação Vascular/diagnóstico por imagem
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