RESUMO
The intestinal absorption of doses of vitamin B12 and of niacin was examined in 6, 12, and 24 months old female Wistar rats. Rats were dosed via stomach tube with radioactive forms of the vitamins and were killed 16 hours later. Percent of the dose remaining in the stomach and gastrointestinal tract and in the collected feces was determined. Absorption of the two vitamins was not influenced by the age of the animals.
Assuntos
Envelhecimento , Absorção Intestinal , Ácidos Nicotínicos/metabolismo , Vitamina B 12/metabolismo , Administração Oral , Animais , Feminino , Ratos , Ratos EndogâmicosRESUMO
The absorption of vitamins A and D was examined in 6, 12, and 24 months old female Wistar rats. Animals were dosed by stomach tube with radioactive forms of vitamins A and D and killed 18 hours later. Isotope in feces collected during this time and isotope remaining in the gastrointestinal tract were determined and subtracted from total dose to determine percentage of absorption. Under the conditions of this study, age had no significant effect on the absorption of vitamins A and D.