Análisis de la relación entre la proporción áurea y el parámetro facial / Analysis of the relation between the golden ratio and the facial parameter

Introducción: la habilidad clínica para modificar la forma dentofacial a través del tratamiento ortodóntico, cirugía maxilofacial o cirugía plástica, requiere comprensión de la belleza facial, incluyendo la evaluación de la estética facial, proporciones y simetría. Objetivo: analizar la relación entre los componentes de la proporción áurea con el parámetro facial de estudiantes en la provincia Chiclayo. Métodos: la población de estudio fue representada por 88 estudiantes que cumplieron con los siguientes criterios de inclusión: edad entre 17-28 años, ambos sexos, sin tratamiento ortodóntico, con maloclusión clase I y dentición completa. Se diseñó una ficha de recolección de datos para medidas antropométricas craneofaciales. Se calibraron los examinadores, se evaluó la estabilidad de la concordancia intra e interexaminador mediante el coeficiente Kappa de Cohen. Para el contraste de la hipótesis se utilizó el coeficiente de correlación chi cuadrado. Para todas las pruebas estadísticas el nivel de significancia fue de 5 por ciento (p< 0,05). Resultados: se observó que el 65,91 por ciento del total de pacientes presentaban proporción divina en su dimensión externa, 48,86 por ciento son braquifaciales, 13,64 por ciento mesofaciales, 3,41 por ciento dolicofaciales, y el 57,95 por ciento del total presentaban proporción divina en su relación vertical, 42,05 por ciento son braquifaciales, 10,23 por ciento mesofaciales y 5,68 por ciento dolicofaciales. En cuanto al perfil armónico, el 70,45 por ciento del total de pacientes no presenta proporción divina, de los cuales el 53,41 por ciento son braquifaciales, 10,23 por ciento son mesofaciales y 6,82 por ciento son dolicofaciales. Conclusiones: solo existe relación entre la proporción áurea en su componente de dimensión externa con el parámetro facial. La proporción áurea se cumplió en todos sus componentes, en un mayor porcentaje en los individuos braquifaciales y hubo predominio de la proporción áurea en el sexo femenino(AU)

Introduction: the clinical ability to modify the dentofacial form through orthodontic treatment, maxillofacial surgery, or plastic surgery requires an understanding of facial beauty, including the evaluation of facial aesthetics, proportions, and symmetry. Objective: to analyze the relationship between the components of the golden ratio and the facial parameter of students in the province of Chiclayo. Methods: the study population was represented by 88 students who met the following inclusion criteria: age between 17 and 28 years, both sexes, without orthodontic treatment, with class I malocclusion and complete dentition. A data collection form for craniofacial anthropometric measurements was designed. The examiners were calibrated, the stability of the intra- and inter-rater concordance was evaluated using the Cohen's Kappa coefficient. For the contrast of the hypothesis, the correlation coefficient square chi was used. For all statistical tests, the level of significance was 5 percent (p< 0.05). Results: 65.91 percent of all the patients were observed to have a divine proportion in their external dimension: 48.86 percent are brachifacial, 13.64 percent mesofacial, and 3.41 percent dolichofacial. 57.95 percent of the total number of patients presented divine proportion in its vertical relation: 42.05 percent are brachifacial, 10.23 percent mesofacial, and 5.68 percent dolichofacial. Regarding the harmonic profile, 70.45 percent of the total number of patients did not present a divine proportion: 53.41 percent are brachifacial, 10.23 percent are mesofacial, and 6.82 percent are dolichofacial. Conclusions: there is only a relationship between the golden ratio in its external dimension component and the facial parameter. The golden ratio was fulfilled in all its components, in a greater percentage in the brachifacial individuals, and there was a predominance of the golden ratio in the female sex(AU)

Análisis de la relación entre la proporción áurea y el parámetro facial / Analysis of the relation between the golden ratio and the facial parameter

Introducción: la habilidad clínica para modificar la forma dentofacial a través del tratamiento ortodóntico, cirugía maxilofacial o cirugía plástica, requiere comprensión de la belleza facial, incluyendo la evaluación de la estética facial, proporciones y simetría. Objetivo: analizar la relación entre los componentes de la proporción áurea con el parámetro facial de estudiantes en la provincia Chiclayo. Métodos: la población de estudio fue representada por 88 estudiantes que cumplieron con los siguientes criterios de inclusión: edad entre 17-28 años, ambos sexos, sin tratamiento ortodóntico, con maloclusión clase I y dentición completa. Se diseñó una ficha de recolección de datos para medidas antropométricas craneofaciales. Se calibraron los examinadores, se evaluó la estabilidad de la concordancia intra e interexaminador mediante el coeficiente Kappa de Cohen. Para el contraste de la hipótesis se utilizó el coeficiente de correlación chi cuadrado. Para todas las pruebas estadísticas el nivel de significancia fue de 5 por ciento (p< 0,05). Resultados: se observó que el 65,91 por ciento del total de pacientes presentaban proporción divina en su dimensión externa, 48,86 por ciento son braquifaciales, 13,64 por ciento mesofaciales, 3,41 por ciento dolicofaciales, y el 57,95 por ciento del total presentaban proporción divina en su relación vertical, 42,05 por ciento son braquifaciales, 10,23 por ciento mesofaciales y 5,68 por ciento dolicofaciales. En cuanto al perfil armónico, el 70,45 por ciento del total de pacientes no presenta proporción divina, de los cuales el 53,41 por ciento son braquifaciales, 10,23 por ciento son mesofaciales y 6,82 por ciento son dolicofaciales. Conclusiones: solo existe relación entre la proporción áurea en su componente de dimensión externa con el parámetro facial. La proporción áurea se cumplió en todos sus componentes, en un mayor porcentaje en los individuos braquifaciales y hubo predominio de la proporción áurea en el sexo femenino(AU)

Introduction: the clinical ability to modify the dentofacial form through orthodontic treatment, maxillofacial surgery, or plastic surgery requires an understanding of facial beauty, including the evaluation of facial aesthetics, proportions, and symmetry. Objective: to analyze the relationship between the components of the golden ratio and the facial parameter of students in the province of Chiclayo. Methods: the study population was represented by 88 students who met the following inclusion criteria: age between 17 and 28 years, both sexes, without orthodontic treatment, with class I malocclusion and complete dentition. A data collection form for craniofacial anthropometric measurements was designed. The examiners were calibrated, the stability of the intra- and inter-rater concordance was evaluated using the Cohen's Kappa coefficient. For the contrast of the hypothesis, the correlation coefficient square chi was used. For all statistical tests, the level of significance was 5 percent (p< 0.05). Results: 65.91 percent of all the patients were observed to have a divine proportion in their external dimension: 48.86 percent are brachifacial, 13.64 percent mesofacial, and 3.41 percent dolichofacial. 57.95 percent of the total number of patients presented divine proportion in its vertical relation: 42.05 percent are brachifacial, 10.23 percent mesofacial, and 5.68 percent dolichofacial. Regarding the harmonic profile, 70.45 percent of the total number of patients did not present a divine proportion: 53.41 percent are brachifacial, 10.23 percent are mesofacial, and 6.82 percent are dolichofacial. Conclusions: there is only a relationship between the golden ratio in its external dimension component and the facial parameter. The golden ratio was fulfilled in all its components, in a greater percentage in the brachifacial individuals, and there was a predominance of the golden ratio in the female sex(AU)

Antinociceptive Activity of Ent-Dihydrotucumanoic Acid Isolated from Gymnosperma glutinosum Spreng Less.

Preclinical Research The diterpene ent-dihydrotumanoic acid (DTA) was among the compounds isolated from Gymnosperma glutinosum (Spreng) Less (Asteraceae). There are no reports regarding the pharmacological effects of DTA. Cytotoxicity against cancer cells (1-250 µM), and the antibacterial (50-1400 µM) activity of DTA were evaluated using the MTT assay, and the minimum inhibitory concentration test, respectively. The antidiarrheal (1-100 mg/kg p.o.) and anti-inflammatory (2 mg/ear) effects of DTA were evaluated using castor oil and 12-O-tetradecanoylphorbol-13-acetate, respectively. The antinociceptive and sedative effects of DTA (1-100 mg/kg p.o.) were evaluated using two models of chemically-induced nociception, and the pentobarbital-induced sleeping time test, respectively. The antinociceptive mechanism of DTA was evaluated using the acetic acid writhing test with inhibitors related to pain processing pathways. The effects of DTA (10-100 mg/kg p.o.) on locomotor activity were evaluated using the rotarod test. DTA lacked cytotoxic activity (IC50 > 100 µM) on cancer cells, possessed moderate antibacterial effects against B. subtillis (MIC= 175 µM), moderate antidiarrheal and anti-inflammatory effects, and minimal vasorelaxant effects. In the formalin test, DTA showed antinociceptive effects in both phases. In the acetic acid test, DTA showed antinociceptive activity (ED50 = 50.2 ± 5.6 mg/kg) with potency similar to that of naproxen (NPX; ED50 =33.7 ± 4.5 mg/kg) an effect blocked by naloxone implicating an opioid mechanism. DTA also exerted antidiarrheal activity and showed no sedative effects or changes in locomotor activity in mice. Drug Dev Res 78 : 340-348, 2017. © 2017 Wiley Periodicals, Inc.

An eco-epidemiological study of contamination of soil with infective forms of intestinal parasites.

The objectives of the present work were to screen topsoil samples collected from public squares in two cities within the Argentine Patagonia for the presence of infective forms of intestinal parasites and to examine the possible relationship between positive findings and the environmental, socioeconomic, and cultural conditions of that region. For this purpose we studied 13 public squares, their 13 custodians, and 44 family groups within their respective surrounding areas. Of the 226 topsoil samples analyzed, 44.3% proved positive for infective forms of intestinal parasites, with 17.3% of these containing more than one species. The frequency of appearance of positive samples was dependent on the season of the year (p < 0.001), while presence of the parasites was related to the soil pH (p < 0.05) but independent of the soil relative humidity (p > 0.05). Some of the organisms detected are associated with zoonoses. We observed the presence of Capillaria spp. and Spirocerca spp. under cool desert climatic conditions. Within the group of custodians we detected hematologic alterations one positive serology for toxoplasmosis and documented behavior conducive to risk of infection with the parasites found in those squares. Within the family group an acquaintance with parasitic zoonoses and their prevention was an inconsistent finding, with toxocarosis and toxoplasmosis being the diseases associated with the greatest degree of ignorance. Furthermore, we consider the failure to de-parasitize pets and the practice of feeding them with raw meat, as typically found in our family survey, to be factors contributing to a greater likelihood of public square contamination. From the results obtained here, we propose a spatial organization approach for the purpose of detecting zones at risk of contracting zoonotic parasitoses within urban environments.

La giardiasis en relación con el grupo sanguíneo A / Giardiasis in relation to blood group A

Los informes contradictorios acerca de la asociación entre el grupo sanguíneo A y giardiasis, motivaron a los autores a investigar este problema en una muestra de 757 niños, de los cuales 385 tenían quistes de giardia en las heces. Por otro lado, se colectó la información que a este respecto existe en la literatura médica y se analizaron los datos empleando un procedimiento estadístico que ha sido sugerido para investigar la relación entre grupos sanguíneos y enfermedad. Los datos recabados y el análisis de la información obtenida en la literatura, permiten estimar que por cada 100 personas del grupo O con G. lamblia existen 143 del grupo A, es decir que el riesgo de enfermar en estos últimos es 43% más alto