[Neonatal encephalitis caused by herpes simplex: immunohistochemical diagnosis of a case]. / Encefalite neo-natal pelo vírus do herpes simplex: diagnóstico imuno-histoquímico de um caso.

The authors report the case of a female newborn infant, who had seizures and vesicles at the nose and inferior lip since the fifth day of life. CSF changes suggested an encephalitis. Signs of neurologic and respiratory deterioration were followed by death. Partial cranial autopsy showed a necrohemorrhagic temporal encephalitis without intranuclear inclusions. Immunohistochemical examination by the avidin-biotin-peroxidase technique with polyclonal antibodies against Herpes simplex type 1 and type 2 was positive to type 2 Herpes simplex virus.

[Progressive infantile spinal muscular atrophy. Report of 12 cases]. / Atrofia muscular espinhal infantil progressiva. Relato de 12 casos.

Twelve children with progressive spinal muscular atrophy were seen at Santo Antonio Children Hospital, Porto Alegre. Diagnosis was based on neurological evaluation, serum enzymes, electroneuromyography and muscle biopsy. Several aspects are discussed by the authors, especially those concerning the presentation mode of the illness and the laboratory investigation. Our results are reviewed under the light of the current literature.

"Hallervorden-Spatz syndrome--infantile neuroaxonal dystrophy" complex. Case report.

Case report of a 7 1/2-year-old girl considered as being normal until the age of 2 years. From then on she progressed with gait disturbance, mental deterioration, dystonic movements, convulsions and dysarthria. She died of bronchopneumonia one year later. CT scan showed hyperdensity at the putamen, with no signs of cerebral atrophy. Pathological examination disclosed an intense red coloration of the putamen and axonal "spheroids" at electron microscopy.

[Neurocryptococcosis in childhood. Report of 3 cases in the 1st decade of life]. / Neurocriptococose na infância. Relato de três casos na primeira décade de vida.

The authors report three cases of central nervous system cryptococcosis in children in the first decade of life, from Rio Grande do Sul State, Brazil. Diagnosis was supported by demonstration of Cryptococcus neoformans with India-ink preparations of the spinal fluid and Sabouraud's media culture. Clinical presentation included acute, subacute and chronic forms. Increased intracranial pressure and hydrocephalus were the complications during the course of the disease, and a ventriculoperitoneal shunt was used in one case. Undernutrition was associated with all cases and tubercle bacillus infection with one. Specific therapy was administered to the three patients. One patient was cured and the other two died.

Intoxicacao por metoclopramida. / Intoxication by metoclopramide

Sao analisados 13 casos de intoxicacao por metoclopramida, internados na Emergencia do Hospital da Crianca Santo Antonio, no periodo de janeiro de 1981 a dezembro de 1982. Sao considerados a dose, a via de administracao, o tempo de inicio dos sintomas e as manifestacoes clinicas. E enfatizado o cuidado necessario quanto a via de administracao e, principalmente, a dose maxima, que nao deve exceder a 0,5mg/kg/ dia.