Clinical display, diagnostics and genetic implication of novel Coronavirus (COVID-19) epidemic.

COVID-19 pandemic can cause irreparable damage to the involved society. This study aimed to provide a summary of the up-to-dated clinical display, diagnostics, molecular and genetic implications for COVID-19 infected patients. In this review, 73 research articles published before 25 March 2020 were analyzed to better understand the clinical characteristics of patients and to introduce the available serological, hematology and molecular diagnostic methods. Apart from articles extracted from PubMed and Google Scholar, WHO (https://www.who.int/), NHC (National Health Commission of the People's Republic of China (http://www.nhc.gov.cn/), NICE (National Institute for Health and Clinical Excellence, https://www.nice.org.uk/), CDC (Centers for Disease Control and Prevention, https://www.cdc.gov/), and National Administration of Traditional Chinese Medicine (http://www.satcm.gov.cn/) were also accessed to search for eligible studies. Papers published between January 1, 2020, and 25 March 2020 were searched in English and the terms "2019-nCoV, Covid-19, Clinical Characteristics OR manifestation, method of detection, COVID-19 Genome and molecular test" were used. As the pandemic continues to evolve, there have been reports about the possibility of asymptomatic transmission of this newly emerged pneumonia virus. We highlighted the role of HLA haplotype in virus infection as HLA typing will provide susceptibility information for personalized prevention, diagnosis, and treatment in future studies. All the data in this article will assist researchers and clinicians to develop their clinical views regarding infected patients and to emphasize the origin of SARS-CoV-2 for diagnostics.

Integrating organizational development skills with community organization practice: the key to successful national health care programs.

The article describes the developmental stages of a health care project from the inception as a demonstration project until its establishment as a large scale national program. The skills and competencies required of a project administrator during the demonstration stage are more related to the practice of community organization. However, in expanding a demonstration project to a large scale national program, these administrators are confronted with a multitude of bureaucratic and organizational constraints. The skills and competencies required of a program manager at this stage are best grouped under the field of organizational development. The failure of many large programs can be traced to the lack of organizational development skills among those involved in managing them. The implications for organizational development training within the curriculum of instruction in health education are also discussed.

Broncho-aortic fistula secondary to pulmonary tuberculosis.

Tuberculous broncho-aortic fistula has not been reported, to our knowledge. This is a case report of a 60-year-old woman with massive hemoptysis secondary to a broncho-aortic fistula. The pathologic study of the pulmonary specimens showed tuberculous granulomas with caseous necrosis and tubercle bacilli in the pulmonary tissue and the fistulous area.