Differences in mother-to-infant bonding according to type of C-section: Elective versus unplanned.

Aim To compare the mother-to-infant bond of mothers who gave birth by elective C-section versus urgent C-section in the first 48-72h of life and 10-12weeks after delivery. METHODS: This is a cohort prospective study of women giving birth by C-section. 48-72h after delivery, sociodemographic variables were collected, Mother-to-Infant Bonding Scale and newborn's response to separation test were performed. 10-12weeks after delivery Mother-to-Infant Bonding Scale and questions about baby's feeding were completed. RESULTS: A total of 116 dyads were recruited, 58 in each group. No significant differences between the two C-sections in bonding, newborn response to separation or type of feeding were observed at any time points. However, those dyads presenting with an abnormal bond at time 1 had more frequently an abnormal bond at time 2 (50% versus 8.1%, p=0.000). CONCLUSIONS: No differences in mother-to-infant bond were found according to type of C-section.

Prevalence and Risk Factors of Prolonged Corrected QT Interval Among Children and Adolescents Treated With Antipsychotic Medications: A Long-Term Follow-Up in a Real-World Population.

PURPOSE: This study aimed to describe the prevalence of corrected QT (QTc) interval disorders and the possible predisposing factors in children and adolescents treated with antipsychotic (AP) medications in a real-world population with a long-term follow-up. METHODS: Data were obtained from the SafEty of NeurolepTics in Infancy and Adolescence (SENTIA) registry (https://sentia.es). The SENTIA includes patients younger than 18 years who are currently taking or initiating treatment with AP medications and have agreed to participate in the registry. The SENTIA's follow-up includes an electrocardiogram (ECG) assessment before starting treatment and at 1, 3, and 6 months after treatment initiation or after any changes in the patient's AP medication treatment. Thereafter, all participants undergo an ECG every 6 months. A QTc interval more than 450 milliseconds, increases in QTc interval of 60 milliseconds or more, or QTc dispersion more than 100 milliseconds were considered abnormal. RESULTS: Since January 1, 2011, 101 patients have been enrolled in SENTIA and have had at least 1 ECG assessment. The mean age at inclusion was 11.5 years; 75% of the patients were men. The mean follow-up time was 20.0 ± 15.1 months. The most frequently prescribed AP medications were risperidone (52.2%) and aripiprazole (45.5%). Seven patients (6.9%) had abnormal changes in QTc. No patient had a QTc interval more than 500 milliseconds. All patients were asymptomatic. The QTc changes were observed at different times of exposure, with a range of 1 to 39 months after beginning AP treatment. Concomitant use of attention deficit and hyperactivity disorder drugs seemed a possible factor associated with QTc disorders. CONCLUSIONS: Patients should undergo a baseline ECG assessment before starting AP medication treatment, particularly patients with concomitant use of attention deficit and hyperactivity disorder drugs or a family/personal history of heart disease.

Trastorno límite de la personalidad y conductas autolíticas / Borderline personality disorder and self-harming behaviors

En este artículo se rastrean los factores de riesgo de suicidio en pacientes con diagnóstico de trastorno límite de la personalidad y se propone un abordaje de diagnóstico exhaustivo. Se realizó una búsqueda bibliográfica en PubMed (desde 2007) con las palabras clave (en inglés) «trastorno límite de la personalidad», «suicidio» y «conductas autolíticas». A partir de los resultados, se elaboraron las siguientes conclusiones: 1) las conductas autolesivas no autolíticas se diferencian de los intentos letales de suicidio en pronóstico y en rasgos de personalidad; 2) hay resultados contradictorios, probablemente porque el trastorno límite de la personalidad es una categoría heterogénea; y 3) el riesgo global de suicidio consumado en estos pacientes es elevado y los actuales criterios diagnósticos (DSM-IV-TR) son insuficientes para capturar los indicadores de riesgo asociados (afección comórbida, entorno y rasgos de personalidad). Finalmente se propone una exploración topográfica de la personalidad, que incluye aspectos relevantes no capturados por el DSM-IV(AU)

This review explores suicide risk factors in patients diagnosed with borderline personality disorder and proposes a comprehensive diagnostic assessment. A literature search in PubMed (since 2007) was performed, with the following key word search: "borderline personality disorder", "suicide", and "self-harming behaviour". With the selected articles, the following conclusions were drawn up: 1) self harming behaviors are different to lethal suicide attempts in terms of prognosis and personality traits; 2) there are controversial results, probably explained by the fact that borderline personality disorder is an heterogeneous category; and 3) the global risk of completed suicide in these patients is high and the current diagnostic criteria (DSM-IV-TR) do not take into account the associated risk factors (comorbidities, environment, personality traits). Lastly, a topographic assessment of personality, including those aspects not present in the DSM, is proposed(AU)