Collaborative practice competencies needed for telehealth delivery by health and social care professionals: a scoping review.

In the context of the COVID-19 pandemic, many healthcare and social services professionals have had to provide services through virtual care. In the workplace, such professionals often need to be sufficiently resourced to collaborate and address collaborative care barriers in telehealth. We performed a scoping review to identify the competencies required to support interprofessional collaboration among clinicians in telehealth. We followed Arksey and O'Malley's and the Joanna Briggs Institute's methodological guidelines, including quantitative and qualitative peer-reviewed articles published between 2010 and 2021. We expanded our data sources by searching for any organization or experts in the field via Google. The analysis of the resulting thirty-one studies and sixteen documents highlighted that health and social services professionals are generally unaware of the competencies they need to develop or maintain interprofessional collaboration in telehealth. In an era of digital innovations, we believe this gap may jeopardize the quality of the services offered to patients and needs to be addressed. Of the six competency domains in the National Interprofessional Competency Framework, it was observed that interprofessional conflict resolution was the competency that emerged least as an essential competency to be developed, while interprofessional communication and patient/client/family/community-centered care were identified as the two most reported essential competencies.

Investigating a new C2-symmetric testosterone dimer and its dihydrotestosterone analog: Synthesis, antiproliferative activity on prostate cancer cell lines and interaction with CYP3A4.

The synthesis of a 17α-linked C2-symmetric testosterone dimer and its dihydrotestosterone analog is reported. The dimers were synthesized using a short five-step reaction sequence with 28% and 38% overall yield for the testosterone and dihydrotestosterone dimer, respectively. The dimerization reaction was achieved by an olefin metathesis reaction with 2nd generation Hoveyda-Grubbs catalyst. The dimers and their corresponding 17α-allyl precursors were tested for the antiproliferative activity on androgen-dependent (LNCaP) and androgen-independent (PC3) prostate cancer cell lines. The effects on cells were compared with that of the antiandrogen cyproterone acetate (CPA). The results showed that the dimers were active on both cell lines, with an increased activity towards androgen-dependent LNCaP cells. However, the testosterone dimer (11) was fivefold more active than the dihydrotestosterone dimer (15), with an IC50 of 11.7 µM vs. 60.9 µM against LNCaP cells, respectively, and more than threefold more active than the reference drug CPA (IC50 of 40.7 µM). Likewise, studies on the interaction of new compounds with drug-metabolizing cytochrome P450 3A4 (CYP3A4) showed that 11 was a fourfold stronger inhibitor than 15 (IC50 of 3 µM and 12 µM, respectively). This suggests that changes in the chemical structure of sterol moieties and the manner of their linkage could largely affect both the antiproliferative activity of androgen dimers and their crossreactivity with CYP3A4.

The Associations between Self-Silencing and Delinquency in Adolescent Who Experienced Child Sexual Abuse.

A large body of research reveals that child sexual abuse is an adverse experience associated with many negative socioemotional and behavioral consequences during adolescence. Notably, adolescent victims of child sexual abuse are more likely to engage in delinquent behavior, which has importance for their adaptation later in life. While research on the psychological antecedents of delinquent behavior has independently considered each core feature of silencing the self (i.e., low assertiveness and self-expression, conflict avoidance, presenting a non-authentic self, anger, and hostility), it has failed to jointly consider these as potential predictors of delinquent behaviors in adolescent victims of child sexual abuse. The purpose of this study was to examine the associations between the two dimensions of self-silencing (i.e., divided self and silencing the self) and delinquency in adolescent victims of child sexual abuse. A sample of 110 adolescents seeking services following child sexual abuse completed self-reported questionnaires, and case files were analyzed to gather information regarding child sexual abuse severity. Hierarchical regression analyses revealed that, after controlling for the effect of age, gender, parental monitoring, and child sexual abuse severity, self-silencing was positively associated with delinquent behaviors, affiliation with delinquent peers, as well as alcohol and drug use. Divided self contributed to the prediction of aggressive behaviors. Implementing interventions aimed at increasing adolescents' assertiveness, conflict management skills, and emotion regulation and promoting congruence between their behaviors and authentic selves may lower their involvement in delinquency.

History of trauma and COVID-19-related psychological distress and PTSD.

The COVID-19 pandemic has a great impact on society as a whole. Yet the pandemic and associated mandatory lockdown in several countries may have increased the vulnerability of certain populations. The present study aimed to document the frequency of clinical level of psychological distress and COVID-19 related post-traumatic stress symptoms in youth during the first wave of the pandemic. The study more specifically explored the role of prior trauma and adverse life events as a vulnerability factor for negative outcomes. A sample of 4914 adolescents and young adults from the province of Quebec, Canada was recruited online through social networks during the first wave of COVID-19. Results revealed that 26.6% of youth displayed serious psychological distress and 20.3% probable PTSD symptoms. The number of past traumas and adversity experienced showed a dose-response relation with the prevalence of psychological distress and PTSD. After controlling for socio-demographic characteristics and COVID-19 related variables (exposure, fear, suspicion of having the infection), participants with a history of five traumas and more presented a two-fold risk of serious psychological distress and probable PTSD. Emotion dysregulation was also associated with an increased risk of symptoms while resilience was linked to a reduced risk of distress.

Relationship quality among dating adolescents: Development and validation of the Relationship Quality Inventory for Adolescents.

Relationship quality has implications for individuals' and couples' wellbeing, such as higher couple functioning and perceived quality of life. In adolescence, low relationship quality has been associated with poor mental health and relational outcomes. However, given the lack of instruments to assess satisfaction in dating relationships, most studies have relied on measures of marital satisfaction. The current study aimed to address this gap by elaborating and validating the Relationship Quality Inventory for Adolescents (RQI-A). Exploratory and confirmatory factor analyses were conducted among two samples of French-speaking dating adolescents (n 1 = 310; n 2 = 335). The two-factor structure (Connectedness and Commitment) was cross-validated, and dimensions showed high internal consistency coefficients (ω = 0.86-0.89). Results also provide evidence of convergent validity of the scale with related measures. The RQI-A may help study predictors and correlates of dating relationship quality.

Development and validation of the Relational Skills Inventory for Adolescents.

INTRODUCTION: Dating violence prevention initiatives are intended, not only to reduce the occurrence of violent behaviors, but also to promote the development of positive dating relational skills starting in adolescence. However, despite the growing interest in examining adolescent relational skills in adolescents, no specific measure is yet available to assess post program gains relative to dating violence prevention and intervention. The current study addressed this important gap in dating relationships research by developing and validating a new measure of relational skills for adolescents. METHODS: Exploratory and confirmatory factor analyses were conducted on two samples of French-speaking dating adolescents from Quebec, Canada (n1= 384; n2= 687). RESULTS: Exploratory factor analysis revealed a three-factor structure reflecting constructs of Assertiveness, Support and Individuality (α = 0.69-0.81). Results also support evidence of convergent validity with related measures. The three-factor structure was cross-validated among a second sample (α = 0.74-0.79). Two-way ANCOVAs were also conducted to examine differences in levels of relational skills as a function of sex and previous dating violence perpetration. Results indicated that girls reported higher levels of assertiveness than boys, and that adolescents who reported the use of dating violence also reported lower levels of all relational skills. CONCLUSION: The validation of the Relational Skills Inventory for Adolescents (RSI-A) will help researchers assess the effectiveness of interventions aimed at promoting the development of positive dating relationships during adolescence.