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Rev Cubana Med Trop ; 58(3): 248-53, 2006.
Artigo em Espanhol | MEDLINE | ID: mdl-23424794

RESUMO

A prospective and descriptive study of 20 patients infected with HIV and admitted to "Pedro Kouri" Institute of Tropical Disease after a diagnosis of lymphoma was conducted. They were all evaluated at the onset of diagnosis by a thorough medical record exam and supportive studies such as complete blood count, globular sedimentation speed, CD4+ count, lactic acid dehydrogenase, HIV viral load, cytology and biopsy. Of this number, 85% presented with CD4+ count under 350 cell/mm3 at the time of diagnosis; however, only 55% showed viral loads exceeding 50,000 copies/mL. The predominant histological subtype was large diffuse cells and the most frequent location was the extrapulmonary site in 70% of cases. It called our attention that high levels of lactic acid dehydrogenase and extrapulmonary location of tumors were related. Statistically significant association was found (p < 0.05) between immunosuppresion condition of the patients given by CD4+ count below 350 cell/mm3 and advanced staging of the tumoral disease (stages III and IV).


Assuntos
Linfoma Relacionado a AIDS/epidemiologia , Academias e Institutos , Adulto , Biomarcadores Tumorais/sangue , Sedimentação Sanguínea , Contagem de Linfócito CD4 , Cuba/epidemiologia , Etnicidade/estatística & dados numéricos , Feminino , Humanos , Hospedeiro Imunocomprometido , L-Lactato Desidrogenase/sangue , Linfoma Relacionado a AIDS/sangue , Linfoma Relacionado a AIDS/imunologia , Linfoma Relacionado a AIDS/patologia , Masculino , Estadiamento de Neoplasias , Estudos Prospectivos , Fatores de Risco , Carga Viral , Viremia/epidemiologia , Adulto Jovem
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