Assuntos
Doenças do Colo/complicações , Obstrução Intestinal/complicações , Adulto , Sulfato de Bário , Colo/patologia , Doenças do Colo/diagnóstico por imagem , Doenças do Colo/patologia , Enema , Feminino , Humanos , Obstrução Intestinal/diagnóstico por imagem , Obstrução Intestinal/patologia , RadiografiaRESUMO
Tuberculosis of the skull vault is very rare and recently has only been reported from Africa. Two cases have presented in the city of Bradford during the past 10 years, both in young Asians. The radiology is discussed.
Assuntos
Crânio/diagnóstico por imagem , Tuberculose Osteoarticular/diagnóstico por imagem , Adolescente , Ásia/etnologia , Criança , Diagnóstico Diferencial , Inglaterra , Humanos , Masculino , RadiografiaRESUMO
A preterm baby boy with blood and bone changes of copper deficiency is described. Copper deficiency was suspected after fracture of the left femur during examination of the hip joint. A low serum copper concentration (2.7 mumol/l; 17.2 micrograms/100 ml) and caeruloplasmin (0.04 g/l; 0.004 g/100 ml) confirmed the diagnosis. Despite the introduction of solids at 18 weeks the copper concentration remained low, and treatment with copper sulphate (2.5 mg daily) was started at 6 months. Treatment was stopped at 9 months, when he was both physically and developmentally normal. When given a choline-containing vitamin preparation (Ketovite) he developed a fish odour because of the accumulation of trimethylamine. Withdrawal of this preparation at 6 weeks and substitution with a choline-free preparation (Abidec) was soon followed by disappearance of the odour. It is speculated that prematurity rather than copper deficiency was responsible for the poor activity of liver enzyme, trimethylamine oxidase.
Assuntos
Cobre/deficiência , Fraturas do Fêmur/etiologia , Doenças do Prematuro/metabolismo , Odorantes , Cobre/uso terapêutico , Humanos , Recém-Nascido , Doenças do Prematuro/tratamento farmacológico , Masculino , Metilaminas/metabolismoAssuntos
Doenças Ósseas/complicações , Surdez/complicações , Osteopetrose/complicações , Crânio , Adolescente , Criança , Feminino , Humanos , SíndromeRESUMO
Progeria or 'prematurely old' is an autosomal recessive trait that appears insidiously at or after the age of 6 months. Two affected siblings are reported showing radiologically progressive attenuation of the clavicles and terminal phalanges, widening of cranial sutures and mandibular hypoplasia. Scleroderma was also present. Out of 59 previously published cases five had scleroderma before the age of 2 years. Only three families with affected siblings have been previously recorded.