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1.
Int Arch Occup Environ Health ; 90(7): 619-628, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28429106

RESUMO

PURPOSE: Evidence of whether exposure to extremely low-frequency magnetic fields (ELF-MF) is related to central nervous system diseases is inconsistent. This study updates a previous study of the incidence of such diseases in a large cohort of Danish utility workers by almost doubling the period of follow-up. METHODS: We investigated the risks for dementia, motor neurone disease, Parkinson disease, multiple sclerosis and epilepsy among 32,006 men employed at the 99 utility companies that supplied Denmark with electricity during the period 1900-1993. Cases were identified in the Danish National Patient Registry and the cohort was followed during 1982-2010. Exposure was estimated from a job-exposure matrix based on company records of job title and area of work and cohort members were allocated to one of three categories (<0.1, 0.1-0.99 and ≥1.0 µT). RESULTS: For dementia, multiple sclerosis and epilepsy the incidence rate ratios (IRR) were close to unity, but higher for motor neurone disease [IRR 1.24, 95% confidence interval (CI) 0.86-1.79] and lower for Parkinson disease (IRR 0.81, 95% CI 0.67-0.97) among workers exposed to ≥0.1 µT compared with the Danish population. For the highest level of exposure (≥1.0 µT), IRRs of 1.44, 1.78, 1.40 and 1.34 were observed for dementia, motor neurone disease, multiple sclerosis and epilepsy, respectively. CONCLUSIONS: We observed elevated risks of dementia, motor neurone disease, multiple sclerosis and epilepsy and lower risks of Parkinson disease in relation to exposure to ELF-MF in a large cohort of utility employees.


Assuntos
Doenças do Sistema Nervoso Central/epidemiologia , Campos Eletromagnéticos , Exposição Ocupacional/estatística & dados numéricos , Adulto , Demência/epidemiologia , Dinamarca/epidemiologia , Epilepsia/epidemiologia , Humanos , Incidência , Estudos Longitudinais , Masculino , Doença dos Neurônios Motores/epidemiologia , Esclerose Múltipla/epidemiologia , Exposição Ocupacional/análise , Fatores de Risco
2.
Int J Environ Res Public Health ; 11(12): 12652-67, 2014 Dec 05.
Artigo em Inglês | MEDLINE | ID: mdl-25489999

RESUMO

The aim of this study is to investigate the relationships between road traffic noise exposure, annoyance caused by different noise sources and validated health indicators in a cohort of 1375 adults from the region of Basel, Switzerland. Road traffic noise exposure for each study participant was determined using modelling, and annoyance from various noise sources was inquired by means of a four-point Likert scale. Regression parameters from multivariable regression models for the von Zerssen score of somatic symptoms (point symptom score increase per annoyance category) showed strongest associations with annoyance from industry noise (2.36, 95% CI: 1.54, 3.17), neighbour noise (1.62, 95% CI: 1.17, 2.06) and road traffic noise (1.53, 95% CI: 1.09, 1.96). Increase in modelled noise exposure by 10 dB(A) resulted in a von Zerssen symptom score increase of 0.47 (95% CI: -0.01, 0.95) units. Subsequent structural equation modelling revealed that the association between physical noise exposure and health-related quality of life (HRQOL) is strongly mediated by annoyance and sleep disturbance. This study elucidates the complex interplay of different factors for the association between physical noise exposure and HRQOL.


Assuntos
Comorbidade , Exposição Ambiental , Ruído dos Transportes/efeitos adversos , Qualidade de Vida , Adulto , Índice de Massa Corporal , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Teóricos , Estudos Prospectivos , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/etiologia , Fatores Socioeconômicos , Inquéritos e Questionários , Suíça/epidemiologia
3.
Noise Health ; 16(71): 197-204, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25033784

RESUMO

Women sleep differently and report differently about sleep disturbances than men. However, it is unclear whether the sleep of women and men is affected differently by traffic noise exposure. We aimed to address gender specific noise effects by using objective and subjective exposure measures as well as objective and subjective outcome data. In a questionnaire survey conducted in 2008 including 733 women and 533 men from Basel, Switzerland, with follow-up 1 year later, we collected data on subjective sleep disturbances and annoyance to road traffic noise. Objective noise exposure data was obtained using validated propagation models. In a nested diary study with 119 participants, objective sleep efficiency and sleep duration was measured by means of actigraphic devices for 1551 nights. Data were analyzed using random intercept mixed-effects multilevel regression models adjusted for relevant confounding factors. Objectively measured sleep duration in highly exposed men (>55 dB) was reduced by 1.5 h (95% confidence interval [CI]: 2.3-0.8 h) compared with low exposed men (<30 dB). No noise effect on sleep duration was observed in women. The association of modeled noise exposure with self-reported sleep quality rating was also more pronounced in men (-0.8 unit, 95% CI: -1.4 to -0.2) than in women (-0.3 unit, 95% CI: -0.8 to 0.2). However, in highly annoyed women reduction in sleep quality and well-being rating tended to be stronger than in highly annoyed men. Our study provides some indications that noise exposure affects men's sleep differently than women's sleep, which may have distinct long-term health consequences.


Assuntos
Veículos Automotores , Ruído dos Transportes/efeitos adversos , Transtornos do Sono-Vigília/etiologia , Sono , Actigrafia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Análise Multinível , Ruído/efeitos adversos , Análise de Regressão , Fatores Sexuais , Transtornos do Sono-Vigília/fisiopatologia , Inquéritos e Questionários
4.
Int J Hyg Environ Health ; 217(2-3): 188-95, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23684342

RESUMO

BACKGROUND: Various epidemiological studies have found an association between noise exposure and sleep quality, but the mediating role of annoyance is unclear for this association. OBJECTIVES: To investigate the effects of both objectively modeled road traffic noise exposure as well as noise annoyance on subjective and objective sleep quality measures. METHODS: 1375 randomly selected participants from Basel, Switzerland, were enrolled in a questionnaire survey in 2008 with follow-up one year later (1122 participants). We assessed sleep quality by using a standardized sleep disturbance score, as well as the level of annoyance with road traffic noise at home. Objective sleep efficiency data was collected in a nested diary study by means of actigraphy from 119 subjects for 1551 nights. Residential nocturnal exposure to road traffic noise was modeled using validated models. Data were analyzed with random intercept mixed-effects regression models. RESULTS: In the main study, self-reported sleep quality was strongly related to noise annoyance (p for trend<0.001) but only moderately correlated with modeled noise exposure (p=0.07). In the nested diary study objectively measured sleep efficiency was not related to annoyance (p=0.25) but correlated with modeled noise exposure (p=0.02). Strikingly, noise induced decreased sleep efficiency was even more significant for study participants who were not annoyed with traffic noise (p=0.001). CONCLUSIONS: This study indicates that effects of nocturnal traffic noise on objective sleep quality are independent of perceived noise annoyance, whereas the association between self-reported sleep quality and noise is mediated by noise annoyance.


Assuntos
Atitude , Exposição Ambiental/efeitos adversos , Veículos Automotores , Ruído/efeitos adversos , Percepção , Transtornos do Sono-Vigília/etiologia , Sono , Adulto , Coleta de Dados , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Análise de Regressão , Autorrelato , Inquéritos e Questionários , Suíça
5.
Cancer Causes Control ; 25(2): 171-7, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24197706

RESUMO

PURPOSE: Epidemiological studies have found an association between exposure to extremely low-frequency magnetic fields (ELF-MF) and childhood leukemia. In 2005, a large British study showed an association between proximity of residence to high-voltage power lines and the risk of childhood leukemia. The association extended beyond distances at which the 'power line'-induced magnetic fields exceed background levels, suggesting that the association was not explained by the magnetic field, but might be due to chance, bias, or other risk factors associated with proximity to power lines. Our aim was to conduct a comparable study in an independent setting (Denmark). METHODS: We included 1,698 cases aged <15, diagnosed with leukemia during 1968-2006, from the Danish Cancer Registry and 3,396 controls randomly selected from the Danish childhood population and individually matched by gender and year of birth. We used geographical information systems to determine the distance between residence at birth and the nearest 132-400 kV overhead power line. RESULTS: Odds ratios (ORs) were 0.76 [95 % confidence interval (CI) 0.40-1.45] for children who lived 0-199 m from the nearest power line and 0.92 (95 % CI 0.67-1.25) for those who lived 200-599 m away when compared with children who lived ≥600 m away. When restricting the analysis to 220 and 400 kV overhead power lines, the OR for children who lived 200-599 m from a power line was 1.76 (95 % CI 0.82-3.77) compared to children who lived ≥600 m away. However, chance is a likely explanation for this finding as the result was not significant, numbers were small, and there were no indications of an higher risk closer to the lines since no cases were observed within 200 m of these. CONCLUSIONS: We found no higher risk of leukemia for children living 0-199 m or for children living 200-599 m of a 132-400 kV overhead power line. A slightly elevated OR for children living between 200 and 599 m of a 220-400 kV overhead power line is likely to be a chance finding.


Assuntos
Campos Eletromagnéticos , Exposição Ambiental/análise , Leucemia/epidemiologia , Adolescente , Estudos de Casos e Controles , Criança , Pré-Escolar , Dinamarca/epidemiologia , Feminino , Humanos , Leucemia/etiologia , Masculino , Características de Residência , Fatores de Risco
6.
Am J Epidemiol ; 178(2): 190-7, 2013 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-23788669

RESUMO

The International Agency for Research on Cancer has classified radiofrequency radiation as possibly carcinogenic. Previous studies have focused on intracranial tumors, although the skin receives much radiation. In a nationwide cohort study, 355,701 private mobile phone subscribers in Denmark from 1987 to 1995 were followed up through 2007. We calculated incidence rate ratios (IRRs) for melanoma, basal cell carcinoma, and squamous cell carcinoma by using Poisson regression models adjusted for age, calendar period, educational level, and income. Separate IRRs for head/neck tumors and torso/leg tumors were compared (IRR ratios) to further address potential confounders. We observed no overall increased risk for basal cell carcinoma, squamous cell carcinoma, or melanoma of the head and neck. After a follow-up period of at least 13 years, the IRRs for basal cell carcinoma and squamous cell carcinoma remained near unity. Among men, the IRR for melanoma of the head and neck was 1.20 (95% confidence interval: 0.65, 2.22) after a minimum 13-year follow-up, whereas the corresponding IRR for the torso and legs was 1.16 (95% confidence interval: 0.91, 1.47), yielding an IRR ratio of 1.04 (95% confidence interval: 0.54, 2.00). A similar risk pattern was seen among women, though it was based on smaller numbers. In this large, population-based cohort study, little evidence of an increased skin cancer risk was observed among mobile phone users.


Assuntos
Telefone Celular/estatística & dados numéricos , Campos Eletromagnéticos/efeitos adversos , Neoplasias Induzidas por Radiação/etiologia , Ondas de Rádio/efeitos adversos , Neoplasias Cutâneas/etiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma Basocelular/epidemiologia , Carcinoma Basocelular/etiologia , Carcinoma de Células Escamosas/epidemiologia , Carcinoma de Células Escamosas/etiologia , Dinamarca/epidemiologia , Feminino , Seguimentos , Humanos , Incidência , Masculino , Melanoma/epidemiologia , Melanoma/etiologia , Pessoa de Meia-Idade , Modelos Estatísticos , Neoplasias Induzidas por Radiação/epidemiologia , Distribuição de Poisson , Sistema de Registros , Análise de Regressão , Fatores de Risco , Neoplasias Cutâneas/epidemiologia
7.
Am J Epidemiol ; 177(9): 970-8, 2013 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-23572049

RESUMO

The aim of this study was to investigate the possible association between residential distance to high-voltage power lines and neurodegenerative diseases, especially Alzheimer's disease. A Swiss study previously found increased risk of Alzheimer's disease for people living within 50 m of a power line. A register-based case-control study including all patients diagnosed with neurodegenerative diseases during the years 1994-2010 was conducted among the entire adult population of Denmark. Using conditional logistic regression models, hazard ratios for ever living close to a power line in the time period 5-20 years before diagnosis were computed. The risks for developing dementia, Parkinson's disease, multiple sclerosis, and motor neuron disease were not increased in persons living within close vicinity of a power line. The risk of Alzheimer's disease was not increased for ever living within 50 m of a power line (hazard ratio = 1.04, 95% confidence interval: 0.69, 1.56). No dose-response according to number of years of living within 50 m of a power line was observed, but there were weak indications of an increased risk for persons diagnosed by the age of 75 years. Overall, there was little support for an association between neurodegenerative disease and living close to power lines.


Assuntos
Demência/epidemiologia , Campos Eletromagnéticos/efeitos adversos , Doenças Neurodegenerativas/epidemiologia , Características de Residência , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Doença de Alzheimer/epidemiologia , Doença de Alzheimer/etiologia , Estudos de Casos e Controles , Demência/etiologia , Dinamarca , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Doenças Neurodegenerativas/etiologia , Alta do Paciente/estatística & dados numéricos , Modelos de Riscos Proporcionais , Sistema de Registros , Fatores de Tempo , Adulto Jovem
8.
Bioelectromagnetics ; 34(5): 366-74, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23417714

RESUMO

A framework for the combination of near-field (NF) and far-field (FF) radio frequency electromagnetic exposure sources to the average organ and whole-body specific absorption rates (SARs) is presented. As a reference case, values based on numerically derived SARs for whole-body and individual organs and tissues are combined with realistic exposure data, which have been collected using personal exposure meters during the Swiss Qualifex study. The framework presented can be applied to any study region where exposure data is collected by appropriate measurement equipment. Based on results derived from the data for the region of Basel, Switzerland, the relative importance of NF and FF sources to the personal exposure is examined for three different study groups. The results show that a 24-h whole-body averaged exposure of a typical mobile phone user is dominated by the use of his or her own mobile phone when a Global System for Mobile Communications (GSM) 900 or GSM 1800 phone is used. If only Universal Mobile Telecommunications System (UMTS) phones are used, the user would experience a lower exposure level on average caused by the lower average output power of UMTS phones. Data presented clearly indicate the necessity of collecting band-selective exposure data in epidemiological studies related to electromagnetic fields.


Assuntos
Campos Eletromagnéticos , Exposição Ambiental , Efeitos da Radiação , Ondas de Rádio , Irradiação Corporal Total , Absorção , Adulto , Algoritmos , Estatura , Índice de Massa Corporal , Peso Corporal , Encéfalo/efeitos da radiação , Telefone Celular/classificação , Simulação por Computador , Fontes de Energia Elétrica , Estudos Epidemiológicos , Humanos , Cristalino/efeitos da radiação , Masculino , Manequins , Modelos Biológicos , Doses de Radiação , Radiometria/instrumentação , Pele/efeitos da radiação , Suíça , Interface Usuário-Computador
9.
Bioelectromagnetics ; 33(8): 682-94, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22674152

RESUMO

In five countries (Belgium, Switzerland, Slovenia, Hungary, and the Netherlands), personal radio frequency electromagnetic field measurements were performed in different microenvironments such as homes, public transports, or outdoors using the same exposure meters. From the mean personal field exposure levels (excluding mobile phone exposure), whole-body absorption values in a 1-year-old child and adult male model were calculated using a statistical multipath exposure method and compared for the five countries. All mean absorptions (maximal total absorption of 3.4 µW/kg for the child and 1.8 µW/kg for the adult) were well below the International Commission on Non-Ionizing Radiation Protection (ICNIRP) basic restriction of 0.08 W/kg for the general public. Generally, incident field exposure levels were well correlated with whole-body absorptions (SAR(wb) ), although the type of microenvironment, frequency of the signals, and dimensions of the considered phantom modify the relationship between these exposure measures. Exposure to the television and Digital Audio Broadcasting band caused relatively higher SAR(wb) values (up to 65%) for the 1-year-old child than signals at higher frequencies due to the body size-dependent absorption rates. Frequency Modulation (FM) caused relatively higher absorptions (up to 80%) in the adult male.


Assuntos
Cidades/estatística & dados numéricos , Campos Eletromagnéticos , Exposição Ambiental/análise , Ondas de Rádio , Irradiação Corporal Total , Absorção , Adulto , Carga Corporal (Radioterapia) , Meio Ambiente , Humanos , Lactente , Masculino , Imagens de Fantasmas
10.
PLoS One ; 7(5): e37455, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22624036

RESUMO

BACKGROUND: There is persistent public concern about sleep disturbances due to radiofrequency electromagnetic field (RF-EMF) exposure. The aim of this prospective cohort study was to investigate whether sleep quality is affected by mobile phone use or by other RF-EMF sources in the everyday environment. METHODS: We conducted a prospective cohort study with 955 study participants aged between 30 and 60 years. Sleep quality and daytime sleepiness was assessed by means of standardized questionnaires in May 2008 (baseline) and May 2009 (follow-up). We also asked about mobile and cordless phone use and asked study participants for consent to obtain their mobile phone connection data from the mobile phone operators. Exposure to environmental RF-EMF was computed for each study participant using a previously developed and validated prediction model. In a nested sample of 119 study participants, RF-EMF exposure was measured in the bedroom and data on sleep behavior was collected by means of actigraphy during two weeks. Data were analyzed using multivariable regression models adjusted for relevant confounders. RESULTS: In the longitudinal analyses neither operator-recorded nor self-reported mobile phone use was associated with sleep disturbances or daytime sleepiness. Also, exposure to environmental RF-EMF did not affect self-reported sleep quality. The results from the longitudinal analyses were confirmed in the nested sleep study with objectively recorded exposure and measured sleep behavior data. CONCLUSIONS: We did not find evidence for adverse effects on sleep quality from RF-EMF exposure in our everyday environment.


Assuntos
Campos Eletromagnéticos/efeitos adversos , Ondas de Rádio/efeitos adversos , Sono/efeitos da radiação , Adulto , Telefone Celular , Estudos de Coortes , Humanos , Estudos Longitudinais , Pessoa de Meia-Idade , Estudos Prospectivos , Análise de Regressão , Inquéritos e Questionários , Suíça
11.
Environ Int ; 38(1): 29-36, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21982030

RESUMO

BACKGROUND: There is public concern regarding potential health effects of radio frequency electromagnetic fields (RF-EMF) exposure, as produced by mobile phones or broadcast transmitters. The objective of this study was to investigate the association between RF-EMF exposure and non-specific symptoms and tinnitus in a prospective cohort study. METHODS: In 2008, 1375 randomly selected participants from Basel, Switzerland, were enrolled in a questionnaire survey with follow-up after one year (participation rate 82%). A score for somatic complaints (von Zerssen list) and headache (HIT-6) was assessed. Far-field environmental RF-EMF exposure was predicted using a validated prediction model. Regarding near-field exposure, self-reported mobile and cordless phone use as well as mobile phone operator data were collected. In multivariate regression models, we investigated whether exposure at baseline (cohort analysis) or changes in exposure between baseline and follow-up (change analysis) were related to changes in health scores. RESULTS: For participants in the top decile of environmental far-field RF-EMF exposure at baseline, in comparison to participants exposed below the median value, the change in the von Zerssen- and HIT-6-scores between baseline and follow-up was -0.12 (95%-CI: -1.79 to 1.56) and -0.37 (95%-CI: -1.80 to 1.07) units, respectively. Exposure to near-field sources and a change in exposure between baseline and follow-up were not related to non-specific symptoms. Similarly, no association between RF-EMF exposure and tinnitus was observed. CONCLUSIONS: In this first cohort study using objective and well-validated RF-EMF exposure measures, we did not observe an association between RF-EMF exposure and non-specific symptoms or tinnitus.


Assuntos
Campos Eletromagnéticos/efeitos adversos , Exposição Ambiental/estatística & dados numéricos , Ondas de Rádio/efeitos adversos , Zumbido/etiologia , Adulto , Telefone Celular , Feminino , Seguimentos , Cefaleia/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Estudos Prospectivos , Análise de Regressão , Inquéritos e Questionários , Suíça
12.
Bioelectromagnetics ; 33(1): 75-85, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21755521

RESUMO

Body-worn radiofrequency electromagnetic field (RF-EMF) personal exposure meters (PEMs) have been increasingly used for exposure assessment in epidemiological research. However, little research on the measurement accuracy of these devices is available. In this article a novel measurement setup and a measurement protocol are presented for characterizing and testing PEMs. The whole setup and procedure is tested using two EME SPY 120 devices. The performance of the PEM was analyzed for absolute measurements in an anechoic chamber. Modulated signals representing the different services as real signals generated by appropriate testers were used. Measurement results were evaluated with respect to a root mean square detector. We found that measurement accuracy depends strongly on the carrier frequency and also on the number of occupied time slots for Time Division Multiple Access (TDMA)-based services. Thus, correction factors can only be derived if the distribution of the network configuration over the measurement time for all measurement points is available. As a result of the simplicity of the measurement setup and the straightforward measurement protocol, the possibility of fast validation leads to a higher accuracy in the characterization and testing of PEMs.


Assuntos
Exposição Ambiental/análise , Monitoramento de Radiação/métodos , Ondas de Rádio , Telefone Celular , Humanos , Monitoramento de Radiação/instrumentação , Televisão
13.
Bioelectromagnetics ; 33(3): 187-206, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22021071

RESUMO

We conducted a systematic review of scientific studies to evaluate whether the use of wireless phones is linked to an increased incidence of the brain cancer glioma or other tumors of the head (meningioma, acoustic neuroma, and parotid gland), originating in the areas of the head that most absorb radiofrequency (RF) energy from wireless phones. Epidemiology and in vivo studies were evaluated according to an agreed protocol; quality criteria were used to evaluate the studies for narrative synthesis but not for meta-analyses or pooling of results. The epidemiology study results were heterogeneous, with sparse data on long-term use (≥ 10 years). Meta-analyses of the epidemiology studies showed no statistically significant increase in risk (defined as P < 0.05) for adult brain cancer or other head tumors from wireless phone use. Analyses of the in vivo oncogenicity, tumor promotion, and genotoxicity studies also showed no statistically significant relationship between exposure to RF fields and genotoxic damage to brain cells, or the incidence of brain cancers or other tumors of the head. Assessment of the review results using the Hill criteria did not support a causal relationship between wireless phone use and the incidence of adult cancers in the areas of the head that most absorb RF energy from the use of wireless phones. There are insufficient data to make any determinations about longer-term use (≥ 10 years).


Assuntos
Neoplasias Encefálicas/etiologia , Telefone Celular , Neoplasias Induzidas por Radiação/etiologia , Adulto , Neoplasias Encefálicas/epidemiologia , Estudos de Casos e Controles , Estudos de Coortes , Glioma/epidemiologia , Glioma/etiologia , Humanos , Neoplasias Meníngeas/epidemiologia , Neoplasias Meníngeas/etiologia , Meningioma/epidemiologia , Meningioma/etiologia , Neoplasias Induzidas por Radiação/epidemiologia , Neuroma Acústico/epidemiologia , Neuroma Acústico/etiologia , Neoplasias Parotídeas/etiologia , Ondas de Rádio/efeitos adversos , Medição de Risco , Fatores de Risco
14.
BMJ ; 343: d6387, 2011 Oct 19.
Artigo em Inglês | MEDLINE | ID: mdl-22016439

RESUMO

OBJECTIVE: To investigate the risk of tumours in the central nervous system among Danish mobile phone subscribers. DESIGN: Nationwide cohort study. SETTING: Denmark. PARTICIPANTS: All Danes aged ≥ 30 and born in Denmark after 1925, subdivided into subscribers and non-subscribers of mobile phones before 1995. MAIN OUTCOME MEASURES: Risk of tumours of the central nervous system, identified from the complete Danish Cancer Register. Sex specific incidence rate ratios estimated with log linear Poisson regression models adjusted for age, calendar period, education, and disposable income. RESULTS: 358,403 subscription holders accrued 3.8 million person years. In the follow-up period 1990-2007, there were 10,729 cases of tumours of the central nervous system. The risk of such tumours was close to unity for both men and women. When restricted to individuals with the longest mobile phone use--that is, ≥ 13 years of subscription--the incidence rate ratio was 1.03 (95% confidence interval 0.83 to 1.27) in men and 0.91 (0.41 to 2.04) in women. Among those with subscriptions of ≥ 10 years, ratios were 1.04 (0.85 to 1.26) in men and 1.04 (0.56 to 1.95) in women for glioma and 0.90 (0.57 to 1.42) in men and 0.93 (0.46 to 1.87) in women for meningioma. There was no indication of dose-response relation either by years since first subscription for a mobile phone or by anatomical location of the tumour--that is, in regions of the brain closest to where the handset is usually held to the head. CONCLUSIONS: In this update of a large nationwide cohort study of mobile phone use, there were no increased risks of tumours of the central nervous system, providing little evidence for a causal association.


Assuntos
Neoplasias Encefálicas/etiologia , Telefone Celular , Glioma/etiologia , Neoplasias Meníngeas/etiologia , Meningioma/etiologia , Adulto , Neoplasias Encefálicas/epidemiologia , Causalidade , Estudos de Coortes , Dinamarca/epidemiologia , Feminino , Glioma/epidemiologia , Humanos , Incidência , Modelos Lineares , Estudos Longitudinais , Masculino , Neoplasias Meníngeas/epidemiologia , Meningioma/epidemiologia , Distribuição de Poisson , Sistema de Registros , Risco , Fatores Socioeconômicos , Fatores de Tempo
15.
Bull World Health Organ ; 88(12): 887-896F, 2010 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-21124713

RESUMO

OBJECTIVE: to review and evaluate the recent literature on the health effects of exposure to mobile phone base station (MPBS) radiation. METHODS: we performed a systematic review of randomized human trials conducted in laboratory settings and of epidemiological studies that investigated the health effects of MPBS radiation in the everyday environment. FINDINGS: we included in the analysis 17 articles that met our basic quality criteria: 5 randomized human laboratory trials and 12 epidemiological studies. The majority of the papers (14) examined self-reported non-specific symptoms of ill-health. Most of the randomized trials did not detect any association between MPBS radiation and the development of acute symptoms during or shortly after exposure. The sporadically observed associations did not show a consistent pattern with regard to symptoms or types of exposure. We also found that the more sophisticated the exposure assessment, the less likely it was that an effect would be reported. Studies on health effects other than non-specific symptoms and studies on MPBS exposure in children were scarce. CONCLUSION: the evidence for a missing relationship between MPBS exposure up to 10 volts per metre and acute symptom development can be considered strong because it is based on randomized, blinded human laboratory trials. At present, there is insufficient data to draw firm conclusions about health effects from long-term low-level exposure typically occurring in the everyday environment.


Assuntos
Telefone Celular , Relação Dose-Resposta à Radiação , Campos Eletromagnéticos/efeitos adversos , Exposição Ambiental , Ondas de Rádio/efeitos adversos , Adulto , Criança , Estudos Epidemiológicos , Feminino , Humanos , Masculino , Ensaios Clínicos Controlados Aleatórios como Assunto
17.
Radiat Res ; 174(3): 347-56, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20726726

RESUMO

The aim of this cross-sectional study was to investigate the association between exposure to various sources of radiofrequency electromagnetic fields (RF EMFs) in the everyday environment and sleep quality, which is a common public health concern. We assessed self-reported sleep disturbances and daytime sleepiness in a random population sample of 1,375 inhabitants from the area of Basel, Switzerland. Exposure to environmental far-field RF EMFs was predicted for each individual using a prediction model that had been developed and validated previously. Self-reported cordless and mobile phone use as well as objective mobile phone operator data for the previous 6 months were also considered in the analyses. In multivariable regression models, adjusted for relevant confounders, no associations between environmental far-field RF EMF exposure and sleep disturbances or excessive daytime sleepiness were observed. The 10% most exposed participants had an estimated risk for sleep disturbances of 1.11 (95% CI: 0.50 to 2.44) and for excessive daytime sleepiness of 0.58 (95% CI: 0.31 to 1.05). Neither mobile phone use nor cordless phone use was associated with decreased sleep quality. The results of this large cross-sectional study did not indicate an impairment of subjective sleep quality due to exposure from various sources of RF EMFs in everyday life.


Assuntos
Campos Eletromagnéticos , Ondas de Rádio , Sono , Adulto , Estudos Transversais , Exposição Ambiental , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários
18.
Environ Res ; 110(7): 658-63, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20638656

RESUMO

BACKGROUND: Only limited data are available on personal radio frequency electromagnetic field (RF-EMF) exposure in everyday life. Several European countries performed measurement studies in this area of research. However, a comparison between countries regarding typical exposure levels is lacking. OBJECTIVES: To compare for the first time mean exposure levels and contributions of different sources in specific environments between different European countries. METHODS: In five countries (Belgium, Switzerland, Slovenia, Hungary, and the Netherlands), measurement studies were performed using the same personal exposure meters. The pooled data were analyzed using the robust regression on order statistics (ROS) method in order to allow for data below the detection limit. Mean exposure levels were compared between different microenvironments such as homes, public transports, or outdoor. RESULTS: Exposure levels were of the same order of magnitude in all countries and well below the international exposure limits. In all countries except for the Netherlands, the highest total exposure was measured in transport vehicles (trains, car, and busses), mainly due to radiation from mobile phone handsets (up to 97%). Exposure levels were in general lower in private houses or flats than in offices and outdoors. At home, contributions from various sources were quite different between countries. CONCLUSIONS: Highest total personal RF-EMF exposure was measured inside transport vehicles and was well below international exposure limits. This is mainly due to mobile phone handsets. Mobile telecommunication can be considered to be the main contribution to total RF-EMF exposure in all microenvironments.


Assuntos
Campos Eletromagnéticos , Exposição Ambiental , Ondas de Rádio , População Urbana , Europa (Continente) , Humanos
19.
Environ Int ; 36(7): 714-20, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20538340

RESUMO

The use of personal exposure meters (exposimeters) has been recommended for measuring personal exposure to radio frequency electromagnetic fields (RF-EMF) from environmental far-field sources in everyday life. However, it is unclear to what extent exposimeter readings are affected by measurements taken when personal mobile and cordless phones are used. In addition, the use of exposimeters in large epidemiological studies is limited due to high costs and large effort for study participants. In the current analysis we aimed to investigate the impact of personal phone use on exposimeter readings and to evaluate different exposure assessment methods potentially useful in epidemiological studies. We collected personal exposimeter measurements during one week and diary data from 166 study participants. Moreover, we collected spot measurements in the participants' bedrooms and data on self-estimated exposure, assessed residential exposure to fixed site transmitters by calculating the geo-coded distance and mean RF-EMF from a geospatial propagation model, and developed an exposure prediction model based on the propagation model and exposure relevant behavior. The mean personal exposure was 0.13 mW/m(2), when measurements during personal phone calls were excluded and 0.15 mW/m(2), when such measurements were included. The Spearman correlation with personal exposure (without personal phone calls) was 0.42 (95%-CI: 0.29 to 0.55) for the spot measurements, -0.03 (95%-CI: -0.18 to 0.12) for the geo-coded distance, 0.28 (95%-CI: 0.14 to 0.42) for the geospatial propagation model, 0.50 (95%-CI: 0.37 to 0.61) for the full exposure prediction model and 0.06 (95%-CI: -0.10 to 0.21) for self-estimated exposure. In conclusion, personal exposure measured with exposimeters correlated best with the full exposure prediction model and spot measurements. Self-estimated exposure and geo-coded distance turned out to be poor surrogates for personal exposure.


Assuntos
Campos Eletromagnéticos , Exposição Ambiental/análise , Monitoramento Ambiental/métodos , Estudos Epidemiológicos , Ondas de Rádio , Adolescente , Adulto , Telefone Celular/estatística & dados numéricos , Exposição Ambiental/estatística & dados numéricos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
20.
Environ Health ; 9: 23, 2010 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-20487532

RESUMO

BACKGROUND: The development of new wireless communication technologies that emit radio frequency electromagnetic fields (RF-EMF) is ongoing, but little is known about the RF-EMF exposure distribution in the general population. Previous attempts to measure personal exposure to RF-EMF have used different measurement protocols and analysis methods making comparisons between exposure situations across different study populations very difficult. As a result, observed differences in exposure levels between study populations may not reflect real exposure differences but may be in part, or wholly due to methodological differences. METHODS: The aim of this paper is to develop a study protocol for future personal RF-EMF exposure studies based on experience drawn from previous research. Using the current knowledge base, we propose procedures for the measurement of personal exposure to RF-EMF, data collection, data management and analysis, and methods for the selection and instruction of study participants. RESULTS: We have identified two basic types of personal RF-EMF measurement studies: population surveys and microenvironmental measurements. In the case of a population survey, the unit of observation is the individual and a randomly selected representative sample of the population is needed to obtain reliable results. For microenvironmental measurements, study participants are selected in order to represent typical behaviours in different microenvironments. These two study types require different methods and procedures. CONCLUSION: Applying our proposed common core procedures in future personal measurement studies will allow direct comparisons of personal RF-EMF exposures in different populations and study areas.


Assuntos
Exposição Ambiental , Ondas de Rádio , Exposição Ambiental/efeitos adversos , Sistemas de Informação Geográfica , Humanos , Prontuários Médicos , Seleção de Pacientes , Radiação , Ondas de Rádio/efeitos adversos , Projetos de Pesquisa , Estatística como Assunto , Inquéritos e Questionários
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