RESUMO
Livedoid vasculopathy is a rare condition which predominantly affects young women. It is characterized by intense painful purpuric maculae in the legs, ankles and feet, due to thrombosis of the small and medium-sized dermal vessels, in the absence of vasculitis. Livedoid vasculopathy has been frequently associated with hypercoagulable states and antiphospholipid syndrome. We describe a 34-year-old White woman suffering from systemic lupus erythematosus, livedo reticularis, haemolytic anaemia, severe thrombocytopenia and recurrent venous thrombosis who was admitted to the hospital for extremely painful purpuric lesions in her lower limbs. The clinical and histological findings were diagnostic of livedoid vasculopathy. Once the initial sub-therapeutic international normalized ratio levels were corrected, livedoid vasculopathy did not recur. Tests for antiphospholipid antibodies were repeatedly negative. This case, the first reported of livedoid vasculopathy in a patient with seronegative antiphospholipid syndrome and systemic lupus erythematosus, draws attention to livedoid vasculopathy, a thrombotic dermopathy that may be under-diagnosed in patients with antiphospholipid syndrome.
Assuntos
Síndrome Antifosfolipídica , Livedo Reticular/etiologia , Lúpus Eritematoso Sistêmico/complicações , Trombose , Adulto , Anticorpos Antifosfolipídeos/sangue , Síndrome Antifosfolipídica/sangue , Síndrome Antifosfolipídica/imunologia , Feminino , Humanos , Livedo Reticular/patologia , Lúpus Eritematoso Sistêmico/fisiopatologia , Recidiva , Trombose/etiologia , Trombose/prevenção & controleRESUMO
We report one case of salmonellosis aortitis in a 70 years old man after an episode of gastroenteritis due to Salmonella enteritidis successfully resolved with extraanatomic by-pass and prolonged antibiotic administration.
Assuntos
Aortite/etiologia , Infecções por Salmonella/complicações , Salmonella enteritidis , Idoso , Anti-Infecciosos/uso terapêutico , Aneurisma da Aorta Abdominal/complicações , Aneurisma da Aorta Abdominal/diagnóstico por imagem , Aneurisma da Aorta Abdominal/cirurgia , Aortite/complicações , Aortite/cirurgia , Prótese Vascular , Ciprofloxacina/uso terapêutico , Seguimentos , Humanos , Masculino , Infecções por Salmonella/tratamento farmacológico , Fatores de Tempo , Tomografia Computadorizada por Raios XRESUMO
Presentamos un caso de aortitis salmonelósica en un varón de 70 años tras un episodio de gastroenteritis aguda por Salmonella enteritidis que fue tratado con éxito mediante by-pass extraanatómico y administración prolongada de ciprofloxacino (AU)