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1.
Comput Methods Biomech Biomed Engin ; 24(3): 320-332, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33063557

RESUMO

In total knee arthroplasty (TKA), force is transmitted into the tibia by a combined plate-stem device along with cemented or cementless stem fixation. The present work analyzes this force transmission in finite element simulations with the main aim to avoid reported postsurgical bone density reduction as a consequence of a reduced tibial bone loading. In the numerical analysis different implant materials, stem/extension lengths and implant-to-stem interface conditions are considered, from a stiff fully cemented fixation to sliding contact conditions with a low friction coefficient. The impact of these variations on bone loading changes are measured by (i) decomposing the total force into parts mediated by the plate and by the stem and by (ii) post-surgery strain energy density (SED) deviations. Based on a bionics-inspired perspective on how nature in pre-operative conditions carries out force transfer from the knee joint into the tibia, a modified implant-bone interface is suggested that alters force transmission towards physiological conditions while preserving the geometries of the standard plate-stem endoprosthesis design. The key aspect is that the axial force is predominantly transmitted through the plate into proximal bone which requires a compliant bone-stem interface as realized by sliding friction conditions at a low friction coefficient. These interface conditions avoid stress shielding almost completely, preserve pre-surgery bone loading such that bone resorption is not likely to occur.


Assuntos
Artroplastia do Joelho , Prótese do Joelho , Metais/química , Reoperação , Estresse Mecânico , Tíbia/cirurgia , Feminino , Análise de Elementos Finitos , Humanos , Pessoa de Meia-Idade , Desenho de Prótese , Suporte de Carga
2.
Eur J Vasc Endovasc Surg ; 51(2): 187-93, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26391962

RESUMO

OBJECTIVE/BACKGROUND: Ultrasound measurement of aortic diameter for aneurysm screening allows supervision of aneurysm growth. Additional biomechanical analysis of wall motion and aneurysm deformation can supply information about individual elastic properties and the pathological state of the aortic wall. Local aortic wall motion was analyzed through imaged aortic segments according to age and pathology. METHODS: Sixty-five patients were examined with a commercial four dimensional ultrasound system (4D-US). Three groups were defined: patients with normal aortic diameter and younger than 60 years of age (n = 21); those with normal aortic diameter and older than 60 years of age (n = 25); and those with infrarenal aortic aneurysm (n = 19). A diastolic reference shape of aortic wall segments was obtained and local and temporally resolved wall strain was determined. Indices characterizing the resulting wall strain distribution were determined. RESULTS: The analysis of biomechanical properties displayed increasing heterogeneous and dyssynchronous circumferential strain with increasing patient age. Young patients exhibited higher mean strain amplitude. The distribution of the spatial heterogeneity index and local strain ratio was inversely proportional to age. The maximum local strain amplitude was significantly higher in the young (0.26 ± 0.17) compared with the old (0.16 ± 0.07) or aneurysmal aorta (0.16 ± 0.10). Temporal dyssynchrony significantly differed between young (0.13 ± 0.10) and old (aneurysmal 0.31 ± 0.04, non-aneurysmal 0.29 ± 0.05), regardless of aortic diameter. The spatial heterogeneity index and local strain ratio differentiate non-aneurysmal and aneurysmal aorta, regardless of age. CONCLUSIONS: 4D-US strain imaging enables description of individual wall motion (kinematics) of the infrarenal aorta with high spatial and temporal resolution. Functional differences between young, old, and aneurysmal aorta can be described by mean (circumferential) strain amplitude, the spatial heterogeneity index, and the local strain ratio. Further investigation is required to refine this new perspective of patient individualized characterization of the pathological AAA wall and eventually to rupture risk stratification.


Assuntos
Aorta Abdominal/diagnóstico por imagem , Aneurisma da Aorta Abdominal/diagnóstico por imagem , Processamento de Imagem Assistida por Computador , Imageamento Tridimensional , Fatores Etários , Algoritmos , Aorta Abdominal/fisiopatologia , Aneurisma da Aorta Abdominal/complicações , Aneurisma da Aorta Abdominal/fisiopatologia , Ruptura Aórtica/etiologia , Fenômenos Biomecânicos , Estudos de Casos e Controles , Humanos , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Fluxo Sanguíneo Regional , Medição de Risco , Fatores de Risco , Estresse Mecânico , Ultrassonografia
3.
J Microsc ; 213(3): 313-20, 2004 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15009699

RESUMO

Up to 90% of the fatigue life of engineering alloys results from the initiation and propagation of microstructurally short cracks. Owing to their strong interactions with microstructural features, e.g. grain and phase boundaries, they exhibit substantially non-uniform propagation kinetics as compared with the growth rate of long cracks, which can be well described using a power-law function of the range of the stress-intensity factor DeltaK. In the present paper interactions between the crystallographic misorientation of grain and phase boundaries and microcracks in an austenitic/ferritic stainless steel are discussed and quantified by means of fatigue experiments in combination with the electron backscattered diffraction technique. In the second part a numerical model for the simulation of microcracks is introduced, which is capable of taking real microstructural arrangements into consideration.


Assuntos
Análise de Falha de Equipamento/métodos , Microscopia Eletrônica , Aço/análise , Estresse Mecânico
4.
J Cataract Refract Surg ; 26(2): 282-6, 2000 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-10683799

RESUMO

PURPOSE: To study the propagation of ultrasonic shock waves in viscoelastic agents and the resulting corneal load. SETTING: University Siegen, Institute for Mechanics and Control Engineering, Siegen, Germany. METHODS: The anterior chamber of a manufactured artificial eye was constructed according to anatomic dimensions. Three openings were drilled--for the phaco tip, for the exchange of a viscoelastic agent or water, and for the shock-wave sensor. The sensor was fixed to the area corresponding to the corneal apex. The sensor signal was analyzed using a direct oscilloscope that measured the amplitude reaching the corneal apex. Shock-wave propagation in several viscoelastic agents was compared with that in balanced salt solution. RESULTS: In hydroxypropyl methylcellulose, the shock wave was amplified or influenced slightly. In hyaluronic-acid preparations, acoustic dampening occurred. CONCLUSION: Removal of hyaluronic-acid derivatives prior to phacoemulsification is not necessary.


Assuntos
Câmara Anterior/diagnóstico por imagem , Sulfatos de Condroitina/química , Ácido Hialurônico/química , Metilcelulose/análogos & derivados , Modelos Anatômicos , Facoemulsificação , Ultrassom , Temperatura Corporal , Humanos , Derivados da Hipromelose , Injeções , Metilcelulose/química , Ultrassonografia
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