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Clin Microbiol Infect ; 23(10): 776.e1-776.e5, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28412383

RESUMO

OBJECTIVES: A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections. METHODS: A total of 370 cases from 21 countries were evaluated. RESULTS: The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L). CONCLUSIONS: Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.


Assuntos
Aspergilose/epidemiologia , Aspergilose/microbiologia , Aspergillus/classificação , Aspergillus/isolamento & purificação , Anfotericina B/farmacologia , Antifúngicos/farmacologia , Aspergillus/efeitos dos fármacos , Monitoramento Epidemiológico , Europa (Continente)/epidemiologia , Humanos , Testes de Sensibilidade Microbiana , Prevalência , Estudos Prospectivos
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