Improving Crowdsourcing-Based Image Classification Through Expanded Input Elicitation and Machine Learning.

This work investigates how different forms of input elicitation obtained from crowdsourcing can be utilized to improve the quality of inferred labels for image classification tasks, where an image must be labeled as either positive or negative depending on the presence/absence of a specified object. Five types of input elicitation methods are tested: binary classification (positive or negative); the (x, y)-coordinate of the position participants believe a target object is located; level of confidence in binary response (on a scale from 0 to 100%); what participants believe the majority of the other participants' binary classification is; and participant's perceived difficulty level of the task (on a discrete scale). We design two crowdsourcing studies to test the performance of a variety of input elicitation methods and utilize data from over 300 participants. Various existing voting and machine learning (ML) methods are applied to make the best use of these inputs. In an effort to assess their performance on classification tasks of varying difficulty, a systematic synthetic image generation process is developed. Each generated image combines items from the MPEG-7 Core Experiment CE-Shape-1 Test Set into a single image using multiple parameters (e.g., density, transparency, etc.) and may or may not contain a target object. The difficulty of these images is validated by the performance of an automated image classification method. Experiment results suggest that more accurate results can be achieved with smaller training datasets when both the crowdsourced binary classification labels and the average of the self-reported confidence values in these labels are used as features for the ML classifiers. Moreover, when a relatively larger properly annotated dataset is available, in some cases augmenting these ML algorithms with the results (i.e., probability of outcome) from an automated classifier can achieve even higher performance than what can be obtained by using any one of the individual classifiers. Lastly, supplementary analysis of the collected data demonstrates that other performance metrics of interest, namely reduced false-negative rates, can be prioritized through special modifications of the proposed aggregation methods.

Computer Vision Evidence Supporting Craniometric Alignment of Rat Brain Atlases to Streamline Expert-Guided, First-Order Migration of Hypothalamic Spatial Datasets Related to Behavioral Control.

The rat has arguably the most widely studied brain among all animals, with numerous reference atlases for rat brain having been published since 1946. For example, many neuroscientists have used the atlases of Paxinos and Watson (PW, first published in 1982) or Swanson (S, first published in 1992) as guides to probe or map specific rat brain structures and their connections. Despite nearly three decades of contemporaneous publication, no independent attempt has been made to establish a basic framework that allows data mapped in PW to be placed in register with S, or vice versa. Such data migration would allow scientists to accurately contextualize neuroanatomical data mapped exclusively in only one atlas with data mapped in the other. Here, we provide a tool that allows levels from any of the seven published editions of atlases comprising three distinct PW reference spaces to be aligned to atlas levels from any of the four published editions representing S reference space. This alignment is based on registration of the anteroposterior stereotaxic coordinate (z) measured from the skull landmark, Bregma (ß). Atlas level alignments performed along the z axis using one-dimensional Cleveland dot plots were in general agreement with alignments obtained independently using a custom-made computer vision application that utilized the scale-invariant feature transform (SIFT) and Random Sample Consensus (RANSAC) operation to compare regions of interest in photomicrographs of Nissl-stained tissue sections from the PW and S reference spaces. We show that z-aligned point source data (unpublished hypothalamic microinjection sites) can be migrated from PW to S space to a first-order approximation in the mediolateral and dorsoventral dimensions using anisotropic scaling of the vector-formatted atlas templates, together with expert-guided relocation of obvious outliers in the migrated datasets. The migrated data can be contextualized with other datasets mapped in S space, including neuronal cell bodies, axons, and chemoarchitecture; to generate data-constrained hypotheses difficult to formulate otherwise. The alignment strategies provided in this study constitute a basic starting point for first-order, user-guided data migration between PW and S reference spaces along three dimensions that is potentially extensible to other spatial reference systems for the rat brain.

Automatic classification of pathological gait patterns using ground reaction forces and machine learning algorithms.

An automated gait classification method is developed in this study, which can be applied to analysis and to classify pathological gait patterns using 3D ground reaction force (GRFs) data. The study involved the discrimination of gait patterns of healthy, cerebral palsy (CP) and multiple sclerosis subjects. The acquired 3D GRFs data were categorized into three groups. Two different algorithms were used to extract the gait features; the GRFs parameters and the discrete wavelet transform (DWT), respectively. Nearest neighbor classifier (NNC) and artificial neural networks (ANN) were also investigated for the classification of gait features in this study. Furthermore, different feature sets were formed using a combination of the 3D GRFs components (mediolateral, anterioposterior, and vertical) and their various impacts on the acquired results were evaluated. The best leave-one-out (LOO) classification accuracy 85% was achieved. The results showed some improvement through the application of a features selection algorithm based on M-shaped value of vertical force and the statistical test ANOVA of mediolateral and anterioposterior forces. The optimal feature set of six features enhanced the accuracy to 95%. This work can provide an automated gait classification tool that may be useful to the clinician in the diagnosis and identification of pathological gait impairments.

Obtaining the phase of an interferogram by use of an evolution strategy: part I.

We present a method for obtaining the phase of a noisy simulated interferogram. We find the wave-front aberrations by transforming the problem of fitting a polynomial into an optimization problem, which is then solved using an evolutionary algorithm. Our experimental results show that our method yields a more accurate solution than other methods commonly used to solve this problem.