[Experimental study of the effect of the association of hyperthermia and BCNU on solid sarcoma 180 in C3H mice. Development of tumor volume, survival and rate of cure]. / Estudio experimental de la asociación de hipertermia y BCNU sobre el sarcoma 180 sólido en el ratón C3H. Evolución del volumen tumoral, supervivencia y tasa de curaciones.

The authors describe the experimental results of administering BCNU combined with hyperthermia upon the growth of sarcoma 180 of the mouse. Best results were obtained employing the combined therapy than using BCNU or hyperthermia alone, and hyperthermia was necessary in all cases where a curative effect was attained.

[Evolution of weight and survival of C3H mice with solid, subcutaneous sarcoma 180, treated with radiotherapy, hyperthermia and a combination of hyperthermia and radiotherapy]. / Evolución del peso y supervivencia de los ratones C3H con sarcoma 180sólido subcutáneo, tratados con radioterapia, hipertermia y la asociación de hipertermia más radioterapia.

The authors make an experimental study of the weight evolution and survival rate of sarcoma 180-bearing C3H mice treated by combinations of radiotherapy and hyperthermia. The body weight increased progressively in control animals. The weight increase was less marked under the effect of radiotherapy, hyperthermia, and radiotherapy plus hyperthermia, in decreasing order. While tumor-bearing control animals died after an average of 26.6 days, 3.33, 16.67 and 76.67 per cent of the mice treated respectively by radiotherapy, hyperthermia, and radiotherapy plus hyperthermia were living after 90 days.