Articular cartilage damage in the patellofemoral compartment at ACL reconstruction predicts poor postoperative subjective outcomes in patients age 40 and older.

The purpose of this study was to investigate factors that influence clinical outcomes after ACL reconstruction in patients age 40 and older. We studied 264 patients aged 40 or older and 154 patients aged 20 or younger who underwent ACL reconstruction at several surgical centers. Logistic regression analysis was conducted to identify factors that influenced the KOOS scores at 1 year post ACL reconstruction. In the older patient group, cartilage damage in the patellofemoral compartment at surgery was a significant risk factor for poor postoperative KOOS subscores (pain, ADL, sports, and QOL). Articular cartilage damage in the lateral compartment also significantly influenced one of the postoperative KOOS subscores (symptoms). In the younger patient group, articular cartilage damage in any compartments did not influenced the postoperative KOOS subscores; only two preoperative KOOS subscores (symptoms and QOL) significantly influenced their postoperative KOOS subscores. We concluded that the articular cartilage damage in the patellofemoral compartment at ACL reconstruction predicts poor KOOS subscores at one year follow-up in patients age 40 or older.

Intraoperative Kinematics in Posterior Cruciate Ligament Retaining Total Knee Arthroplasty Using Different Inserts.

We analyzed the intraoperative kinematics of total knee arthroplasty (TKA) using a navigation system to investigate the influence of different inserts on kinematics. This was a retrospective observational study. The Vanguard individualized design (33 patients, 33 knees) XP and anterior-stabilized (AS) inserts were used in TKA for osteoarthritis. Kinematic data were intraoperatively recorded. The range of motion, tibiofemoral rotational angle, anteroposterior translation of the femur, and varus-valgus laxity were compared between the two inserts (XP vs. AS). There was no significant difference in the range of motion (extension: XP, 3.7° ± 3.3° vs. AS, 3.8° ± 3.3°, p = 0.84; flexion: XP, 138.1° ± 10.2° vs. AS, 139.0° ± 13.3°, p = 0.73). With the AS insert, the tibia was gradually internally rotated as the knee was flexed. At maximum extension, the internal rotation was smallest with AS (XP 6.5° ± 4.0° vs. AS 5.1° ± 3.4°, p = 0.022), which was also associated with smaller anterior femoral translation (maximum extension: XP, 14.1 ± 4.8 mm vs. AS, 11.3 ± 4.7 mm, p = 0.00036; 30°: XP, 23.7 ± 5.6 mm vs. AS, 20.7 ± 5.1 mm, p = 0.000033; 45°: XP, 24.4 ± 4.9 mm vs. AS, 23.2 ± 4.5 mm, p = 0.0038). The AS was associated with a lower varus-valgus laxity (30° XP 4.1° ± 3.4 vs. AS 3.3° ± 2.7°, p = 0.036; 60°: XP, 3.2° ± 3.0° vs. AS, 2.4° ± 3.3°, p = 0.0089). The AS insert facilitated sequential tibiofemoral rotation with varus-valgus stability in mid-flexion without restricting the range of motion.

A larger side-to-side difference in anterior knee laxity increases the prevalence of medial and lateral meniscal injuries in patients with ACL injuries.

PURPOSE: The objective of this study was to investigate factors that influence the prevalence of medial and lateral meniscal injuries at the time of anterior cruciate ligament (ACL) reconstruction in patients with ACL injuries. METHODS: Patients with ACL injuries at 9 institutions were enrolled in this multicentre study. Age, sex, duration between injury and surgery, pivot shift test grade, anterior knee laxity determined using the Kneelax 3 arthrometer, and other variables were assessed by logistic regression analysis. Meniscal conditions were evaluated via arthroscopy. RESULTS: In all, 830 patients were enrolled. The prevalence of medial and lateral meniscal tears was 32.0% (266 knees) and 26.5% (220 knees), respectively. Significant factors that influenced the prevalence of medial meniscal injuries were age [odds ratio (OR) 1.03; P = 0.000], side-to-side differences in instrumented anterior knee laxity before surgery (OR 1.12; P = 0.002), duration between injury and surgery (≥ 12 months) (OR 1.86; P = 0.023), and pivot shift test grade (OR 1.36; P = 0.014). Significant factors of lateral meniscal injury were side-to-side differences in anterior knee laxity before surgery (OR 1.12; P = 0.003) and the male sex (OR 1.50; P = 0.027). CONCLUSION: Greater anterior knee laxity, age, a longer duration between injury and surgery, and a higher pivot shift test grade predicted medial meniscal injury. Greater anterior knee laxity and the male sex predicted lateral meniscal injury. In patients with ACL injuries, the importance of side-to-side differences in anterior knee laxity should be rediscovered from the viewpoint of meniscal conditions. LEVEL OF EVIDENCE: Level III.

Technical Considerations and Accuracy Improvement of Accelerometer-Based Portable Computer Navigation for Performing Distal Femoral Resection in Total Knee Arthroplasty.

BACKGROUND: Accelerometer-based computer navigation has been shown to be highly accurate for performing distal femoral and proximal tibial component alignment in total knee arthroplasty (TKA), although the procedure for the femoral component is less accurate than for the tibial component. METHODS: First, 30 knees without hip osteoarthritis or proximal femoral surgeries were selected. Sequential hip adduction, abduction, and flexion were performed, and the femoral head was monitored fluoroscopically in the coronal plane before TKA. Significantly more movement was detected during hip adduction than during abduction and flexion. Then, postoperative femoral and tibial component alignment was retrospectively evaluated in 48 TKAs before fluoroscopic monitoring (early group) and in the next 61 TKAs with femoral registration using smaller adduction movements to avoid large femoral head movements (later group). Another 47 TKAs treated with the conventional intramedullary method for the distal femoral component and the extramedullary method for the proximal tibial component were also analyzed (IM and EM group) for historic control. RESULTS: Significantly large variances in the femoral component implantation of the early group were detected in both the coronal and sagittal planes. The sagittal femoral implantation angle of the early group (4.6 ± 3.0°) was significantly larger than that of the later group (3.2 ± 1.8°) when 3.5° was the target for both groups. No significant difference was detected in the variances of either the coronal or sagittal tibial component implantation, although the coronal tibial implantation angle was significantly smaller (-1.3 ± 1.3°valgus) in the early group than in the other groups. CONCLUSION: Accelerometer-based navigation sometimes has technical issues during registration associated with hip adduction. We showed that femoral registration without large adduction movements will enable more accurate femoral implantation. Surgeons should also keep in mind that the coronal tibial component is likely to be in valgus alignment (about 1°) even if a neutral angle (0°) is selected with this particular device.

Intra-operative gaps affect outcome and postoperative kinematics in vivo following cruciate-retaining total knee arthroplasty.

PURPOSE: The following investigation evaluates the effect of intra-operative gaps after posterior cruciate ligament-retaining total knee arthroplasty using two-dimensional/three-dimensional registration and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). METHODS: Patients were divided into two groups according to their 90°-0° component gap changes using a device designed by our laboratory. The wide gap group was defined as more than 3 mm (4.3 ± 0.7 mm), and the narrow gap group was defined as less than 3 mm (1.3 ± 1.3 mm). RESULTS: Under non-WB (weight bearing) conditions, the wide flexion gap group (N = 10) showed a significant anterior displacement of the medial femoral condyle as compared with the narrow flexion gap group (N = 20). Despite no significant differences observed under WB conditions, both femoral condyle positions during flexion were significantly more posterior than during extension. WOMAC of the tight gap group showed worse scores for two functional items demanding knee flexion (bending to floor and getting on/off toilet). CONCLUSION: The large flexion gap could influence the late rollback under non-WB conditions and better WOMAC functional scores in the flexion items. Three to four millimetre laxity at 90°-0° component gaps may be adequate and might be necessary to carry out daily life activities.

Different femorotibial contact on the weight-bearing: midflexion between normal and varus aligned knees after total knee arthroplasty.

PURPOSE: The influence of residual malalignment on biomechanical analysis after total knee arthroplasty (TKA) is currently uncertain. The hypothesis is that postoperative alignment would influence the in vivo kinematics after TKA, under weight-bearing conditions but not under non-weight-bearing condition. The purpose of the present study was to compare weight-bearing and non-weight-bearing conditions and to evaluate the effect of the postoperative alignment on the in vivo kinematics after posterior cruciate ligament-retaining TKA during midflexion using 2-dimensional/3-dimensional registration. METHODS: Thirty knees of 30 patients with pre-operative varus deformity were divided into 2 groups according to their postoperative alignment: the normal alignment group (N = 21) and the varus alignment group (N = 9). RESULTS: Under weight-bearing conditions, the varus alignment group showed a significant posterior displacement of the medial femoral condyle (flexion: 80°, 90° P < 0.05) and a significant anterior displacement of the lateral femoral condyle (flexion: 10° P < 0.01, 20° P < 0.05, and extension: 10°, 20° P < 0.01, 30°, 40° P < 0.05) as compared with the normal alignment group. In contrast, no significant difference in the medial and lateral femoral condyle positions under non-weight-bearing conditions was observed between the normal and varus alignment groups. CONCLUSION: The postoperative alignment influenced knee kinematics under weight-bearing conditions. The weight load influenced knee kinematics through posterior tibial slope and induced greater lateral femoral condyle mobility, which might explain the better clinical and functional outcome. These findings contribute to gaining a proper understanding of the in vivo kinematics of the postoperative varus alignment and might be useful for orthopaedic surgeons in the achievement of patient satisfaction. LEVEL OF EVIDENCE: III.

Significant effect of the posterior tibial slope on the weight-bearing, midflexion in vivo kinematics after cruciate-retaining total knee arthroplasty.

The purpose of the present study was to compare weight bearing (WB) and non-WB conditions, and to evaluate the effect of the posterior tibial slope (PTS) on the in vivo kinematics of 21 knees after posterior cruciate ligament-retaining total knee arthroplasty during midflexion using 2-dimensional/3-dimensional registration. During WB, medial pivot and bicondylar rollback were observed. During non-WB, both the medial and lateral condyles moved significantly more anteriorly as compared to the WB state. These patients were divided into 2 groups according to their PTS. The large PTS group showed a significant posterior displacement of the medial femoral condyle as compared with the small PTS group, but no significant difference was observed at the lateral femoral condyle during both WB and non-WB. The PTS influenced knee kinematics through gravity (124/125).

Significant effect of the posterior tibial slope and medial/lateral ligament balance on knee flexion in total knee arthroplasty.

PURPOSE: The intra-operative femorotibial joint gap and ligament balance, the predictors affecting these gaps and their balances, as well as the postoperative knee flexion, were examined. These factors were assessed radiographically after a posterior cruciate-retaining total knee arthroplasty (TKA). The posterior condylar offset and posterior tibial slope have been reported as the most important intra-operative factors affecting cruciate-retaining-type TKAs. The joint gap and balance have not been investigated in assessments of the posterior condylar offset and the posterior tibial slope. METHODS: The femorotibial gap and medial/lateral ligament balance were measured with an offset-type tensor. The femorotibial gaps were measured at 0°, 45°, 90° and 135° of knee flexion, and various gap changes were calculated at 0°-90° and 0°-135°. Cruciate-retaining-type arthroplasties were performed in 98 knees with varus osteoarthritis. RESULTS: The 0°-90° femorotibial gap change was strongly affected by the posterior condylar offset value (postoperative posterior condylar offset subtracted by the preoperative posterior condylar offset). The 0°-135° femorotibial gap change was significantly correlated with the posterior tibial slope and the 135° medial/lateral ligament balance. The postoperative flexion angle was positively correlated with the preoperative flexion angle, γ angle and the posterior tibial slope. Multiple-regression analysis demonstrated that the preoperative flexion angle, γ angle, posterior tibial slope and 90° medial/lateral ligament balance were significant independent factors for the postoperative knee flexion angle. The flexion angle change (postoperative flexion angle subtracted by the preoperative flexion angle) was also strongly correlated with the preoperative flexion angle, posterior tibial slope and 90° medial/lateral ligament balance. CONCLUSION: The postoperative flexion angle is affected by multiple factors, especially in cruciate-retaining-type TKAs. However, it is important to pay attention not only to the posterior tibial slope, but also to the flexion medial/lateral ligament balance during surgery. A cruciate-retaining-type TKA has the potential to achieve both stability and a wide range of motion and to improve the patients' activities of daily living.

Mucoid degeneration of the posterior cruciate ligament: a case report.

We report a case of mucoid degeneration of the posterior cruciate ligament (PCL). A 37-year-old male had suffered from right knee pain for several years. The active range of motion of his right knee was -30 extension and 100 flexion, with terminal pain. Magnetic resonance imaging (MRI) showed low proton density and T2WI with fat saturation-high signals in the PCL. Arthroscopic resection of the PCL was carried out, with immediate relief of his symptoms. This was a very rare case of mucoid degeneration of the PCL in a young healthy man. If this disease is considered preoperatively, it can be diagnosed based on characteristic MRI findings.

Anterior cruciate ligament graft impingement against the posterior cruciate ligament: diagnosis using MRI plus three-dimensional reconstruction software.

OBJECTIVE: The purpose of this study was to evaluate anterior cruciate ligament (ACL) impingement against the posterior cruciate ligament (PCL) with the knee in an extended position, which arthroscopy cannot detect. MATERIALS AND METHODS: Ten normal knees and 30 ACL-reconstructed knees were assessed using MR imaging. The three-dimensional reconstruction of the ACL, PCL, femur and tibia were carried out using commercially available three-dimensional reconstruction software. Anterior cruciate ligament impingement against the PCL was graded into three categories: Grade 1, some space between the ligaments; Grade 2, no space between the ligaments, and the reconstructed ACL ran straight; and Grade 3, the reconstructed ACL did not run straight. The angle of the reconstructed ACL against the tibial plateau was also measured. RESULTS: All normal knees were classified as Grade 1. The 30 reconstructed knees were classified as follows: Grade 1, 12 cases; Grade 2, 7 cases; and Grade 3, 11 cases. The mean angle of the Grade 3 reconstructed ACL knees was significantly more vertical against the tibia as compared with the Grade 1 knees (P<.05). The postoperative KT-2000 side-to-side difference of the Grade 3 knees (2.8+/-4.5 mm) was larger than that of the Grade 1 knees (0.2+/-1.7 mm) and Grade 2 knees (-0.6+/-2.2 mm), but no statistically significant difference could be detected between the three groups in the postoperative KT-2000 data. CONCLUSION: This method is useful to evaluate ACL impingement against PCL, which cannot be detected by conventional arthroscopy during the operation. The surgeon should pay careful attention to the coronal angle of the reconstructed ACL.

Regional differences in the healing potential of the meniscus-an organ culture model to eliminate the influence of microvasculature and the synovium.

Meniscal healing is well known to be region-specific, and this is thought to be mainly due to its specific vascularity. The purpose of this study was to assess regional differences in the intrinsic healing potential of the meniscus, using an organ culture model to eliminate the influence of microvasculature and the synovium. A full-thickness circular defect, 1.5 mm in diameter, was created in the inner avascular zone in meniscal explants from rabbits. As a control, a column of 1.5 mm in diameter was removed then replanted in the area where it had been obtained (Group C). In the experimental group, a 1.5 mm-diameter meniscal graft obtained from the peripheral zone of the same specimen was implanted in the damaged area (Group T). These meniscal explants were cultured for 2, 4 or 6 weeks, and the relationship between the recipient tissue and the graft was examined using both gross and histological semiquantitative scoring. The 6-week gross-examination showed that the openings were more apparent in Group C, and the score of Group T was significantly higher than that of Group C (P=0.0152). Histologically, the healing responses after both 4 and 6 weeks of incubation were significantly better in Group T than in Group C (P=0.0237, 0.0281). These results using organ culture demonstrate that intrinsic healing potential differs even without the influence of vascular supply and the synovium, indicating that the superior healing potential in the peripheral zone may contribute to the good meniscal healing in this location.

An early return to vigorous activity may destabilize anterior cruciate ligaments reconstructed with hamstring grafts.

OBJECTIVE: To evaluate the actual date of the return to activity and its impact on the postsurgical stability of anterior cruciate ligament reconstruction (ACLR) using hamstring grafts. DESIGN: A retrospective analysis. The time of return to activity was determined by a questionnaire at 24 to 36 months after ACLRs. SETTING: An orthopedic center. PARTICIPANTS: Fifty consecutive patients who had ACLRs using hamstring grafts 24 to 36 months earlier. INTERVENTIONS: Not applicable. Main outcome measure The time of return to activity from a questionnaire and serial KT-2000 data at 3, 6, 12, 18, and 24 months postsurgery. RESULTS: Patients were divided into 2 groups according to their KT-2000 side-to-side difference at 12, 18, and 24 months postsurgery. Group I consisted of patients whose differences were 3mm or less. Group II consisted of patients whose differences were more than 3mm. At 12 and 18 months postsurgery, significant differences were detected for the time of return to running and full-speed running. A multiple regression analysis for postsurgical stability at 24 months and the time of return to these 5 activities indicated that the time of return to full-speed running and sports activities had an effect on ACL stability. CONCLUSIONS: An early return to vigorous activities is not recommended in patients undergoing ACLRs with hamstring grafts.

Spontaneous healing of acute anterior cruciate ligament (ACL) injuries - conservative treatment using an extension block soft brace without anterior stabilization.

To evaluate the spontaneous healing capability of acute anterior cruciate ligament (ACL) injuries, conservative treatment was applied in a selected group of 31 patients, who had low athletic demands. Each patient demonstrated a continuous ACL on magnetic resonance imaging (MRI), from the original femoral attachment through the tibial attachment, and an area of high intensity was detected in the substance of the ACL. The injured knees were treated using an extension block soft brace without anterior stabilization for 2-3 months. KT-2000 and MRI examinations were carried out regularly during the follow-up. Twenty-three knees (74%) were revealed to be stable in the follow-up examination, with an average of 16.1 months elapsing since the initial injuries. The KT-2000 side-to-side differences of 20 knees were less than 3 mm, and those of the other 3 knees were more than 3 mm but less than 5 mm. MRI confirmed that 21 injured ACL out of 23 knees maintained a femoral to tibial attachment and showed gradual reductions in image intensity. The positions of the other 2 injured ACL femoral attachments were different from the original femoral attachment: one was attached to the posterior cruciate ligament, and the other was located at the lateral femoral condyle anterior to the original femoral attachment. Eight knees (26%) subsequently required ACL reconstructions due to instability. This study indicates that an acutely injured ACL has healing capability. It also suggests that conservative management of the acute ACL injury can yield satisfactory results in a group of individuals who have low athletic demands and continuous ACL on MRI, provided the patients are willing to accept the slight risk of late ACL reconstruction and meniscal injury.