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Biol Psychol ; 70(1): 30-7, 2005 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-15979778

RESUMO

Social support is supposed to have a positive health effect via alteration of immunity. In this study, associations between perceived social support and immune systems were examined. Immunological assessments, e.g. T cell count, Natural Killer cell count, Interferon-gamma, Interleukin-4, and psychological assessments, e.g. Generic Job Stress Questionnaire were conducted on male employees. Two-way (social support x job stressor) analyses of covariance controlling for age, smoking, alcohol consumption, and exercise revealed that there were main effects of perceived social support on NK cell counts, IL-4, and Th1/Th2 balance. On the other hand, interaction effects were observed on T cell counts and INF-gamma production in vitro. Social support affects immune function in a way that is consistent with both the direct and buffering hypotheses depending on the sources of support and the immune parameter.


Assuntos
Células Matadoras Naturais/metabolismo , Percepção , Apoio Social , Estresse Psicológico/sangue , Linfócitos T Auxiliares-Indutores/metabolismo , Local de Trabalho/psicologia , Adulto , Antígenos CD4/sangue , Citometria de Fluxo , Humanos , Interferon gama/sangue , Interleucina-4/sangue , Contagem de Leucócitos , Masculino , Atividade Motora/fisiologia , Fumar , Inquéritos e Questionários
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