Dengue emergence in the temperate Argentinian province of Santa Fe, 2009-2020.

Dengue virus (DENV) transmission occurs primarily in tropical and subtropical climates, but within the last decade it has extended to temperate regions. Santa Fe, a temperate province in Argentina, has experienced an increase in dengue cases and virus circulation since 2009, with the recent 2020 outbreak being the largest in the province to date. The aim of this work is to describe spatio-temporal fluctuations of dengue cases from 2009 to 2020 in Santa Fe Province. The data presented in this work provide a detailed description of DENV transmission for Santa Fe Province by department. These data are useful to assist in investigating drivers of dengue emergence in Santa Fe Province and for developing a better understanding of the drivers and the impacts of ongoing dengue emergence in temperate regions across the world. This work provides data useful for future studies including those investigating socio-ecological, climatic, and environmental factors associated with DENV transmission, as well as those investigating other variables related to the biology and the ecology of vector-borne diseases.

Spatio-temporal analysis of leptospirosis incidence and its relationship with hydroclimatic indicators in northeastern Argentina.

Leptospirosis is considered the most globally widespread zoonotic illness; it has been classified as an emerging or reemerging infectious disease by the World Health Organization. Leptospirosis is a disease caused by a pathogenic spirochete of the genus Leptospira. The infection occurs by contacting with the urine of animal reservoirs or contaminated environments. Leptospirosis can be controlled by vaccines used mainly in animals, antibiotics given to exposed humans, and flood-affected people moved to a safe place. Northeastern Argentina accounts for the highest annual number of cases and deaths due to leptospirosis of the country. This interdisciplinary study aims to analyze the spatial and temporal distribution of leptospirosis, and assesses the hydroclimatic factors that give rise to the outbreaks in northeastern Argentina. The main goal is to detect the hydroclimatic indicators that can influence leptospirosis outbreaks occurrence in the northeastern Argentina. We perform a spatio-temporal analysis of the leptospirosis in the provinces of Santa Fe and Entre Ríos to distinguish the regions, years and seasons with the highest incidence of this disease. This study analyzes confirmed cases of leptospirosis between 2009 and 2018 years. Hydroclimatic indicators (monthly total precipitation, monthly river hydrometric level and Oceanic Niño Index) associated with outbreaks of leptospirosis vary in different spatial scales (provincial, departmental and cities). In the last outbreak of leptospirosis in 2015-2016 the number of cases was lower than expected. This could have been a consequence of increased prophylaxis in that flood event. Therefore, this is a variable that should be incorporated in future studies.